1ryy

Acetobacter turbidans alpha-amino acid ester hydrolase Y206A mutant

Method: X-RAY DIFFRACTION

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1. 蛋白身份与相关结构 Protein Identity & Related Structures

alpha-amino acid ester hydrolase

Acetobacter pasteurianus

当前结构中的状态

Assembly	物理组成	蛋白状态	分子拷贝数	共同组分	数据核对
1	蛋白同源多聚体	同源多聚体	蛋白 4	water × 4	与蛋白数一致
2	蛋白同源多聚体	同源多聚体	蛋白 4	water × 4	与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据

UniProt名称	Q8VRK8_ACEPA
Isoform	—
PDB实体	1
链与序列区间	作者链 A； PDB构建体 1–627； UniProt 41–667 作者链 B； PDB构建体 1–627； UniProt 41–667 作者链 C； PDB构建体 1–627； UniProt 41–667 作者链 D； PDB构建体 1–627； UniProt 41–667 作者链 E； PDB构建体 1–627； UniProt 41–667 作者链 F； PDB构建体 1–627； UniProt 41–667 作者链 G； PDB构建体 1–627； UniProt 41–667 作者链 H； PDB构建体 1–627； UniProt 41–667

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。

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2. 结构基本信息 2. Structure Basics

条目编号 entry_id	1ryy
沉积日期 deposition_date	2003-12-23
结构标题 title	Acetobacter turbidans alpha-amino acid ester hydrolase Y206A mutant
关键词 keywords	alpha/beta hydrolase fold, jellyroll fold, HYDROLASE; HYDROLASE
实验方法 method	X-RAY DIFFRACTION

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3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

1ryy__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

1ryy__assembly_1__model_1 | I(q)

100 个绘图点；横轴和纵轴均采用对数尺度。

1ryy__assembly_1__model_1 | P(r) · Pending

P(r) 将按相同 assembly/model 分别计算和展示。

Rg（Guinier）	40.22 Å
Rg（电子密度）	39.43 Å
总 Rg	39.97 Å
原子数	19344
残基数	2448
排除体积	340550 Å³
最大 q	0.500 Å⁻¹

Assembly	Model	结构单元	聚集说明	状态	CRYSOL	操作
1	1	`1ryy__assembly_1__model_1`	tetrameric （4）	成功	4.1.3-1-20251215 (887e7ef)	查看下载
2	1	`1ryy__assembly_2__model_1`	tetrameric （4）	成功	4.1.3-1-20251215 (887e7ef)	查看下载

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4. 晶体学与实验 4. Crystallography & Experiment

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5. 实体与聚合物信息 Entities & Polymers (2)

实体 1 Entity 1 polymer

描述 description	alpha-amino acid ester hydrolase
分子量 formula_weight	72855.4 kDa
EC 编号 ec_number	3.1.1.43
突变 mutation	Y206A
来源方法 src_method	man
拷贝数 entity_count	8

聚合物 Polymer

聚合物类型 type	polypeptide(L)
链编号 strand_id	A,B,C,D,E,F,G,H
原子数 atom_count	39009

APAADAAQAHDPLSVQTGSDIPASVHMPTDQQRDYIKREVMVPMRDGVKLYTVIVIPKNARNAPILLTRTPYNAKGRANRVPNALTMREVLPQGDDVFVEGGYIRVFQDIRGKYGSQGDYVMTRPPHGPLNPTKTDETTDAWDTVDWLVHNVPESNGRVGMTGSSAEGFTVVMALLDPHPALKVAAPESPMVDGWMGDDWFHYGAFRQGAFDYFVSQMTARGGGNDIPRRDADDYTNFLKAGSAGSFATQAGLDQYPFWQRMHAHPAYDAFWQGQALDKILAQRKPTVPMLWEQGLWDQEDMWGAIHAWQALKDADVKAPNTLVMGPWRHSGVNYNGSTLGPLEFEGDTAHQYRRDVFRPFFDEYLKPGSASVHLPDAIIYNTGDQKWDYYRSWPSVCESNCTGGLTPLYLADGHGLSFTHPAADGADSYVSDPAHPVPFISRPFAFAQSSRWKPWLVQDQREAESRPDVVTYETEVLDEPVRVSGVPVADLFAATSGTDSDWVVKLIDVQPAMTPDDPKMGGYELPVSMDIFRGRYRKDFAKPEALQPDATLHYHFTLPAVNHVFAKGHRIMVQIQSSWFPLYDRNPQKFVPNIFDAKPADYTVATQSIHHGGKEATSILLPVVKQKLGPEQKLISEEDLNSAVDHHHHHH

