1hiw

TRIMERIC HIV-1 MATRIX PROTEIN

Method: X-RAY DIFFRACTION

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1. Protein Identity and Related Structures Protein Identity & Related Structures

HIV-1 MATRIX PROTEIN

Human immunodeficiency virus 1

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein homooligomer	Homooligomer	Protein 3	SULFATE ION × 3 water × 3	Consistent with protein count
2	Protein homooligomer	Homooligomer	Protein 3	SULFATE ION × 5 water × 3	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	GAG_HV1N5
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain A； PDBConstruct 3–133； UniProt 1–131 Author chain B； PDBConstruct 3–133； UniProt 1–131 Author chain C； PDBConstruct 3–133； UniProt 1–131 Author chain Q； PDBConstruct 3–133； UniProt 1–131 Author chain R； PDBConstruct 3–133； UniProt 1–131 Author chain S； PDBConstruct 3–133； UniProt 1–131

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	1hiw
Deposition date deposition_date	1996-02-28
Structure title title	TRIMERIC HIV-1 MATRIX PROTEIN
Keywords keywords	HIV-1, P17, HIV-1 MA, MATRIX PROTEIN; MATRIX PROTEIN
Experimental Method method	X-RAY DIFFRACTION

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

1hiw__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

1hiw__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

1hiw__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	24.96 Å
Rg (electron density)	23.85 Å
Total Rg	24.84 Å
Atom count	2698
Residues	338
Excluded volume	48008 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`1hiw__assembly_1__model_1`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download
2	1	`1hiw__assembly_2__model_1`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

Entity 1 Entity 1 polymer

Description description	HIV-1 MATRIX PROTEIN
Molecular weight formula_weight	15004.0 kDa
Source method src_method	man
Copy count entity_count	6

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	A,B,C,Q,R,S
Atom count atom_count	5488

HMGARASVLSGGELDKWEKIRLRPGGKKQYKLKHIVWASRELERFAVNPGLLETSEGCRQILGQLQPSLQTGSEELRSLYNTIAVLYCVHQRIDVKDTKEALDKIEEEQNKSKKKAQQAAADTGNNSQVSQNY

Source Source

Source organism organism	Human immunodeficiency virus 1
NCBI taxonomy ID ncbi_taxonomy_id	11676
Host organism host_organism	Escherichia coli

Entity 2 Entity 2 non-polymer

Description description	SULFATE ION
Molecular weight formula_weight	96.1 kDa
Source method src_method	syn
Copy count entity_count	8

Entity 3 Entity 3 water

Description description	water
Molecular weight formula_weight	18.0 kDa
Source method src_method	nat
Copy count entity_count	70

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6. Fold Classification (SCOP + CATH) 12 domains

SCOP 2.08 (6 domains)

Domain ID domain_id	d1hiwa_
Class class	a — All alpha proteins
Fold Fold fold	a.61 — Retroviral matrix proteins
Superfamily Superfamily superfamily	a.61.1 — Retroviral matrix proteins
Family Family family	a.61.1.1 — Immunodeficiency virus matrix proteins

Domain ID domain_id	d1hiwb_
Class class	a — All alpha proteins
Fold Fold fold	a.61 — Retroviral matrix proteins
Superfamily Superfamily superfamily	a.61.1 — Retroviral matrix proteins
Family Family family	a.61.1.1 — Immunodeficiency virus matrix proteins

Domain ID domain_id	d1hiwc_
Class class	a — All alpha proteins
Fold Fold fold	a.61 — Retroviral matrix proteins
Superfamily Superfamily superfamily	a.61.1 — Retroviral matrix proteins
Family Family family	a.61.1.1 — Immunodeficiency virus matrix proteins

Domain ID domain_id	d1hiwq_
Class class	a — All alpha proteins
Fold Fold fold	a.61 — Retroviral matrix proteins
Superfamily Superfamily superfamily	a.61.1 — Retroviral matrix proteins
Family Family family	a.61.1.1 — Immunodeficiency virus matrix proteins

