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1lrr

CRYSTAL STRUCTURE OF E. COLI SEQA COMPLEXED WITH HEMIMETHYLATED DNA

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

SeqA protein

Escherichia coli

UniProt P36658

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Monomer Protein 1 DNA 2 5'-D(*CP*AP*CP*CP*GP*AP*TP*CP*GP*AP*CP*T)-3' × 1 5'-D(*AP*GP*TP*CP*GP*(6MA)P*TP*CP*GP*GP*TP*G)-3' × 1 water × 3 Consistent with all polymers
2 Protein–DNA Monomer Protein 1 DNA 2 5'-D(*CP*AP*CP*CP*GP*AP*TP*CP*GP*AP*CP*T)-3' × 1 5'-D(*AP*GP*TP*CP*GP*(6MA)P*TP*CP*GP*GP*TP*G)-3' × 1 water × 2 Consistent with all polymers

Other States of the Same Protein in the Database

Monomer

None

Homodimer
1xrx 1xrx

2 assemblies

Homotetramer

None

Other homooligomers
1xrx

1 assemblies

Heteromeric or nucleic-acid complex
1iu3 1j3e 1lrr 1lrr

4 assemblies

View Construct and Data Evidence
UniProt name SEQA_ECOLI
Isoform —
PDB entities 3
Chains and sequence ranges Author chain A； PDBConstruct 1–131； UniProt 51–181 Author chain D； PDBConstruct 1–131； UniProt 51–181

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id1lrr
Deposition date deposition_date2002-05-15
Structure title titleCRYSTAL STRUCTURE OF E. COLI SEQA COMPLEXED WITH HEMIMETHYLATED DNA
Keywords keywordsprotein-dna complex, replication, methylated GATC, REPLICATION INHIBITOR-DNA COMPLEX; REPLICATION INHIBITOR/DNA
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

1lrr__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

1lrr__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

1lrr__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）17.55 Å
Rg (electron density)16.55 Å
Total Rg17.41 Å
Atom count1429
Residues141
Excluded volume23960 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 1lrr__assembly_1__model_1 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 1lrr__assembly_2__model_1 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (4)

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6. Fold Classification (SCOP + CATH) 4 domains

SCOP 2.08 (2 domains)

Domain ID domain_idd1lrra_
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.228 — Replication modulator SeqA, C-terminal DNA-binding domain
Superfamily Superfamily superfamilyd.228.1 — Replication modulator SeqA, C-terminal DNA-binding domain
Family Family familyd.228.1.1 — Replication modulator SeqA, C-terminal DNA-binding domain
Domain ID domain_idd1lrrd_
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.228 — Replication modulator SeqA, C-terminal DNA-binding domain
Superfamily Superfamily superfamilyd.228.1 — Replication modulator SeqA, C-terminal DNA-binding domain
Family Family familyd.228.1.1 — Replication modulator SeqA, C-terminal DNA-binding domain

CATH v4.4 (2 domains)

Domain ID domain_id1lrrA00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology1380 — Replication modulator SeqA, C-terminal DNA-binding domain
Homologous superfamily homologous superfamily10 — Replication modulator SeqA, C-terminal DNA-binding domain
Domain ID domain_id1lrrD00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology1380 — Replication modulator SeqA, C-terminal DNA-binding domain
Homologous superfamily homologous superfamily10 — Replication modulator SeqA, C-terminal DNA-binding domain
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7. Citations (1)