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1q4q

Crystal structure of a DIAP1-Dronc complex

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Apoptosis 1 inhibitor

Drosophila melanogaster

UniProt Q24306

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 2 Nedd2-like caspase CG8091-PA × 1 （Q9XYF4） ZINC ION × 1 water × 2 Consistent with protein count
10 Protein heterocomplex Heteromer Protein 2 Nedd2-like caspase CG8091-PA × 1 （Q9XYF4） ZINC ION × 1 water × 2 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 2 Nedd2-like caspase CG8091-PA × 1 （Q9XYF4） ZINC ION × 1 water × 2 Consistent with protein count
3 Protein heterocomplex Heteromer Protein 2 Nedd2-like caspase CG8091-PA × 1 （Q9XYF4） ZINC ION × 1 water × 2 Consistent with protein count
4 Protein heterocomplex Heteromer Protein 2 Nedd2-like caspase CG8091-PA × 1 （Q9XYF4） ZINC ION × 1 water × 2 Consistent with protein count
5 Protein heterocomplex Heteromer Protein 2 Nedd2-like caspase CG8091-PA × 1 （Q9XYF4） ZINC ION × 1 water × 2 Consistent with protein count
6 Protein heterocomplex Heteromer Protein 2 Nedd2-like caspase CG8091-PA × 1 （Q9XYF4） ZINC ION × 1 water × 2 Consistent with protein count
7 Protein heterocomplex Heteromer Protein 2 Nedd2-like caspase CG8091-PA × 1 （Q9XYF4） ZINC ION × 1 water × 2 Consistent with protein count
8 Protein heterocomplex Heteromer Protein 2 Nedd2-like caspase CG8091-PA × 1 （Q9XYF4） ZINC ION × 1 water × 2 Consistent with protein count
9 Protein heterocomplex Heteromer Protein 2 Nedd2-like caspase CG8091-PA × 1 （Q9XYF4） ZINC ION × 1 water × 2 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1jd4 1jd4 3siq 3siq 3siq 3siq 3siq 3siq

8 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1jd5 1jd6 1q4q 1q4q 1q4q 1q4q 1q4q 1q4q 1q4q 1q4q 1q4q 1q4q

16 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name IAP1_DROME
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–124； UniProt 201–323 Author chain B； PDBConstruct 1–124； UniProt 201–323 Author chain C； PDBConstruct 1–124； UniProt 201–323 Author chain D； PDBConstruct 1–124； UniProt 201–323 Author chain E； PDBConstruct 1–124； UniProt 201–323 Author chain F； PDBConstruct 1–124； UniProt 201–323 Author chain G； PDBConstruct 1–124； UniProt 201–323 Author chain H； PDBConstruct 1–124； UniProt 201–323 Author chain I； PDBConstruct 1–124； UniProt 201–323 Author chain J； PDBConstruct 1–124； UniProt 201–323

Nedd2-like caspase CG8091-PA

OrganismNot specified

UniProt Q9XYF4

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 2 Apoptosis 1 inhibitor × 1 （Q24306） ZINC ION × 1 water × 2 Consistent with protein count
10 Protein heterocomplex Heteromer Protein 2 Apoptosis 1 inhibitor × 1 （Q24306） ZINC ION × 1 water × 2 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 2 Apoptosis 1 inhibitor × 1 （Q24306） ZINC ION × 1 water × 2 Consistent with protein count
3 Protein heterocomplex Heteromer Protein 2 Apoptosis 1 inhibitor × 1 （Q24306） ZINC ION × 1 water × 2 Consistent with protein count
4 Protein heterocomplex Heteromer Protein 2 Apoptosis 1 inhibitor × 1 （Q24306） ZINC ION × 1 water × 2 Consistent with protein count
5 Protein heterocomplex Heteromer Protein 2 Apoptosis 1 inhibitor × 1 （Q24306） ZINC ION × 1 water × 2 Consistent with protein count
6 Protein heterocomplex Heteromer Protein 2 Apoptosis 1 inhibitor × 1 （Q24306） ZINC ION × 1 water × 2 Consistent with protein count
7 Protein heterocomplex Heteromer Protein 2 Apoptosis 1 inhibitor × 1 （Q24306） ZINC ION × 1 water × 2 Consistent with protein count
8 Protein heterocomplex Heteromer Protein 2 Apoptosis 1 inhibitor × 1 （Q24306） ZINC ION × 1 water × 2 Consistent with protein count
9 Protein heterocomplex Heteromer Protein 2 Apoptosis 1 inhibitor × 1 （Q24306） ZINC ION × 1 water × 2 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
2fp3

1 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1q4q 1q4q 1q4q 1q4q 1q4q 1q4q 1q4q 1q4q 1q4q 1q4q 3j9k 8y6q

12 assemblies

View Construct and Data Evidence
UniProt name ICENC_DROME
Isoform —
PDB entities 2
Chains and sequence ranges Author chain K； PDBConstruct 1–12； UniProt 114–125 Author chain L； PDBConstruct 1–12； UniProt 114–125 Author chain M； PDBConstruct 1–12； UniProt 114–125 Author chain N； PDBConstruct 1–12； UniProt 114–125 Author chain O； PDBConstruct 1–12； UniProt 114–125 Author chain P； PDBConstruct 1–12； UniProt 114–125 Author chain Q； PDBConstruct 1–12； UniProt 114–125 Author chain R； PDBConstruct 1–12； UniProt 114–125 Author chain S； PDBConstruct 1–12； UniProt 114–125 Author chain T； PDBConstruct 1–12； UniProt 114–125

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id1q4q
Deposition date deposition_date2003-08-04
Structure title titleCrystal structure of a DIAP1-Dronc complex
Keywords keywordscaspase, IAP, ubiquitination, apoptosis, APOPTOSIS INHIBITOR; APOPTOSIS INHIBITOR
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

