1pcf

HUMAN TRANSCRIPTIONAL COACTIVATOR PC4 C-TERMINAL DOMAIN

Method: X-RAY DIFFRACTION D_max: 91.3 Å Quality: REASONABLE

SAXS 散射曲线 SAXS Profile

P(r) 距离分布 P(r) Distribution

下载 Download SAXS (.dat) P(r) (.pr.out) CIF

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1. 结构基本信息 1. Structure Basics

条目编号 entry_id	1pcf
沉积日期 deposition_date	1997-09-09
结构标题 title	HUMAN TRANSCRIPTIONAL COACTIVATOR PC4 C-TERMINAL DOMAIN
关键词 keywords	TRANSCRIPTION, TRANSCRIPTIONAL COFACTOR, TRANSCRIPTIONAL CO-ACTIVATOR, SSDNA BINDING, NUCLEAR PROTEIN; TRANSCRIPTION
实验方法 method	X-RAY DIFFRACTION

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2. SAXS 参数 (CRYSOL 理论计算) 2. SAXS Parameters (CRYSOL)

回转半径 Rg (Guinier) rg_guinier	28.55 Å
回转半径 Rg (电子) rg_electron	27.54 Å
零角强度 I(0) i0	63307800.00
分子量 molecular_weight	62184.0 kDa
排除体积 excluded_volume	78171 Å³
包络体积 envelope_volume	104280 Å³
水化壳体积 shell_volume	31470 Å³
包络直径 envelope_diameter	97.8 Å
壳层 Rg shell_rg	34.75 Å
包络 Rg envelope_rg	27.52 Å
形状 Rg shape_rg	27.50 Å
总 Rg total_rg	28.49 Å
总原子数 total_atoms	4360
残基数 n_residues	528
球谐函数阶数 n_harmonics	20
q 范围 q_range	— – 0.5000 Å⁻¹
数据点数 n_points	101
壳层类型 shell_type	directional
溶剂电子密度 solvent_density	0.3340 e/Å³
壳层衬度 contrast_shell	0.0300 e/Å³
CRYSOL 版本 crysol_version	4.1.3

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3. P(r) 距离分布 (GNOM 反演) 3. P(r) Analysis (GNOM)

最大尺寸 Dmax dmax	91.3 Å
Rg (实空间) rg_real	28.45 Å
Rg 误差 (实空间) rg_real_error	0.68 Å
I(0) (实空间) i0_real	6.3310e+07
I(0) 误差 (实空间) i0_real_error	1.0000e+06
Rg (倒空间) rg_reciprocal	28.50 Å
I(0) (倒空间) i0_reciprocal	63310000.0000
解质量估计 total_estimate	0.6503
解质量评级 solution_quality	REASONABLE a REASONABLE solution
P(r) 峰数 n_peaks	2
主峰位置 r_peak_primary	37.5 Å
偏度 Skewness skewness	0.182
峰度 Kurtosis kurtosis	-0.471
角度范围 angular_range	— – 0.2800 Å⁻¹
当前正则化参数 α current_alpha	0.0000
最高正则化参数 α highest_alpha	12990000.0000
实空间数据点数 n_real_points	57
GNOM 版本 gnom_version	4.1.3
质量判据 quality_criteria	AN1: 0.000; Oscil: 0.909; Stabil: 0.998; Sysdev: 0.242; Positv: 1.000; Valcen: 1.000; Smooth: 0.000

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4. 晶体学与实验 4. Crystallography & Experiment

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5. 实体与聚合体信息 (2)

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6. 折叠分类 (SCOP + CATH) 24 domains

SCOP 2.08 (16 domains)

结构域编号 domain_id	d1pcfa1
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.18 — ssDNA-binding transcriptional regulator domain
超家族 Superfamily superfamily	d.18.1 — ssDNA-binding transcriptional regulator domain
家族 Family family	d.18.1.1 — Transcriptional coactivator PC4 C-terminal domain

结构域编号 domain_id	d1pcfa2
类 Class class	l — Artifacts
折叠类型 Fold fold	l.1 — Tags
超家族 Superfamily superfamily	l.1.1 — Tags
家族 Family family	l.1.1.1 — Tags

结构域编号 domain_id	d1pcfb1
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.18 — ssDNA-binding transcriptional regulator domain
超家族 Superfamily superfamily	d.18.1 — ssDNA-binding transcriptional regulator domain
家族 Family family	d.18.1.1 — Transcriptional coactivator PC4 C-terminal domain

