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1jb6

Crystal Structure of Dimerization Domain (1-33) of HNF-1alpha

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

HEPATOCYTE NUCLEAR FACTOR 1-ALPHA

OrganismNot specified

UniProt P22361

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 2 water × 2 Consistent with protein count
2 Protein homooligomer Homooligomer Protein 2 water × 2 Consistent with protein count
3 Protein homooligomer Homooligomer Protein 4 water × 4 Consistent with protein count
4 Protein homooligomer Homooligomer Protein 8 water × 8 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer
1g2y 1g2y 1g39 1g39 1jb6 1jb6 1lfb

7 assemblies

Homotetramer
1g2y 1g2y 1g2z 1g39 1g39 1jb6

6 assemblies

Other homooligomers
1jb6

1 assemblies

Heteromeric or nucleic-acid complex
1f93 1f93

2 assemblies

View Construct and Data Evidence
UniProt name HNF1A_MOUSE
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–33； UniProt 1–33 Author chain B； PDBConstruct 1–33； UniProt 1–33

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id1jb6
Deposition date deposition_date2001-06-01
Structure title titleCrystal Structure of Dimerization Domain (1-33) of HNF-1alpha
Keywords keywordsFour-helix bundle, non-canonical turn, TRANSCRIPTION; TRANSCRIPTION
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

1jb6__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

1jb6__assembly_1__model_1 | I(q)

10-2 10-1 105 106 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

1jb6__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）12.94 Å
Rg (electron density)12.02 Å
Total Rg13.33 Å
Atom count500
Residues62
Excluded volume9192 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 1jb6__assembly_1__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 1jb6__assembly_2__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
3 1 1jb6__assembly_3__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
4 1 1jb6__assembly_4__model_1 octameric （8） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (2)

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6. Fold Classification (SCOP + CATH) 2 domains

SCOP 2.08 (2 domains)

Domain ID domain_idd1jb6a_
Class classa — All alpha proteins
Fold Fold folda.34 — Dimerisation interlock
Superfamily Superfamily superfamilya.34.2 — Dimerization cofactor of HNF-1 alpha
Family Family familya.34.2.1 — Dimerization cofactor of HNF-1 alpha
Domain ID domain_idd1jb6b_
Class classa — All alpha proteins
Fold Fold folda.34 — Dimerisation interlock
Superfamily Superfamily superfamilya.34.2 — Dimerization cofactor of HNF-1 alpha
Family Family familya.34.2.1 — Dimerization cofactor of HNF-1 alpha
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7. Citations (6)