1jv2
CRYSTAL STRUCTURE OF THE EXTRACELLULAR SEGMENT OF INTEGRIN ALPHAVBETA3
1. Protein Identity and Related Structures Protein Identity & Related Structures
No usable UniProt protein identity is available for this entry.
The relationship tables retain this entry's assembly and composition data, but cross-PDB links for the same protein cannot be established reliably without a unified protein identity.
Assembly Composition of the Current Entry
| Assembly | Physical composition | Protein state | 蛋白 / DNA / RNA / 其他Polymer | Data consistency |
|---|---|---|---|---|
| 1 | Other combination | Heteromer | 2 / 0 / 0 / 7 | Consistent with protein count |
The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.
2. Structure Basics 2. Structure Basics
| Entry ID entry_id | 1jv2 |
| Deposition date deposition_date | 2001-08-28 |
| Structure title title | CRYSTAL STRUCTURE OF THE EXTRACELLULAR SEGMENT OF INTEGRIN ALPHAVBETA3 |
| Keywords keywords | ;genu, hybrid domain, beta-tail domain, PSI domain, EGF domain, MIDAS, ADMIDAS, Cage motif, propeller, A-domain, thigh domain, calf domain, CELL ADHESION ;; CELL ADHESION |
| Experimental Method method | X-RAY DIFFRACTION |
3. Official assembly/model SAXS Official SAXS Profiles
This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.
1jv2__assembly_1__model_1
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
1jv2__assembly_1__model_1 | I(q)
1jv2__assembly_1__model_1 | P(r) · Pending
| Rg（Guinier） | 40.11 Å |
| Rg (electron density) | 39.64 Å |
| Total Rg | 40.01 Å |
| Atom count | 11656 |
| Residues | 1466 |
| Excluded volume | 206810 ų |
| Maximum q | 0.500 Å⁻¹ |
4. Crystallography and Experiment 4. Crystallography & Experiment
5. Entities and Polymers Entities & Polymers (6)
6. Fold Classification (SCOP + CATH) 17 domains
SCOP 2.08 (9 domains)
| Domain ID domain_id | d1jv2a1 |
| Class class | b — All beta proteins |
| Fold Fold fold | b.1 — Immunoglobulin-like beta-sandwich |
| Superfamily Superfamily superfamily | b.1.15 — Integrin domains |
| Family Family family | b.1.15.1 — Integrin domains |
| Domain ID domain_id | d1jv2a2 |
| Class class | b — All beta proteins |
| Fold Fold fold | b.1 — Immunoglobulin-like beta-sandwich |
| Superfamily Superfamily superfamily | b.1.15 — Integrin domains |
| Family Family family | b.1.15.1 — Integrin domains |
| Domain ID domain_id | d1jv2a3 |
| Class class | b — All beta proteins |
| Fold Fold fold | b.1 — Immunoglobulin-like beta-sandwich |
| Superfamily Superfamily superfamily | b.1.15 — Integrin domains |
| Family Family family | b.1.15.1 — Integrin domains |
| Domain ID domain_id | d1jv2a4 |
| Class class | b — All beta proteins |
| Fold Fold fold | b.69 — 7-bladed beta-propeller |
| Superfamily Superfamily superfamily | b.69.8 — Integrin alpha N-terminal domain |
| Family Family family | b.69.8.1 — Integrin alpha N-terminal domain |
| Domain ID domain_id | d1jv2b1 |
| Class class | b — All beta proteins |
| Fold Fold fold | b.1 — Immunoglobulin-like beta-sandwich |
| Superfamily Superfamily superfamily | b.1.15 — Integrin domains |
| Family Family family | b.1.15.1 — Integrin domains |
| Domain ID domain_id | d1jv2b2 |
| Class class | c — Alpha and beta proteins (a/b) |
| Fold Fold fold | c.62 — vWA-like |
| Superfamily Superfamily superfamily | c.62.1 — vWA-like |
| Family Family family | c.62.1.1 — Integrin A (or I) domain |
| Domain ID domain_id | d1jv2b3 |
| Class class | d — Alpha and beta proteins (a+b) |
| Fold Fold fold | d.200 — Integrin beta tail domain |
| Superfamily Superfamily superfamily | d.200.1 — Integrin beta tail domain |
| Family Family family | d.200.1.1 — Integrin beta tail domain |
| Domain ID domain_id | d1jv2b4 |
| Class class | g — Small proteins |
| Fold Fold fold | g.3 — Knottins (small inhibitors, toxins, lectins) |
| Superfamily Superfamily superfamily | g.3.11 — EGF/Laminin |
| Family Family family | g.3.11.6 — Integrin beta EGF-like domains |
| Domain ID domain_id | d1jv2b5 |
| Class class | g — Small proteins |
| Fold Fold fold | g.3 — Knottins (small inhibitors, toxins, lectins) |
| Superfamily Superfamily superfamily | g.3.11 — EGF/Laminin |
| Family Family family | g.3.11.6 — Integrin beta EGF-like domains |
CATH v4.4 (8 domains)
| Domain ID domain_id | 1jv2A01 |
| Class class | 2 — Mainly Beta |
| Architecture architecture | 130 — 7 Propeller |
| Topology topology | 10 — Methylamine Dehydrogenase; Chain H |
| Homologous superfamily homologous superfamily | 130 — Integrin alpha, N-terminal |
| Domain ID domain_id | 1jv2A02 |
| Class class | 2 — Mainly Beta |
| Architecture architecture | 60 — Sandwich |
| Topology topology | 40 — Immunoglobulin-like |
| Homologous superfamily homologous superfamily | 1460 — Integrin domains. Chain A, domain 2 |
| Domain ID domain_id | 1jv2A03 |
| Class class | 2 — Mainly Beta |
| Architecture architecture | 60 — Sandwich |
| Topology topology | 40 — Immunoglobulin-like |
| Homologous superfamily homologous superfamily | 1510 — ntegrin, alpha v. Chain A, domain 3 |
| Domain ID domain_id | 1jv2A04 |
| Class class | 2 — Mainly Beta |
| Architecture architecture | 60 — Sandwich |
| Topology topology | 40 — Immunoglobulin-like |
| Homologous superfamily homologous superfamily | 1530 — ntegrin, alpha v. Chain A, domain 4 |
| Domain ID domain_id | 1jv2B01 |
| Class class | 2 — Mainly Beta |
| Architecture architecture | 60 — Sandwich |
| Topology topology | 40 — Immunoglobulin-like |
| Homologous superfamily homologous superfamily | 1510 — ntegrin, alpha v. Chain A, domain 3 |
| Domain ID domain_id | 1jv2B02 |
| Class class | 3 — Alpha Beta |
| Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| Topology topology | 50 — Rossmann fold |
| Homologous superfamily homologous superfamily | 410 — von Willebrand factor, type A domain |
| Domain ID domain_id | 1jv2B03 |
| Class class | 2 — Mainly Beta |
| Architecture architecture | 10 — Ribbon |
| Topology topology | 25 — Laminin |
| Homologous superfamily homologous superfamily | 10 — Laminin |
| Domain ID domain_id | 1jv2B04 |
| Class class | 4 — Few Secondary Structures |
| Architecture architecture | 10 — Irregular |
| Topology topology | 1240 — Hormone receptor fold |
| Homologous superfamily homologous superfamily | 30 — |