结构域编号 domain_id	d1pcfb2
类 Class class	l — Artifacts
折叠类型 Fold fold	l.1 — Tags
超家族 Superfamily superfamily	l.1.1 — Tags
家族 Family family	l.1.1.1 — Tags

结构域编号 domain_id	d1pcfc1
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.18 — ssDNA-binding transcriptional regulator domain
超家族 Superfamily superfamily	d.18.1 — ssDNA-binding transcriptional regulator domain
家族 Family family	d.18.1.1 — Transcriptional coactivator PC4 C-terminal domain

结构域编号 domain_id	d1pcfc2
类 Class class	l — Artifacts
折叠类型 Fold fold	l.1 — Tags
超家族 Superfamily superfamily	l.1.1 — Tags
家族 Family family	l.1.1.1 — Tags

结构域编号 domain_id	d1pcfd1
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.18 — ssDNA-binding transcriptional regulator domain
超家族 Superfamily superfamily	d.18.1 — ssDNA-binding transcriptional regulator domain
家族 Family family	d.18.1.1 — Transcriptional coactivator PC4 C-terminal domain

结构域编号 domain_id	d1pcfd2
类 Class class	l — Artifacts
折叠类型 Fold fold	l.1 — Tags
超家族 Superfamily superfamily	l.1.1 — Tags
家族 Family family	l.1.1.1 — Tags

结构域编号 domain_id	d1pcfe1
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.18 — ssDNA-binding transcriptional regulator domain
超家族 Superfamily superfamily	d.18.1 — ssDNA-binding transcriptional regulator domain
家族 Family family	d.18.1.1 — Transcriptional coactivator PC4 C-terminal domain

结构域编号 domain_id	d1pcfe2
类 Class class	l — Artifacts
折叠类型 Fold fold	l.1 — Tags
超家族 Superfamily superfamily	l.1.1 — Tags
家族 Family family	l.1.1.1 — Tags

结构域编号 domain_id	d1pcff1
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.18 — ssDNA-binding transcriptional regulator domain
超家族 Superfamily superfamily	d.18.1 — ssDNA-binding transcriptional regulator domain
家族 Family family	d.18.1.1 — Transcriptional coactivator PC4 C-terminal domain

结构域编号 domain_id	d1pcff2
类 Class class	l — Artifacts
折叠类型 Fold fold	l.1 — Tags
超家族 Superfamily superfamily	l.1.1 — Tags
家族 Family family	l.1.1.1 — Tags

结构域编号 domain_id	d1pcfg1
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.18 — ssDNA-binding transcriptional regulator domain
超家族 Superfamily superfamily	d.18.1 — ssDNA-binding transcriptional regulator domain
家族 Family family	d.18.1.1 — Transcriptional coactivator PC4 C-terminal domain

结构域编号 domain_id	d1pcfg2
类 Class class	l — Artifacts
折叠类型 Fold fold	l.1 — Tags
超家族 Superfamily superfamily	l.1.1 — Tags
家族 Family family	l.1.1.1 — Tags

结构域编号 domain_id	d1pcfh1
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.18 — ssDNA-binding transcriptional regulator domain
超家族 Superfamily superfamily	d.18.1 — ssDNA-binding transcriptional regulator domain
家族 Family family	d.18.1.1 — Transcriptional coactivator PC4 C-terminal domain

结构域编号 domain_id	d1pcfh2
类 Class class	l — Artifacts
折叠类型 Fold fold	l.1 — Tags
超家族 Superfamily superfamily	l.1.1 — Tags
家族 Family family	l.1.1.1 — Tags

CATH v4.4 (8 domains)

结构域编号 domain_id	1pcfA00
类 Class class	2 — Mainly Beta
架构 Architecture architecture	30 — Roll
拓扑 Topology topology	31 — Transcriptional Co-activator pc4; Chain A
同源超家族 H-superfamily homologous superfamily	10 — Transcriptional Coactivator Pc4; Chain A

结构域编号 domain_id	1pcfB00
类 Class class	2 — Mainly Beta
架构 Architecture architecture	30 — Roll
拓扑 Topology topology	31 — Transcriptional Co-activator pc4; Chain A
同源超家族 H-superfamily homologous superfamily	10 — Transcriptional Coactivator Pc4; Chain A

