1k6w

The Structure of Escherichia coli Cytosine Deaminase

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Cytosine Deaminase

Escherichia coli

UniProt P25524

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 6 FE (III) ION × 6 water × 6 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name CODA_ECOLI
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 1–426; UniProt 1–426

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id1k6w
Deposition date deposition_date2001-10-17
Structure title titleThe Structure of Escherichia coli Cytosine Deaminase
Keywords keywordscytosine deaminase, alpha-beta barrel, hexamer, domain swap, HYDROLASE; HYDROLASE
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

1k6w__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

1k6w__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

1k6w__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)41.47 Å
Rg (electron density)40.99 Å
Total Rg41.39 Å
Atom count19956
Residues2538
Excluded volume353160 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 1k6w__assembly_1__model_1 hexameric (6) Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

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6. Fold Classification (SCOP + CATH) 4 domains

SCOP 2.08 (2 domains)

Domain ID domain_idd1k6wa1
Class classb — All beta proteins
Fold Fold foldb.92 — Composite domain of metallo-dependent hydrolases
Superfamily Superfamily superfamilyb.92.1 — Composite domain of metallo-dependent hydrolases
Family Family familyb.92.1.2 — Cytosine deaminase
Domain ID domain_idd1k6wa2
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.1 — TIM beta/alpha-barrel
Superfamily Superfamily superfamilyc.1.9 — Metallo-dependent hydrolases
Family Family familyc.1.9.5 — Cytosine deaminase catalytic domain

CATH v4.4 (2 domains)

Domain ID domain_id1k6wA01
Class class2 — Mainly Beta
Architecture architecture30 — Roll
Topology topology40 — Urease, subunit C; domain 1
Homologous superfamily homologous superfamily10 — Urease, subunit C, domain 1
Domain ID domain_id1k6wA02
Class class3 — Alpha Beta
Architecture architecture20 — Alpha-Beta Barrel
Topology topology20 — TIM Barrel
Homologous superfamily homologous superfamily140 — Metal-dependent hydrolases
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7. Citations (1)