Methionine synthase
Escherichia coli
当前结构中的状态
| Assembly | 物理组成 | 蛋白状态 | 分子拷贝数 | 共同组分 | 数据核对 |
|---|---|---|---|---|---|
| 1 | 蛋白单体 | 单体 | 蛋白 1 | SULFATE ION × 1 COBALAMIN × 1 | 与蛋白数一致 |
数据库中的同蛋白其他状态
查看构建体与数据证据
| UniProt名称 | METH_ECOLI |
| Isoform | — |
| PDB实体 | 1 |
| 链与序列区间 | 作者链 A； PDB构建体 1–577； UniProt 651–1227 |
1k98
AdoMet complex of MetH C-terminal fragment
1. 蛋白身份与相关结构 Protein Identity & Related Structures
页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。
2. 结构基本信息 2. Structure Basics
| 条目编号 entry_id | 1k98 |
| 沉积日期 deposition_date | 2001-10-27 |
| 结构标题 title | AdoMet complex of MetH C-terminal fragment |
| 关键词 keywords | AdoMet binding, MOTION OF 4-HELIX BUNDLE, DOMAIN INTERACTIONS, TRANSFERASE; TRANSFERASE |
| 实验方法 method | X-RAY DIFFRACTION |
3. Official assembly/model 理论 SAXS Official SAXS Profiles
页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。
1k98__assembly_1__model_1
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
1k98__assembly_1__model_1 | I(q)
1k98__assembly_1__model_1 | P(r) · Pending
| Rg（Guinier） | 27.42 Å |
| Rg（电子密度） | 26.43 Å |
| 总 Rg | 27.07 Å |
| 原子数 | 4662 |
| 残基数 | 577 |
| 排除体积 | 82666 ų |
| 最大 q | 0.500 Å⁻¹ |
4. 晶体学与实验 4. Crystallography & Experiment
5. 实体与聚合物信息 Entities & Polymers (3)
6. 折叠分类 (SCOP + CATH) 7 domains
SCOP 2.08 (3 domains)
| 结构域编号 domain_id | d1k98a1 |
| 类 Class class | a — All alpha proteins |
| 折叠类型 Fold fold | a.46 — Methionine synthase domain-like |
| 超家族 Superfamily superfamily | a.46.1 — Methionine synthase domain |
| 家族 Family family | a.46.1.1 — Methionine synthase domain |
| 结构域编号 domain_id | d1k98a2 |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.23 — Flavodoxin-like |
| 超家族 Superfamily superfamily | c.23.6 — Cobalamin (vitamin B12)-binding domain |
| 家族 Family family | c.23.6.1 — Cobalamin (vitamin B12)-binding domain |
| 结构域编号 domain_id | d1k98a3 |
| 类 Class class | d — Alpha and beta proteins (a+b) |
| 折叠类型 Fold fold | d.173 — Methionine synthase activation domain-like |
| 超家族 Superfamily superfamily | d.173.1 — Methionine synthase activation domain-like |
| 家族 Family family | d.173.1.1 — Methionine synthase SAM-binding domain |
CATH v4.4 (4 domains)
| 结构域编号 domain_id | 1k98A01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 280 — Cobalamin-binding domain |
| 结构域编号 domain_id | 1k98A02 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 10 — Roll |
| 拓扑 Topology topology | 196 — Cobalamin-dependent Methionine Synthase; domain 1 |
| 同源超家族 H-superfamily homologous superfamily | 10 — Vitamin B12-dependent methionine synthase, activation domain |
| 结构域编号 domain_id | 1k98A03 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 1240 — Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 |
| 同源超家族 H-superfamily homologous superfamily | 10 — Methionine synthase domain |
| 结构域编号 domain_id | 1k98A04 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 288 — Cobalamin-dependent Methionine Synthase; domain 2 |
| 同源超家族 H-superfamily homologous superfamily | 10 — Cobalamin-dependent Methionine Synthase, domain 2 |