1q4q__assembly_10__model_1

Assembly 10 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

1q4q__assembly_10__model_1 | I(q)

10-2 10-1 105 106 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

1q4q__assembly_10__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）13.89 Å
Rg (electron density)12.70 Å
Total Rg14.06 Å
Atom count833
Residues101
Excluded volume14798 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 1q4q__assembly_1__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 1q4q__assembly_2__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
3 1 1q4q__assembly_3__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
4 1 1q4q__assembly_4__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
5 1 1q4q__assembly_5__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
6 1 1q4q__assembly_6__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
7 1 1q4q__assembly_7__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
8 1 1q4q__assembly_8__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
9 1 1q4q__assembly_9__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
10 1 1q4q__assembly_10__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (4)

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6. Fold Classification (SCOP + CATH) 20 domains

SCOP 2.08 (10 domains)

Domain ID domain_idd1q4qa_
Class classg — Small proteins
Fold Fold foldg.52 — Inhibitor of apoptosis (IAP) repeat
Superfamily Superfamily superfamilyg.52.1 — Inhibitor of apoptosis (IAP) repeat
Family Family familyg.52.1.1 — Inhibitor of apoptosis (IAP) repeat
Domain ID domain_idd1q4qb_
Class classg — Small proteins
Fold Fold foldg.52 — Inhibitor of apoptosis (IAP) repeat
Superfamily Superfamily superfamilyg.52.1 — Inhibitor of apoptosis (IAP) repeat
Family Family familyg.52.1.1 — Inhibitor of apoptosis (IAP) repeat
Domain ID domain_idd1q4qc_
Class classg — Small proteins
Fold Fold foldg.52 — Inhibitor of apoptosis (IAP) repeat
Superfamily Superfamily superfamilyg.52.1 — Inhibitor of apoptosis (IAP) repeat
Family Family familyg.52.1.1 — Inhibitor of apoptosis (IAP) repeat
Domain ID domain_idd1q4qd_
Class classg — Small proteins
Fold Fold foldg.52 — Inhibitor of apoptosis (IAP) repeat
Superfamily Superfamily superfamilyg.52.1 — Inhibitor of apoptosis (IAP) repeat
Family Family familyg.52.1.1 — Inhibitor of apoptosis (IAP) repeat
Domain ID domain_idd1q4qe_
Class classg — Small proteins
Fold Fold foldg.52 — Inhibitor of apoptosis (IAP) repeat
Superfamily Superfamily superfamilyg.52.1 — Inhibitor of apoptosis (IAP) repeat
Family Family familyg.52.1.1 — Inhibitor of apoptosis (IAP) repeat
Domain ID domain_idd1q4qf_
Class classg — Small proteins
Fold Fold foldg.52 — Inhibitor of apoptosis (IAP) repeat
Superfamily Superfamily superfamilyg.52.1 — Inhibitor of apoptosis (IAP) repeat
Family Family familyg.52.1.1 — Inhibitor of apoptosis (IAP) repeat
Domain ID domain_idd1q4qg_
Class classg — Small proteins
Fold Fold foldg.52 — Inhibitor of apoptosis (IAP) repeat
Superfamily Superfamily superfamilyg.52.1 — Inhibitor of apoptosis (IAP) repeat
Family Family familyg.52.1.1 — Inhibitor of apoptosis (IAP) repeat
Domain ID domain_idd1q4qh_
Class classg — Small proteins
Fold Fold foldg.52 — Inhibitor of apoptosis (IAP) repeat
Superfamily Superfamily superfamilyg.52.1 — Inhibitor of apoptosis (IAP) repeat
Family Family familyg.52.1.1 — Inhibitor of apoptosis (IAP) repeat
Domain ID domain_idd1q4qi_
Class classg — Small proteins
Fold Fold foldg.52 — Inhibitor of apoptosis (IAP) repeat
Superfamily Superfamily superfamilyg.52.1 — Inhibitor of apoptosis (IAP) repeat
Family Family familyg.52.1.1 — Inhibitor of apoptosis (IAP) repeat
Domain ID domain_idd1q4qj_
Class classg — Small proteins
Fold Fold foldg.52 — Inhibitor of apoptosis (IAP) repeat
Superfamily Superfamily superfamilyg.52.1 — Inhibitor of apoptosis (IAP) repeat
Family Family familyg.52.1.1 — Inhibitor of apoptosis (IAP) repeat

CATH v4.4 (10 domains)

Domain ID domain_id1q4qA00
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology1170 — Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A
Homologous superfamily homologous superfamily10 — Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A
Domain ID domain_id1q4qB00
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology1170 — Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A
Homologous superfamily homologous superfamily10 — Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A
Domain ID domain_id1q4qC00
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology1170 — Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A
Homologous superfamily homologous superfamily10 — Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A
Domain ID domain_id1q4qD00
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology1170 — Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A
Homologous superfamily homologous superfamily10 — Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A
Domain ID domain_id1q4qE00
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology1170 — Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A
Homologous superfamily homologous superfamily10 — Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A
Domain ID domain_id1q4qF00
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology1170 — Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A
Homologous superfamily homologous superfamily10 — Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A
Domain ID domain_id1q4qG00
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology1170 — Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A
Homologous superfamily homologous superfamily10 — Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A
Domain ID domain_id1q4qH00
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology1170 — Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A
Homologous superfamily homologous superfamily10 — Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A
Domain ID domain_id1q4qI00
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology1170 — Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A
Homologous superfamily homologous superfamily10 — Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A
Domain ID domain_id1q4qJ00
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology1170 — Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A
Homologous superfamily homologous superfamily10 — Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A
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7. Citations (1)