来源 Source

来源生物 organism	Acetobacter pasteurianus
NCBI 分类编号 ncbi_taxonomy_id	438
宿主生物 host_organism	Escherichia coli

实体 2 Entity 2 water

描述 description	water
分子量 formula_weight	18.0 kDa
来源方法 src_method	nat
拷贝数 entity_count	321

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6. 折叠分类 (SCOP + CATH) 40 domains

SCOP 2.08 (16 domains)

结构域编号 domain_id	d1ryya1
类 Class class	b — All beta proteins
折叠类型 Fold fold	b.18 — Galactose-binding domain-like
超家族 Superfamily superfamily	b.18.1 — Galactose-binding domain-like
家族 Family family	b.18.1.13 — PepX C-terminal domain-like

结构域编号 domain_id	d1ryya2
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.69 — alpha/beta-Hydrolases
超家族 Superfamily superfamily	c.69.1 — alpha/beta-Hydrolases
家族 Family family	c.69.1.21 — PepX catalytic domain-like

结构域编号 domain_id	d1ryyb1
类 Class class	b — All beta proteins
折叠类型 Fold fold	b.18 — Galactose-binding domain-like
超家族 Superfamily superfamily	b.18.1 — Galactose-binding domain-like
家族 Family family	b.18.1.13 — PepX C-terminal domain-like

结构域编号 domain_id	d1ryyb2
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.69 — alpha/beta-Hydrolases
超家族 Superfamily superfamily	c.69.1 — alpha/beta-Hydrolases
家族 Family family	c.69.1.21 — PepX catalytic domain-like

结构域编号 domain_id	d1ryyc1
类 Class class	b — All beta proteins
折叠类型 Fold fold	b.18 — Galactose-binding domain-like
超家族 Superfamily superfamily	b.18.1 — Galactose-binding domain-like
家族 Family family	b.18.1.13 — PepX C-terminal domain-like

结构域编号 domain_id	d1ryyc2
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.69 — alpha/beta-Hydrolases
超家族 Superfamily superfamily	c.69.1 — alpha/beta-Hydrolases
家族 Family family	c.69.1.21 — PepX catalytic domain-like

结构域编号 domain_id	d1ryyd1
类 Class class	b — All beta proteins
折叠类型 Fold fold	b.18 — Galactose-binding domain-like
超家族 Superfamily superfamily	b.18.1 — Galactose-binding domain-like
家族 Family family	b.18.1.13 — PepX C-terminal domain-like

结构域编号 domain_id	d1ryyd2
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.69 — alpha/beta-Hydrolases
超家族 Superfamily superfamily	c.69.1 — alpha/beta-Hydrolases
家族 Family family	c.69.1.21 — PepX catalytic domain-like

结构域编号 domain_id	d1ryye1
类 Class class	b — All beta proteins
折叠类型 Fold fold	b.18 — Galactose-binding domain-like
超家族 Superfamily superfamily	b.18.1 — Galactose-binding domain-like
家族 Family family	b.18.1.13 — PepX C-terminal domain-like

结构域编号 domain_id	d1ryye2
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.69 — alpha/beta-Hydrolases
超家族 Superfamily superfamily	c.69.1 — alpha/beta-Hydrolases
家族 Family family	c.69.1.21 — PepX catalytic domain-like

结构域编号 domain_id	d1ryyf1
类 Class class	b — All beta proteins
折叠类型 Fold fold	b.18 — Galactose-binding domain-like
超家族 Superfamily superfamily	b.18.1 — Galactose-binding domain-like
家族 Family family	b.18.1.13 — PepX C-terminal domain-like

结构域编号 domain_id	d1ryyf2
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.69 — alpha/beta-Hydrolases
超家族 Superfamily superfamily	c.69.1 — alpha/beta-Hydrolases
家族 Family family	c.69.1.21 — PepX catalytic domain-like

结构域编号 domain_id	d1ryyg1
类 Class class	b — All beta proteins
折叠类型 Fold fold	b.18 — Galactose-binding domain-like
超家族 Superfamily superfamily	b.18.1 — Galactose-binding domain-like
家族 Family family	b.18.1.13 — PepX C-terminal domain-like

结构域编号 domain_id	d1ryyg2
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.69 — alpha/beta-Hydrolases
超家族 Superfamily superfamily	c.69.1 — alpha/beta-Hydrolases
家族 Family family	c.69.1.21 — PepX catalytic domain-like

