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1nlw

Crystal structure of Mad-Max recognizing DNA

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

MAD PROTEIN

Homo sapiens

UniProt Q05195

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Heteromer Protein 2 DNA 2 5'-D(*GP*AP*GP*TP*AP*GP*CP*AP*CP*GP*TP*GP*CP*TP*AP*CP*TP*C)-3' × 2 MAX PROTEIN × 1 （P61244） water × 4 Consistent with all polymers
2 Protein–DNA Heteromer Protein 2 DNA 2 5'-D(*GP*AP*GP*TP*AP*GP*CP*AP*CP*GP*TP*GP*CP*TP*AP*CP*TP*C)-3' × 2 MAX PROTEIN × 1 （P61244） water × 4 Consistent with all polymers

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1e91 1nlw 1nlw 1pd7 1s5q

5 assemblies

View Construct and Data Evidence
UniProt name MAD_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain A； PDBConstruct 1–80； UniProt 57–136 Author chain D； PDBConstruct 1–80； UniProt 57–136

MAX PROTEIN

Homo sapiens

UniProt P61244

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Heteromer Protein 2 DNA 2 5'-D(*GP*AP*GP*TP*AP*GP*CP*AP*CP*GP*TP*GP*CP*TP*AP*CP*TP*C)-3' × 2 MAD PROTEIN × 1 （Q05195） water × 4 Consistent with all polymers
2 Protein–DNA Heteromer Protein 2 DNA 2 5'-D(*GP*AP*GP*TP*AP*GP*CP*AP*CP*GP*TP*GP*CP*TP*AP*CP*TP*C)-3' × 2 MAD PROTEIN × 1 （Q05195） water × 4 Consistent with all polymers

Other States of the Same Protein in the Database

Monomer

None

Homodimer
1r05

1 assemblies

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1an2 1hlo 1nkp 1nkp 1nlw 1nlw 5eyo 5eyo 6g6j 6g6j 6g6k 6g6k

18 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name MAX_HUMAN
Isoform —
PDB entities 3
Chains and sequence ranges Author chain B； PDBConstruct 1–76； UniProt 24–99 Author chain E； PDBConstruct 1–76； UniProt 24–99

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id1nlw
Deposition date deposition_date2003-01-07
Structure title titleCrystal structure of Mad-Max recognizing DNA
Keywords keywordstranscription factor, DNA, bHLHZ, TRANSCRIPTION-DNA COMPLEX; TRANSCRIPTION/DNA
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

1nlw__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

1nlw__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

1nlw__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）25.30 Å
Rg (electron density)25.61 Å
Total Rg25.86 Å
Atom count2003
Residues191
Excluded volume32917 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 1nlw__assembly_1__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 1nlw__assembly_2__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (4)

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6. Fold Classification (SCOP + CATH) 8 domains

SCOP 2.08 (4 domains)

Domain ID domain_idd1nlwa_
Class classa — All alpha proteins
Fold Fold folda.38 — HLH-like
Superfamily Superfamily superfamilya.38.1 — HLH, helix-loop-helix DNA-binding domain
Family Family familya.38.1.1 — HLH, helix-loop-helix DNA-binding domain
Domain ID domain_idd1nlwb_
Class classa — All alpha proteins
Fold Fold folda.38 — HLH-like
Superfamily Superfamily superfamilya.38.1 — HLH, helix-loop-helix DNA-binding domain
Family Family familya.38.1.1 — HLH, helix-loop-helix DNA-binding domain
Domain ID domain_idd1nlwd_
Class classa — All alpha proteins
Fold Fold folda.38 — HLH-like
Superfamily Superfamily superfamilya.38.1 — HLH, helix-loop-helix DNA-binding domain
Family Family familya.38.1.1 — HLH, helix-loop-helix DNA-binding domain
Domain ID domain_idd1nlwe_
Class classa — All alpha proteins
Fold Fold folda.38 — HLH-like
Superfamily Superfamily superfamilya.38.1 — HLH, helix-loop-helix DNA-binding domain
Family Family familya.38.1.1 — HLH, helix-loop-helix DNA-binding domain

CATH v4.4 (4 domains)

Domain ID domain_id1nlwA00
Class class4 — Few Secondary Structures
Architecture architecture10 — Irregular
Topology topology280 — MYOD Basic-Helix-Loop-Helix Domain, subunit B
Homologous superfamily homologous superfamily10 — Helix-loop-helix DNA-binding domain
Domain ID domain_id1nlwB00
Class class4 — Few Secondary Structures
Architecture architecture10 — Irregular
Topology topology280 — MYOD Basic-Helix-Loop-Helix Domain, subunit B
Homologous superfamily homologous superfamily10 — Helix-loop-helix DNA-binding domain
Domain ID domain_id1nlwD00
Class class4 — Few Secondary Structures
Architecture architecture10 — Irregular
Topology topology280 — MYOD Basic-Helix-Loop-Helix Domain, subunit B
Homologous superfamily homologous superfamily10 — Helix-loop-helix DNA-binding domain
Domain ID domain_id1nlwE00
Class class4 — Few Secondary Structures
Architecture architecture10 — Irregular
Topology topology280 — MYOD Basic-Helix-Loop-Helix Domain, subunit B
Homologous superfamily homologous superfamily10 — Helix-loop-helix DNA-binding domain
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7. Citations (1)