Domain ID domain_id	d1hiwr_
Class class	a — All alpha proteins
Fold Fold fold	a.61 — Retroviral matrix proteins
Superfamily Superfamily superfamily	a.61.1 — Retroviral matrix proteins
Family Family family	a.61.1.1 — Immunodeficiency virus matrix proteins

Domain ID domain_id	d1hiws_
Class class	a — All alpha proteins
Fold Fold fold	a.61 — Retroviral matrix proteins
Superfamily Superfamily superfamily	a.61.1 — Retroviral matrix proteins
Family Family family	a.61.1.1 — Immunodeficiency virus matrix proteins

CATH v4.4 (6 domains)

Domain ID domain_id	1hiwA00
Class class	1 — Mainly Alpha
Architecture architecture	10 — Orthogonal Bundle
Topology topology	150 — DNA polymerase; domain 1
Homologous superfamily homologous superfamily	90 — Immunodeficiency lentiviruses, gag gene matrix protein p17

Domain ID domain_id	1hiwB00
Class class	1 — Mainly Alpha
Architecture architecture	10 — Orthogonal Bundle
Topology topology	150 — DNA polymerase; domain 1
Homologous superfamily homologous superfamily	90 — Immunodeficiency lentiviruses, gag gene matrix protein p17

Domain ID domain_id	1hiwC00
Class class	1 — Mainly Alpha
Architecture architecture	10 — Orthogonal Bundle
Topology topology	150 — DNA polymerase; domain 1
Homologous superfamily homologous superfamily	90 — Immunodeficiency lentiviruses, gag gene matrix protein p17

Domain ID domain_id	1hiwQ00
Class class	1 — Mainly Alpha
Architecture architecture	10 — Orthogonal Bundle
Topology topology	150 — DNA polymerase; domain 1
Homologous superfamily homologous superfamily	90 — Immunodeficiency lentiviruses, gag gene matrix protein p17

Domain ID domain_id	1hiwR00
Class class	1 — Mainly Alpha
Architecture architecture	10 — Orthogonal Bundle
Topology topology	150 — DNA polymerase; domain 1
Homologous superfamily homologous superfamily	90 — Immunodeficiency lentiviruses, gag gene matrix protein p17

Domain ID domain_id	1hiwS00
Class class	1 — Mainly Alpha
Architecture architecture	10 — Orthogonal Bundle
Topology topology	150 — DNA polymerase; domain 1
Homologous superfamily homologous superfamily	90 — Immunodeficiency lentiviruses, gag gene matrix protein p17

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Unit-cell length a length_a	64.423 Å
Unit-cell length b length_b	91.163 Å
Unit-cell length c length_c	73.997 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	102.91 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	12

Space group space_group	P 1 21 1
Space-group number int_tables_number	4
Crystal system crystal_system	—

Resolution resolution	2.300 Å
Low-resolution limit resolution_low	8.000 Å
R factor r_factor	0.2590
R_work r_work	0.2590
R_free r_free	0.3320

TRIMERIC HIV-1 MATRIX PROTEIN

1. Protein Identity and Related Structures Protein Identity & Related Structures

HIV-1 MATRIX PROTEIN

State in the Current Structure

Other States of the Same Protein in the Database

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

1hiw__assembly_1__model_1

1hiw__assembly_1__model_1 | I(q)

1hiw__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

5. Entities and Polymers Entities & Polymers (3)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 non-polymer

Entity 3 Entity 3 water

6. Fold Classification (SCOP + CATH) 12 domains

SCOP 2.08 (6 domains)

CATH v4.4 (6 domains)

7. Citations (1)

TRIMERIC HIV-1 MATRIX PROTEIN

1. Protein Identity and Related Structures Protein Identity & Related Structures

HIV-1 MATRIX PROTEIN

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

1hiw__assembly_1__model_1

1hiw__assembly_1__model_1 | I(q)

1hiw__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

5. Entities and Polymers Entities & Polymers (3)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 non-polymer

Entity 3 Entity 3 water

6. Fold Classification (SCOP + CATH) 12 domains

SCOP 2.08 (6 domains)

CATH v4.4 (6 domains)

7. Citations (1)