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1or7

Crystal Structure of Escherichia coli sigmaE with the Cytoplasmic Domain of its Anti-sigma RseA

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

RNA polymerase sigma-E factor

Escherichia coli

UniProt P0AGB6

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 2 Sigma-E factor negative regulatory protein × 1 （P0AFX7） water × 2 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 2 Sigma-E factor negative regulatory protein × 1 （P0AFX7） water × 2 Consistent with protein count
3 Protein heterocomplex Heteromer Protein 4 Sigma-E factor negative regulatory protein × 2 （P0AFX7） water × 4 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1or7 1or7 1or7 2h27 2h27 5or5 6jbq

7 assemblies

View Construct and Data Evidence
UniProt name RPOE_ECOLI
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 4–194； UniProt 1–191 Author chain B； PDBConstruct 4–194； UniProt 1–191

Sigma-E factor negative regulatory protein

Escherichia coli

UniProt P0AFX7

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 2 RNA polymerase sigma-E factor × 1 （P0AGB6） water × 2 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 2 RNA polymerase sigma-E factor × 1 （P0AGB6） water × 2 Consistent with protein count
3 Protein heterocomplex Heteromer Protein 4 RNA polymerase sigma-E factor × 2 （P0AGB6） water × 4 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1or7 1or7 1or7 3m4w 3m4w

5 assemblies

View Construct and Data Evidence
UniProt name RSEA_ECOLI
Isoform —
PDB entities 2
Chains and sequence ranges Author chain C； PDBConstruct 1–90； UniProt 1–90 Author chain F； PDBConstruct 1–90； UniProt 1–90

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id1or7
Deposition date deposition_date2003-03-12
Structure title titleCrystal Structure of Escherichia coli sigmaE with the Cytoplasmic Domain of its Anti-sigma RseA
Keywords keywordsregulation, DNA-BINDING, TRANSMEMBRANE, TRANSCRIPTION; TRANSCRIPTION
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

1or7__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

1or7__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

1or7__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）20.83 Å
Rg (electron density)19.79 Å
Total Rg20.64 Å
Atom count1972
Residues247
Excluded volume34862 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 1or7__assembly_1__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 1or7__assembly_2__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
3 1 1or7__assembly_3__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

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6. Fold Classification (SCOP + CATH) 14 domains

SCOP 2.08 (8 domains)

Domain ID domain_idd1or7a1
Class classa — All alpha proteins
Fold Fold folda.4 — DNA/RNA-binding 3-helical bundle
Superfamily Superfamily superfamilya.4.13 — Sigma3 and sigma4 domains of RNA polymerase sigma factors
Family Family familya.4.13.2 — Sigma4 domain
Domain ID domain_idd1or7a2
Class classa — All alpha proteins
Fold Fold folda.177 — Sigma2 domain of RNA polymerase sigma factors
Superfamily Superfamily superfamilya.177.1 — Sigma2 domain of RNA polymerase sigma factors
Family Family familya.177.1.1 — Sigma2 domain of RNA polymerase sigma factors
Domain ID domain_idd1or7a3
Class classl — Artifacts
Fold Fold foldl.1 — Tags
Superfamily Superfamily superfamilyl.1.1 — Tags
Family Family familyl.1.1.1 — Tags
Domain ID domain_idd1or7b1
Class classa — All alpha proteins
Fold Fold folda.4 — DNA/RNA-binding 3-helical bundle
Superfamily Superfamily superfamilya.4.13 — Sigma3 and sigma4 domains of RNA polymerase sigma factors
Family Family familya.4.13.2 — Sigma4 domain
Domain ID domain_idd1or7b2
Class classa — All alpha proteins
Fold Fold folda.177 — Sigma2 domain of RNA polymerase sigma factors
Superfamily Superfamily superfamilya.177.1 — Sigma2 domain of RNA polymerase sigma factors
Family Family familya.177.1.1 — Sigma2 domain of RNA polymerase sigma factors
Domain ID domain_idd1or7b3
Class classl — Artifacts
Fold Fold foldl.1 — Tags
Superfamily Superfamily superfamilyl.1.1 — Tags
Family Family familyl.1.1.1 — Tags
Domain ID domain_idd1or7c_
Class classa — All alpha proteins
Fold Fold folda.180 — N-terminal, cytoplasmic domain of anti-sigmaE factor RseA
Superfamily Superfamily superfamilya.180.1 — N-terminal, cytoplasmic domain of anti-sigmaE factor RseA
Family Family familya.180.1.1 — N-terminal, cytoplasmic domain of anti-sigmaE factor RseA
Domain ID domain_idd1or7f_
Class classa — All alpha proteins
Fold Fold folda.180 — N-terminal, cytoplasmic domain of anti-sigmaE factor RseA
Superfamily Superfamily superfamilya.180.1 — N-terminal, cytoplasmic domain of anti-sigmaE factor RseA
Family Family familya.180.1.1 — N-terminal, cytoplasmic domain of anti-sigmaE factor RseA

CATH v4.4 (6 domains)

Domain ID domain_id1or7A01
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology1740 — Rna Polymerase Sigma Factor; Chain: A
Homologous superfamily homologous superfamily10 — RNA polymerase sigma factor, region 2, helix turn helix motif
Domain ID domain_id1or7A02
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology10 — Arc Repressor Mutant, subunit A
Homologous superfamily homologous superfamily10 — Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Domain ID domain_id1or7B01
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology1740 — Rna Polymerase Sigma Factor; Chain: A
Homologous superfamily homologous superfamily10 — RNA polymerase sigma factor, region 2, helix turn helix motif
Domain ID domain_id1or7B02
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology10 — Arc Repressor Mutant, subunit A
Homologous superfamily homologous superfamily10 — Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Domain ID domain_id1or7C00
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology10 — Arc Repressor Mutant, subunit A
Homologous superfamily homologous superfamily880 — Anti sigma-E protein RseA, N-terminal domain
Domain ID domain_id1or7F00
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology10 — Arc Repressor Mutant, subunit A
Homologous superfamily homologous superfamily880 — Anti sigma-E protein RseA, N-terminal domain
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7. Citations (1)