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1o0s

Crystal Structure of Ascaris suum Malic Enzyme Complexed with NADH

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

NAD-dependent malic enzyme

OrganismNot specified

UniProt P27443

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 4 TARTRONATE × 4 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE × 4 water × 4 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer
1llq 1o0s

2 assemblies

Other homooligomers

None

Heteromeric or nucleic-acid complex

None

View Construct and Data Evidence
UniProt name MAOM_ASCSU
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–605； UniProt 39–643 Author chain B； PDBConstruct 1–605； UniProt 39–643

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id1o0s
Deposition date deposition_date2003-02-24
Structure title titleCrystal Structure of Ascaris suum Malic Enzyme Complexed with NADH
Keywords keywordsOxidoreductase, Oxidative decarboxylase, Rossmann Fold, Malate dehydrogenase, Ascaris suum; OXIDOREDUCTASE
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

1o0s__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

1o0s__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

1o0s__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）44.65 Å
Rg (electron density)44.00 Å
Total Rg44.38 Å
Atom count19240
Residues2388
Excluded volume343130 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 1o0s__assembly_1__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (4)

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6. Fold Classification (SCOP + CATH) 12 domains

SCOP 2.08 (4 domains)

Domain ID domain_idd1o0sa1
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.2 — NAD(P)-binding Rossmann-fold domains
Superfamily Superfamily superfamilyc.2.1 — NAD(P)-binding Rossmann-fold domains
Family Family familyc.2.1.7 — Aminoacid dehydrogenase-like, C-terminal domain
Domain ID domain_idd1o0sa2
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.58 — Aminoacid dehydrogenase-like, N-terminal domain
Superfamily Superfamily superfamilyc.58.1 — Aminoacid dehydrogenase-like, N-terminal domain
Family Family familyc.58.1.3 — Malic enzyme N-domain
Domain ID domain_idd1o0sb1
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.2 — NAD(P)-binding Rossmann-fold domains
Superfamily Superfamily superfamilyc.2.1 — NAD(P)-binding Rossmann-fold domains
Family Family familyc.2.1.7 — Aminoacid dehydrogenase-like, C-terminal domain
Domain ID domain_idd1o0sb2
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.58 — Aminoacid dehydrogenase-like, N-terminal domain
Superfamily Superfamily superfamilyc.58.1 — Aminoacid dehydrogenase-like, N-terminal domain
Family Family familyc.58.1.3 — Malic enzyme N-domain

CATH v4.4 (8 domains)

Domain ID domain_id1o0sA01
Class class6 — Special
Architecture architecture20 — Other non-globular
Topology topology310 — arginine biosynthesis bifunctional protein fold
Homologous superfamily homologous superfamily10 —
Domain ID domain_id1o0sA02
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology1370 — Hemocyanin, N-terminal domain
Homologous superfamily homologous superfamily30 —
Domain ID domain_id1o0sA03
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily10380 — Malic enzyme, N-terminal domain
Domain ID domain_id1o0sA04
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily720 — NAD(P)-binding Rossmann-like Domain
Domain ID domain_id1o0sB01
Class class6 — Special
Architecture architecture20 — Other non-globular
Topology topology310 — arginine biosynthesis bifunctional protein fold
Homologous superfamily homologous superfamily10 —
Domain ID domain_id1o0sB02
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology1370 — Hemocyanin, N-terminal domain
Homologous superfamily homologous superfamily30 —
Domain ID domain_id1o0sB03
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily10380 — Malic enzyme, N-terminal domain
Domain ID domain_id1o0sB04
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily720 — NAD(P)-binding Rossmann-like Domain
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7. Citations (2)