SAXSdb — 1npo

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1. Protein Identity and Related Structures Protein Identity & Related Structures

NEUROPHYSIN II

OrganismNot specified

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 4	OXYTOCIN × 2	Consistent with protein count
2	Protein heterocomplex	Heteromer	Protein 8	OXYTOCIN × 4	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	NEU2_BOVIN
Isoform	—
PDB entities	1, 3
Chains and sequence ranges	Author chain A； PDBConstruct 1–95； UniProt 32–126 Author chain C； PDBConstruct 1–95； UniProt 32–126

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	1npo
Deposition date deposition_date	1996-02-01
Structure title title	BOVINE NEUROPHYSIN II COMPLEX WITH OXYTOCIN
Keywords keywords	COMPLEX (HORMONE TRANSPORT-HORMONE), HYPOTHALAMUS, COMPLEX (HORMONE TRANSPORT-HORMONE) complex; COMPLEX (HORMONE TRANSPORT/HORMONE)
Experimental Method method	X-RAY DIFFRACTION

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

1npo__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

1npo__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

1npo__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	16.36 Å
Rg (electron density)	16.02 Å
Total Rg	16.75 Å
Atom count	1247
Residues	178
Excluded volume	21717 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`1npo__assembly_1__model_1`	tetrameric （4）	Success	4.1.3-1-20251215 (887e7ef)	View Download
2	1	`1npo__assembly_2__model_1`	octameric （8）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

Entity 1 Entity 1 polymer

Description description	NEUROPHYSIN II
Molecular weight formula_weight	9890.3 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	A
Atom count atom_count	1247

AMSDLELRQCLPCGPGGKGRCFGPSICCGDELGCFVGTAEALRCQEENYLPSPCQSGQKPCGSGGRCAAAGICCNDESCVTEPECREGVGFPRRV

Entity 2 Entity 2 polymer

Description description	OXYTOCIN
Molecular weight formula_weight	1010.2 kDa
Source method src_method	man
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	B,D

CYIQNCPLG

Entity 3 Entity 3 polymer

Description description	NEUROPHYSIN II
Molecular weight formula_weight	9832.1 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	C

AMSDLELRQCLPCGPGGAGRCFGPSICCGDELGCFVGTAEALRCQEENYLPSPCQSGQKPCGSGGRCAAAGICCNDESCVTEPECREGVGFPRRV

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6. Fold Classification (SCOP + CATH) 4 domains

SCOP 2.08 (2 domains)

Domain ID domain_id	d1npoa_
Class class	b — All beta proteins
Fold Fold fold	b.9 — Neurophysin II
Superfamily Superfamily superfamily	b.9.1 — Neurophysin II
Family Family family	b.9.1.1 — Neurophysin II

Domain ID domain_id	d1npoc_
Class class	b — All beta proteins
Fold Fold fold	b.9 — Neurophysin II
Superfamily Superfamily superfamily	b.9.1 — Neurophysin II
Family Family family	b.9.1.1 — Neurophysin II

CATH v4.4 (2 domains)

Domain ID domain_id	1npoA00
Class class	2 — Mainly Beta
Architecture architecture	60 — Sandwich
Topology topology	9 — Neurophysin II; Chain A
Homologous superfamily homologous superfamily	10 — Neurohypophysial hormone domain

Domain ID domain_id	1npoC00
Class class	2 — Mainly Beta
Architecture architecture	60 — Sandwich
Topology topology	9 — Neurophysin II; Chain A
Homologous superfamily homologous superfamily	10 — Neurohypophysial hormone domain

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Unit-cell length a length_a	69.050 Å
Unit-cell length b length_b	69.050 Å
Unit-cell length c length_c	113.260 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	16

Space group space_group	P 41 21 2
Space-group number int_tables_number	92
Crystal system crystal_system	—

Resolution resolution	3.000 Å
Low-resolution limit resolution_low	8.000 Å
R factor r_factor	0.1820
R_work r_work	0.1820
R_free r_free	0.2660

BOVINE NEUROPHYSIN II COMPLEX WITH OXYTOCIN

1. Protein Identity and Related Structures Protein Identity & Related Structures

NEUROPHYSIN II

State in the Current Structure

Other States of the Same Protein in the Database

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

1npo__assembly_1__model_1

1npo__assembly_1__model_1 | I(q)

1npo__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (3)

Entity 1 Entity 1 polymer

Polymer Polymer

Entity 2 Entity 2 polymer

Polymer Polymer

Entity 3 Entity 3 polymer

Polymer Polymer

6. Fold Classification (SCOP + CATH) 4 domains

SCOP 2.08 (2 domains)

CATH v4.4 (2 domains)

7. Citations (4)

BOVINE NEUROPHYSIN II COMPLEX WITH OXYTOCIN

1. Protein Identity and Related Structures Protein Identity & Related Structures

NEUROPHYSIN II

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

1npo__assembly_1__model_1

1npo__assembly_1__model_1 | I(q)

1npo__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (3)

Entity 1 Entity 1 polymer

Polymer Polymer

Entity 2 Entity 2 polymer

Polymer Polymer

Entity 3 Entity 3 polymer

Polymer Polymer

6. Fold Classification (SCOP + CATH) 4 domains

SCOP 2.08 (2 domains)

CATH v4.4 (2 domains)

7. Citations (4)