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1MK3
SOLUTION STRUCTURE OF HUMAN BCL-W PROTEIN
Deposited 2002-08-28
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Different construct
Different mutation/modification
Different experimental conditions
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Assembly 1
Protein monomer
Monomer；Protein × 1
PDB declaration: monomeric
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Chain A
2–171（170 aa）
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Mutation：P116V
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No recorded non-water small molecule
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SOLUTION NMR
NMR measurement conditions
pH 7.3；298 K；Ionic strength (raw mmCIF value) 10 mM NaCl；Pressure 1
NMR sample composition
1.4 mM Bcl-w protein U-15N,13C, 20 mM phosphate buffer | 90% H2O/10% D2O
NMR sample composition
1.3 mM Bcl-w protein U-15N, 20 mM phosphate buffer | 90% H2O/10% D2O
NMR sample composition
0.5 mM Bcl-w protein U-15N, 6 MG/ML PF1-PHAGE | 90% H2O/10% D2O
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Resolution not provided
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1ZY3
Structural model of complex of Bcl-w protein with Bid BH3-peptide
Deposited 2005-06-09
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Different construct
Different mutation/modification
Different oligomeric state
Different experimental conditions
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Assembly 1
Protein heterocomplex
Heteromer；Protein × 2
PDB declaration: dimeric
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Chain A
2–171（170 aa）
Fragment：residues 2-171
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Mutation：P116V
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No recorded non-water small molecule
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SOLUTION NMR
NMR measurement conditions
pH 7；303 K；Ionic strength (raw mmCIF value) 10 mM NaCl；Pressure 1
NMR sample composition
0.7 mM Bcl-w U-15N,13C, 0.7 mM Bid BH3-peptide, 20 mM phosphate buffer, 90% H2O, 10% D2O | 90% H2O/10% D2O
NMR sample composition
0.7 mM Bcl-w U-15N, 0.7 mM Bid BH3-peptide, 20 mM phosphate buffer, 90% H2O, 10% D2O | 90% H2O/10% D2O
NMR sample composition
0.7 mM Bid BH3-peptide U-15N, 0.7 mM Bcl-w, 20 mM phosphate buffer, 90% H2O, 10% D2O | 90% H2O/10% D2O
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Resolution not provided
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2Y6W
Structure of a Bcl-w dimer
Deposited 2011-01-27
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Different construct
Different mutation/modification
Different oligomeric state
Different ligand/ion
Different experimental method
Different experimental conditions
Different structure-quality metrics
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Assembly 1
Protein homooligomer
Homooligomer；Protein × 2
PDB declaration: dimeric
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Chain A
1–164（164 aa）
Fragment：C-TERMINAL TRUNCATION, RESIDUES 1-164
Chain B
1–164（164 aa）
Fragment：C-TERMINAL TRUNCATION, RESIDUES 1-164
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Mutation：YES
Mutation：YES
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PEG DI(HYDROXYETHYL)ETHER × 5
PGE TRIETHYLENE GLYCOL × 1
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X-RAY DIFFRACTION
X-ray crystallization conditions
pH 6.5；5% (W/V) PEG 3000, 40% (W/V) PEG 400, 0.1M MES PH 6.5.
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Resolution 2.00 Å
R-free 0.244
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4CIM
Complex of a Bcl-w BH3 mutant with a BH3 domain
Deposited 2013-12-12
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Different construct
Different mutation/modification
Different oligomeric state
Different ligand/ion
Different experimental method
Different experimental conditions
Different structure-quality metrics
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Assembly 1
Protein homooligomer
Homooligomer；Protein × 2
PDB declaration: dimeric
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Chain B
1–163（163 aa）
Chain Q
38–58（21 aa）
Fragment：RESIDUES 38-58
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Mutation：YES
Mutation：YES
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EDO 1,2-ETHANEDIOL × 7
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X-RAY DIFFRACTION
X-ray crystallization conditions
pH 8；1 M TRISODIUM CITRATE 0.1 M IMIDAZOLE, PH 8.0
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Resolution 1.50 Å
R-free 0.210
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4CIM
Complex of a Bcl-w BH3 mutant with a BH3 domain
Deposited 2013-12-12
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Different construct
Different mutation/modification
Different oligomeric state
Different ligand/ion
Different experimental method
Different experimental conditions
Different structure-quality metrics
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Assembly 2
Protein homooligomer
Homooligomer；Protein × 2
PDB declaration: dimeric
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Chain A
1–163（163 aa）
Chain P
38–58（21 aa）
Fragment：RESIDUES 38-58
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Mutation：YES
Mutation：YES
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EDO 1,2-ETHANEDIOL × 9
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X-RAY DIFFRACTION
X-ray crystallization conditions
pH 8；1 M TRISODIUM CITRATE 0.1 M IMIDAZOLE, PH 8.0
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Resolution 1.50 Å
R-free 0.210
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