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1neb

SH3 DOMAIN FROM HUMAN NEBULIN, NMR, MINIMIZED AVERAGE STRUCTURE

Method: SOLUTION NMR Dmax: 41.0 Å Quality: GOOD
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1. Protein Identity and Related Structures Protein Identity & Related Structures

NEBULIN

Homo sapiens

UniProt P20929

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Protein monomer Monomer Protein × 1 PDB declaration: monomeric（1） Consistent with protein copy count Chain A； UniProt 918–977 Fragment：SH3 DOMAIN No other associated polymer SOLUTION NMR NMR measurement conditions：pH 6.9；300 K Resolution not provided

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

Other PDB Difference from Current Entry 1NEB Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Method and Experimental Conditions Structure Quality
1ARK SH3 DOMAIN FROM HUMAN NEBULIN, NMR, 15 STRUCTURES Deposited 1997-08-07 Different construct Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric
Chain A 918–977（60 aa） Fragment：SH3 DOMAIN, RESIDUES 6610 - 6669
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 6.9；300 K
Resolution not provided

1 other PDB entries and 1 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name NEBU_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–60； UniProt 918–977

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

SAXS scattering curve SAXS Profile

SAXS profile for 1neb

P(r) Distance Distribution P(r) Distribution

P(r) distribution for 1neb
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2. Structure Basics 2. Structure Basics

Entry ID entry_id1neb
Deposition date deposition_date1997-08-07
Structure title titleSH3 DOMAIN FROM HUMAN NEBULIN, NMR, MINIMIZED AVERAGE STRUCTURE
Keywords keywordsSH3 DOMAIN, NEBULIN, Z-DISK ASSEMBLY, ACTIN-BINDING; SH3 DOMAIN
Experimental Method methodSOLUTION NMR
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3. SAXS Parameters (CRYSOL theoretical calculation) 3. SAXS Parameters (CRYSOL)

Radius of gyration Rg (Guinier) rg_guinier12.40 Å
Radius of gyration Rg (electron density) rg_electron10.84 Å
Forward intensity I(0) i01078840.00
Molecular weight molecular_weight6605.0 kDa
Excluded volume excluded_volume8179 ų
Envelope volume envelope_volume9648 ų
Hydration-shell volume shell_volume7864 ų
Envelope diameter envelope_diameter40.0 Å
Shell Rg shell_rg16.12 Å
Envelope Rg envelope_rg11.29 Å
Shape Rg shape_rg10.78 Å
Total Rg total_rg12.44 Å
Total atoms total_atoms905
Residues n_residues60
Spherical-harmonic order n_harmonics20
q range q_range— – 0.5000 Å−1
Data points n_points101
Shell type shell_typedirectional
Solvent electron density solvent_density0.3340 e/ų
Shell contrast contrast_shell0.0300 e/ų
CRYSOL version crysol_version4.1.3
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4. P(r) Distance Distribution (GNOM inversion) 4. P(r) Analysis (GNOM)

Maximum dimension Dmax dmax41.0 Å
Rg (real space) rg_real12.32 Å
Rg uncertainty (real space) rg_real_error0.24 Å
I(0) (real space) i0_real1.0790e+06
I(0) uncertainty (real space) i0_real_error1.0710e+04
Rg (reciprocal space) rg_reciprocal12.32 Å
I(0) (reciprocal space) i0_reciprocal1079000.0000
Solution quality estimate total_estimate0.8740
Solution quality rating solution_quality GOOD a GOOD solution
P(r) peaks n_peaks2
Primary peak position r_peak_primary16.1 Å
Skewness Skewness skewness0.164
Kurtosis Kurtosis kurtosis-0.229
Angular range angular_range— – 0.5000 Å−1
Current regularization parameter α current_alpha0.0000
Highest regularization parameter α highest_alpha268100.0000
Real-space data points n_real_points80
GNOM version gnom_version4.1.3
Quality Criteria quality_criteria AN1: 0.000; Oscil: 0.790; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.999; Smooth: 0.989
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5. Crystallography and Experiment 5. Crystallography & Experiment

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6. Entities and Polymers Entities & Polymers (1)

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7. Fold Classification (SCOP + CATH) 2 domains

SCOP 2.08 (1 domains)

Domain ID domain_idd1neba_
Class classb — All beta proteins
Fold Fold foldb.34 — SH3-like barrel
Superfamily Superfamily superfamilyb.34.2 — SH3-domain
Family Family familyb.34.2.1 — SH3-domain

CATH v4.4 (1 domains)

Domain ID domain_id1nebA00
Class class2 — Mainly Beta
Architecture architecture30 — Roll
Topology topology30 — SH3 type barrels.
Homologous superfamily homologous superfamily40 — SH3 Domains
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8. Citations (1)

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9. Files and Curves (10)