结构域编号 domain_id	d1ryyh1
类 Class class	b — All beta proteins
折叠类型 Fold fold	b.18 — Galactose-binding domain-like
超家族 Superfamily superfamily	b.18.1 — Galactose-binding domain-like
家族 Family family	b.18.1.13 — PepX C-terminal domain-like

结构域编号 domain_id	d1ryyh2
类 Class class	c — Alpha and beta proteins (a/b)
折叠类型 Fold fold	c.69 — alpha/beta-Hydrolases
超家族 Superfamily superfamily	c.69.1 — alpha/beta-Hydrolases
家族 Family family	c.69.1.21 — PepX catalytic domain-like

CATH v4.4 (24 domains)

结构域编号 domain_id	1ryyA01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	1820 — Alpha/Beta hydrolase fold, catalytic domain

结构域编号 domain_id	1ryyA02
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	3020 — alpha-amino acid ester hydrolase ( Helical cap domain)
同源超家族 H-superfamily homologous superfamily	10 — alpha-amino acid ester hydrolase ( Helical cap domain)

结构域编号 domain_id	1ryyA03
类 Class class	2 — Mainly Beta
架构 Architecture architecture	60 — Sandwich
拓扑 Topology topology	120 — Jelly Rolls
同源超家族 H-superfamily homologous superfamily	260 — Galactose-binding domain-like

结构域编号 domain_id	1ryyB01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	1820 — Alpha/Beta hydrolase fold, catalytic domain

结构域编号 domain_id	1ryyB02
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	3020 — alpha-amino acid ester hydrolase ( Helical cap domain)
同源超家族 H-superfamily homologous superfamily	10 — alpha-amino acid ester hydrolase ( Helical cap domain)

结构域编号 domain_id	1ryyB03
类 Class class	2 — Mainly Beta
架构 Architecture architecture	60 — Sandwich
拓扑 Topology topology	120 — Jelly Rolls
同源超家族 H-superfamily homologous superfamily	260 — Galactose-binding domain-like

结构域编号 domain_id	1ryyC01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	1820 — Alpha/Beta hydrolase fold, catalytic domain

结构域编号 domain_id	1ryyC02
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	3020 — alpha-amino acid ester hydrolase ( Helical cap domain)
同源超家族 H-superfamily homologous superfamily	10 — alpha-amino acid ester hydrolase ( Helical cap domain)

结构域编号 domain_id	1ryyC03
类 Class class	2 — Mainly Beta
架构 Architecture architecture	60 — Sandwich
拓扑 Topology topology	120 — Jelly Rolls
同源超家族 H-superfamily homologous superfamily	260 — Galactose-binding domain-like

结构域编号 domain_id	1ryyD01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	1820 — Alpha/Beta hydrolase fold, catalytic domain

结构域编号 domain_id	1ryyD02
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	3020 — alpha-amino acid ester hydrolase ( Helical cap domain)
同源超家族 H-superfamily homologous superfamily	10 — alpha-amino acid ester hydrolase ( Helical cap domain)

结构域编号 domain_id	1ryyD03
类 Class class	2 — Mainly Beta
架构 Architecture architecture	60 — Sandwich
拓扑 Topology topology	120 — Jelly Rolls
同源超家族 H-superfamily homologous superfamily	260 — Galactose-binding domain-like

结构域编号 domain_id	1ryyE01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	1820 — Alpha/Beta hydrolase fold, catalytic domain

结构域编号 domain_id	1ryyE02
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	3020 — alpha-amino acid ester hydrolase ( Helical cap domain)
同源超家族 H-superfamily homologous superfamily	10 — alpha-amino acid ester hydrolase ( Helical cap domain)

结构域编号 domain_id	1ryyE03
类 Class class	2 — Mainly Beta
架构 Architecture architecture	60 — Sandwich
拓扑 Topology topology	120 — Jelly Rolls
同源超家族 H-superfamily homologous superfamily	260 — Galactose-binding domain-like

结构域编号 domain_id	1ryyF01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	1820 — Alpha/Beta hydrolase fold, catalytic domain

结构域编号 domain_id	1ryyF02
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	3020 — alpha-amino acid ester hydrolase ( Helical cap domain)
同源超家族 H-superfamily homologous superfamily	10 — alpha-amino acid ester hydrolase ( Helical cap domain)

