1p75

Crystal structure of EHV4-TK complexed with TP5A

Method: X-RAY DIFFRACTION Dmax: 135.6 Å Quality: GOOD

SAXS 散射曲线 SAXS Profile

SAXS profile for 1p75

P(r) 距离分布 P(r) Distribution

P(r) distribution for 1p75
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1. 结构基本信息 1. Structure Basics

条目编号 entry_id1p75
沉积日期 deposition_date2003-04-30
结构标题 titleCrystal structure of EHV4-TK complexed with TP5A
关键词 keywordsP-loop, Lid, TRANSFERASE; TRANSFERASE
实验方法 methodX-RAY DIFFRACTION

2. SAXS 参数 (CRYSOL 理论计算) 2. SAXS Parameters (CRYSOL)

回转半径 Rg (Guinier) rg_guinier40.45
回转半径 Rg (电子) rg_electron40.14
零角强度 I(0) i0365404000.00
分子量 molecular_weight149770.0 kDa
排除体积 excluded_volume184530 ų
包络体积 envelope_volume240650 ų
水化壳体积 shell_volume50296 ų
包络直径 envelope_diameter139.5
壳层 Rg shell_rg45.32
包络 Rg envelope_rg39.79
形状 Rg shape_rg40.14
总 Rg total_rg40.39
总原子数 total_atoms10457
残基数 n_residues1322
球谐函数阶数 n_harmonics20
q 范围 q_range— – 0.5000 −1
数据点数 n_points101
壳层类型 shell_typedirectional
溶剂电子密度 solvent_density0.3340 e/ų
壳层衬度 contrast_shell0.0300 e/ų
CRYSOL 版本 crysol_version4.1.3

3. P(r) 距离分布 (GNOM 反演) 3. P(r) Analysis (GNOM)

最大尺寸 Dmax dmax135.6
Rg (实空间) rg_real40.62
Rg 误差 (实空间) rg_real_error1.35
I(0) (实空间) i0_real3.6540e+08
I(0) 误差 (实空间) i0_real_error6.6600e+06
Rg (倒空间) rg_reciprocal40.45
I(0) (倒空间) i0_reciprocal365300000.0000
解质量估计 total_estimate0.8443
解质量评级 solution_quality GOOD a GOOD solution
P(r) 峰数 n_peaks1
主峰位置 r_peak_primary38.2
偏度 Skewness skewness0.413
峰度 Kurtosis kurtosis-0.597
角度范围 angular_range— – 0.1950 −1
当前正则化参数 α current_alpha0.0000
最高正则化参数 α highest_alpha83870000.0000
实空间数据点数 n_real_points40
GNOM 版本 gnom_version4.1.3
质量判据 quality_criteria AN1: 0.000; Oscil: 0.781; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.829; Smooth: 0.800

4. 晶体学与实验 4. Crystallography & Experiment

5. 实体与聚合体信息 (4)

6. 折叠分类 (SCOP + CATH) 12 domains

SCOP 2.08 (8 domains)

结构域编号 domain_idd1p75a1
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamilyc.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family familyc.37.1.1 — Nucleotide and nucleoside kinases
结构域编号 domain_idd1p75a2
类 Class classl — Artifacts
折叠类型 Fold foldl.1 — Tags
超家族 Superfamily superfamilyl.1.1 — Tags
家族 Family familyl.1.1.1 — Tags
结构域编号 domain_idd1p75b1
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamilyc.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family familyc.37.1.1 — Nucleotide and nucleoside kinases
结构域编号 domain_idd1p75b2
类 Class classl — Artifacts
折叠类型 Fold foldl.1 — Tags
超家族 Superfamily superfamilyl.1.1 — Tags
家族 Family familyl.1.1.1 — Tags
结构域编号 domain_idd1p75c1
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamilyc.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family familyc.37.1.1 — Nucleotide and nucleoside kinases
结构域编号 domain_idd1p75c2
类 Class classl — Artifacts
折叠类型 Fold foldl.1 — Tags
超家族 Superfamily superfamilyl.1.1 — Tags
家族 Family familyl.1.1.1 — Tags
结构域编号 domain_idd1p75d1
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamilyc.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family familyc.37.1.1 — Nucleotide and nucleoside kinases
结构域编号 domain_idd1p75d2
类 Class classl — Artifacts
折叠类型 Fold foldl.1 — Tags
超家族 Superfamily superfamilyl.1.1 — Tags
家族 Family familyl.1.1.1 — Tags

CATH v4.4 (4 domains)

结构域编号 domain_id1p75A00
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily300 — P-loop containing nucleotide triphosphate hydrolases
结构域编号 domain_id1p75B00
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily300 — P-loop containing nucleotide triphosphate hydrolases
结构域编号 domain_id1p75C00
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily300 — P-loop containing nucleotide triphosphate hydrolases
结构域编号 domain_id1p75D00
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily300 — P-loop containing nucleotide triphosphate hydrolases

7. 引用文献 (1)

8. 文件与曲线 (10)