结构域编号 domain_id	1pcfC00
类 Class class	2 — Mainly Beta
架构 Architecture architecture	30 — Roll
拓扑 Topology topology	31 — Transcriptional Co-activator pc4; Chain A
同源超家族 H-superfamily homologous superfamily	10 — Transcriptional Coactivator Pc4; Chain A

结构域编号 domain_id	1pcfD00
类 Class class	2 — Mainly Beta
架构 Architecture architecture	30 — Roll
拓扑 Topology topology	31 — Transcriptional Co-activator pc4; Chain A
同源超家族 H-superfamily homologous superfamily	10 — Transcriptional Coactivator Pc4; Chain A

结构域编号 domain_id	1pcfE00
类 Class class	2 — Mainly Beta
架构 Architecture architecture	30 — Roll
拓扑 Topology topology	31 — Transcriptional Co-activator pc4; Chain A
同源超家族 H-superfamily homologous superfamily	10 — Transcriptional Coactivator Pc4; Chain A

结构域编号 domain_id	1pcfF00
类 Class class	2 — Mainly Beta
架构 Architecture architecture	30 — Roll
拓扑 Topology topology	31 — Transcriptional Co-activator pc4; Chain A
同源超家族 H-superfamily homologous superfamily	10 — Transcriptional Coactivator Pc4; Chain A

结构域编号 domain_id	1pcfG00
类 Class class	2 — Mainly Beta
架构 Architecture architecture	30 — Roll
拓扑 Topology topology	31 — Transcriptional Co-activator pc4; Chain A
同源超家族 H-superfamily homologous superfamily	10 — Transcriptional Coactivator Pc4; Chain A

结构域编号 domain_id	1pcfH00
类 Class class	2 — Mainly Beta
架构 Architecture architecture	30 — Roll
拓扑 Topology topology	31 — Transcriptional Co-activator pc4; Chain A
同源超家族 H-superfamily homologous superfamily	10 — Transcriptional Coactivator Pc4; Chain A

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7. 引用文献 (1)

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晶胞边长 a length_a	41.283 Å
晶胞边长 b length_b	67.814 Å
晶胞边长 c length_c	67.170 Å
晶胞夹角 α angle_alpha	87.69 °
晶胞夹角 β angle_beta	84.37 °
晶胞夹角 γ angle_gamma	85.79 °
晶胞分子数 Z z_pdb	8

空间群 space_group	P 1
空间群编号 int_tables_number	1
晶系 crystal_system	—

分辨率 resolution	1.740 Å
最低分辨率 resolution_low	20.000 Å
R 因子 r_factor	—
R_work r_work	0.1970
R_free r_free	0.2330

描述 description	TRANSCRIPTIONAL COACTIVATOR PC4
分子量 formula_weight	7784.0 kDa
来源方法 src_method	man
拷贝数 entity_count	8

聚合体类型 type	polypeptide(L)
链编号 strand_id	A,B,C,D,E,F,G,H
原子数 atom_count	4794

HUMAN TRANSCRIPTIONAL COACTIVATOR PC4 C-TERMINAL DOMAIN

SAXS 散射曲线 SAXS Profile

P(r) 距离分布 P(r) Distribution

1. 结构基本信息 1. Structure Basics

2. SAXS 参数 (CRYSOL 理论计算) 2. SAXS Parameters (CRYSOL)

3. P(r) 距离分布 (GNOM 反演) 3. P(r) Analysis (GNOM)

4. 晶体学与实验 4. Crystallography & Experiment

晶胞参数 Unit Cell

对称性 Symmetry

精修参数 Refinement

衍射实验 Diffraction

5. 实体与聚合体信息 (2)

Entity 1 polymer

聚合体 Polymer

来源 Source

Entity 2 water

6. 折叠分类 (SCOP + CATH) 24 domains

SCOP 2.08 (16 domains)

CATH v4.4 (8 domains)

7. 引用文献 (1)

8. 文件与曲线 (10)

Files (7)

Curves (3)

来源生物 organism	Homo sapiens
通用名 common_name	human
NCBI 分类编号 ncbi_taxonomy_id	9606
宿主生物 host_organism	Escherichia coli BL21(DE3)

描述 description	water
分子量 formula_weight	18.0 kDa
来源方法 src_method	nat
拷贝数 entity_count	434

fit	/app/data/saxs_computation/pc/1pcf/1pcf.fit
pddf	/app/data/pr_computation/pc/1pcf/1pcf.pr.out
profile	/app/data/saxs_computation/pc/1pcf/1pcf.dat