结构域编号 domain_id	1ryyF03
类 Class class	2 — Mainly Beta
架构 Architecture architecture	60 — Sandwich
拓扑 Topology topology	120 — Jelly Rolls
同源超家族 H-superfamily homologous superfamily	260 — Galactose-binding domain-like

结构域编号 domain_id	1ryyG01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	1820 — Alpha/Beta hydrolase fold, catalytic domain

结构域编号 domain_id	1ryyG02
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	3020 — alpha-amino acid ester hydrolase ( Helical cap domain)
同源超家族 H-superfamily homologous superfamily	10 — alpha-amino acid ester hydrolase ( Helical cap domain)

结构域编号 domain_id	1ryyG03
类 Class class	2 — Mainly Beta
架构 Architecture architecture	60 — Sandwich
拓扑 Topology topology	120 — Jelly Rolls
同源超家族 H-superfamily homologous superfamily	260 — Galactose-binding domain-like

结构域编号 domain_id	1ryyH01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	1820 — Alpha/Beta hydrolase fold, catalytic domain

结构域编号 domain_id	1ryyH02
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	10 — Orthogonal Bundle
拓扑 Topology topology	3020 — alpha-amino acid ester hydrolase ( Helical cap domain)
同源超家族 H-superfamily homologous superfamily	10 — alpha-amino acid ester hydrolase ( Helical cap domain)

结构域编号 domain_id	1ryyH03
类 Class class	2 — Mainly Beta
架构 Architecture architecture	60 — Sandwich
拓扑 Topology topology	120 — Jelly Rolls
同源超家族 H-superfamily homologous superfamily	260 — Galactose-binding domain-like

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晶胞边长 a length_a	91.649 Å
晶胞边长 b length_b	177.513 Å
晶胞边长 c length_c	169.967 Å
晶胞夹角 α angle_alpha	90.00 °
晶胞夹角 β angle_beta	91.03 °
晶胞夹角 γ angle_gamma	90.00 °
晶胞分子数 Z z_pdb	16

空间群 space_group	P 1 21 1
空间群编号 int_tables_number	4
晶系 crystal_system	—

分辨率 resolution	2.800 Å
最低分辨率 resolution_low	15.000 Å
R 因子 r_factor	0.2110
R_work r_work	0.2097
R_free r_free	0.2359

Acetobacter turbidans alpha-amino acid ester hydrolase Y206A mutant

1. 蛋白身份与相关结构 Protein Identity & Related Structures

alpha-amino acid ester hydrolase

当前结构中的状态

数据库中的同蛋白其他状态

2. 结构基本信息 2. Structure Basics

3. Official assembly/model 理论 SAXS Official SAXS Profiles

1ryy__assembly_1__model_1

1ryy__assembly_1__model_1 | I(q)

1ryy__assembly_1__model_1 | P(r) · Pending

4. 晶体学与实验 4. Crystallography & Experiment

晶胞参数 Unit Cell

对称性 Symmetry

精修参数 Refinement

衍射实验 Diffraction

5. 实体与聚合物信息 Entities & Polymers (2)

实体 1 Entity 1 polymer

聚合物 Polymer

来源 Source

实体 2 Entity 2 water

6. 折叠分类 (SCOP + CATH) 40 domains

SCOP 2.08 (16 domains)

CATH v4.4 (24 domains)

7. 引用文献 (1)

Acetobacter turbidans alpha-amino acid ester hydrolase Y206A mutant

1. 蛋白身份与相关结构 Protein Identity & Related Structures

alpha-amino acid ester hydrolase

当前结构中的状态

数据库中的同蛋白其他状态

单体

同源二聚体

同源四聚体

其他同源多聚体

异源或核酸复合物

2. 结构基本信息 2. Structure Basics

3. Official assembly/model 理论 SAXS Official SAXS Profiles

1ryy__assembly_1__model_1

1ryy__assembly_1__model_1 | I(q)

1ryy__assembly_1__model_1 | P(r) · Pending

4. 晶体学与实验 4. Crystallography & Experiment

晶胞参数 Unit Cell

对称性 Symmetry

精修参数 Refinement

衍射实验 Diffraction

5. 实体与聚合物信息 Entities & Polymers (2)

实体 1 Entity 1 polymer

聚合物 Polymer

来源 Source

实体 2 Entity 2 water

6. 折叠分类 (SCOP + CATH) 40 domains

SCOP 2.08 (16 domains)

CATH v4.4 (24 domains)

7. 引用文献 (1)