1h6f

Human TBX3, a transcription factor responsible for ulnar-mammary syndrome, bound to a palindromic DNA site

Method: X-RAY DIFFRACTION Dmax: 90.2 Å Quality: GOOD

SAXS 散射曲线 SAXS Profile

SAXS profile for 1h6f

P(r) 距离分布 P(r) Distribution

P(r) distribution for 1h6f
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1. 结构基本信息 1. Structure Basics

条目编号 entry_id1h6f
沉积日期 deposition_date2001-06-13
结构标题 titleHuman TBX3, a transcription factor responsible for ulnar-mammary syndrome, bound to a palindromic DNA site
关键词 keywords;TRANSCRIPTION FACTOR, TBX3, T-BOX TRANSCRIPTION FACTOR, ULNAR-MAMMARY SYNDROME, HOLT-ORAM-SYNDROME, IG-FOLD, DNA-BINDING, REPRESSOR, NUCLEAR PROTEIN, DEVELOPMENTAL PROTEIN ;; TRANSCRIPTION FACTOR
实验方法 methodX-RAY DIFFRACTION

2. SAXS 参数 (CRYSOL 理论计算) 2. SAXS Parameters (CRYSOL)

回转半径 Rg (Guinier) rg_guinier27.30
回转半径 Rg (电子) rg_electron26.24
零角强度 I(0) i072299600.00
分子量 molecular_weight58282.0 kDa
排除体积 excluded_volume69288 ų
包络体积 envelope_volume90697 ų
水化壳体积 shell_volume28857 ų
包络直径 envelope_diameter93.5
壳层 Rg shell_rg33.45
包络 Rg envelope_rg25.96
形状 Rg shape_rg26.18
总 Rg total_rg27.06
总原子数 total_atoms4044
残基数 n_residues418
球谐函数阶数 n_harmonics20
q 范围 q_range— – 0.5000 −1
数据点数 n_points101
壳层类型 shell_typedirectional
溶剂电子密度 solvent_density0.3340 e/ų
壳层衬度 contrast_shell0.0300 e/ų
CRYSOL 版本 crysol_version4.1.3

3. P(r) 距离分布 (GNOM 反演) 3. P(r) Analysis (GNOM)

最大尺寸 Dmax dmax90.2
Rg (实空间) rg_real27.24
Rg 误差 (实空间) rg_real_error0.70
I(0) (实空间) i0_real7.2300e+07
I(0) 误差 (实空间) i0_real_error1.0730e+06
Rg (倒空间) rg_reciprocal27.27
I(0) (倒空间) i0_reciprocal72300000.0000
解质量估计 total_estimate0.8965
解质量评级 solution_quality GOOD a GOOD solution
P(r) 峰数 n_peaks2
主峰位置 r_peak_primary31.1
偏度 Skewness skewness0.238
峰度 Kurtosis kurtosis-0.447
角度范围 angular_range— – 0.2900 −1
当前正则化参数 α current_alpha0.0000
最高正则化参数 α highest_alpha7014000.0000
实空间数据点数 n_real_points59
GNOM 版本 gnom_version4.1.3
质量判据 quality_criteria AN1: 0.000; Oscil: 0.897; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.995; Smooth: 0.964

4. 晶体学与实验 4. Crystallography & Experiment

5. 实体与聚合体信息 (4)

6. 折叠分类 (SCOP + CATH) 4 domains

SCOP 2.08 (2 domains)

结构域编号 domain_idd1h6fa_
类 Class classb — All beta proteins
折叠类型 Fold foldb.2 — Common fold of diphtheria toxin/transcription factors/cytochrome f
超家族 Superfamily superfamilyb.2.5 — p53-like transcription factors
家族 Family familyb.2.5.4 — T-box
结构域编号 domain_idd1h6fb_
类 Class classb — All beta proteins
折叠类型 Fold foldb.2 — Common fold of diphtheria toxin/transcription factors/cytochrome f
超家族 Superfamily superfamilyb.2.5 — p53-like transcription factors
家族 Family familyb.2.5.4 — T-box

CATH v4.4 (2 domains)

结构域编号 domain_id1h6fA00
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology40 — Immunoglobulin-like
同源超家族 H-superfamily homologous superfamily820 — Transcription factor, T-box
结构域编号 domain_id1h6fB00
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology40 — Immunoglobulin-like
同源超家族 H-superfamily homologous superfamily820 — Transcription factor, T-box

7. 引用文献 (2)

8. 文件与曲线 (10)