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1hon

STRUCTURE OF GUANINE NUCLEOTIDE (GPPCP) COMPLEX OF ADENYLOSUCCINATE SYNTHETASE FROM ESCHERICHIA COLI AT PH 6.5 AND 25 DEGREE CELSIUS

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

ADENYLOSUCCINATE SYNTHETASE

Escherichia coli

UniProt P0A7D4

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 2 AMINOPHOSPHONIC ACID-GUANYLATE ESTER × 1 water × 2 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1ch8 1cib

2 assemblies

Homodimer
1ade 1adi 1cg0 1cg1 1cg3 1cg4 1ch8 1cib 1gim 1gin 1hon 1hoo

22 assemblies; showing the first 12

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex

None

View Construct and Data Evidence
UniProt name PURA_ECOLI
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–431； UniProt 1–431 Author chain B； PDBConstruct 1–431； UniProt 1–431

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id1hon
Deposition date deposition_date1996-04-26
Structure title titleSTRUCTURE OF GUANINE NUCLEOTIDE (GPPCP) COMPLEX OF ADENYLOSUCCINATE SYNTHETASE FROM ESCHERICHIA COLI AT PH 6.5 AND 25 DEGREE CELSIUS
Keywords keywordsPURINE NUCLEOTIDE BIOSYNTHESIS, LIGASE, GTP-BINDING ENZYMES, SYNTHETASE, LIGASE (SYNTHETASE); LIGASE (SYNTHETASE)
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

1hon__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

1hon__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

1hon__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）28.51 Å
Rg (electron density)27.56 Å
Total Rg28.40 Å
Atom count8180
Residues862
Excluded volume118580 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 1hon__assembly_1__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

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6. Fold Classification (SCOP + CATH) 8 domains

SCOP 2.08 (2 domains)

Domain ID domain_idd1hona_
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.37 — P-loop containing nucleoside triphosphate hydrolases
Superfamily Superfamily superfamilyc.37.1 — P-loop containing nucleoside triphosphate hydrolases
Family Family familyc.37.1.10 — Nitrogenase iron protein-like
Domain ID domain_idd1honb_
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.37 — P-loop containing nucleoside triphosphate hydrolases
Superfamily Superfamily superfamilyc.37.1 — P-loop containing nucleoside triphosphate hydrolases
Family Family familyc.37.1.10 — Nitrogenase iron protein-like

CATH v4.4 (6 domains)

Domain ID domain_id1honA01
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology440 — Adenylosuccinate Synthetase; Chain A, domain 1
Homologous superfamily homologous superfamily10 — Adenylosuccinate Synthetase, subunit A, domain 1
Domain ID domain_id1honA02
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology300 — Adenylosuccinate Synthetase, subunit A; domain 2
Homologous superfamily homologous superfamily10 — Adenylosuccinate Synthetase, subunit A, domain 2
Domain ID domain_id1honA03
Class class3 — Alpha Beta
Architecture architecture90 — Alpha-Beta Complex
Topology topology170 — Adenylosuccinate Synthetase; Chain A, domain 3
Homologous superfamily homologous superfamily10 — Adenylosuccinate Synthetase, subunit A, domain 3
Domain ID domain_id1honB01
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology440 — Adenylosuccinate Synthetase; Chain A, domain 1
Homologous superfamily homologous superfamily10 — Adenylosuccinate Synthetase, subunit A, domain 1
Domain ID domain_id1honB02
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology300 — Adenylosuccinate Synthetase, subunit A; domain 2
Homologous superfamily homologous superfamily10 — Adenylosuccinate Synthetase, subunit A, domain 2
Domain ID domain_id1honB03
Class class3 — Alpha Beta
Architecture architecture90 — Alpha-Beta Complex
Topology topology170 — Adenylosuccinate Synthetase; Chain A, domain 3
Homologous superfamily homologous superfamily10 — Adenylosuccinate Synthetase, subunit A, domain 3
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7. Citations (3)