Homo sapiens
| Assembly | 物理组成 | 蛋白状态 | 分子拷贝数 | 共同组分 | 数据核对 |
|---|---|---|---|---|---|
| 1 | 蛋白异源复合物 | 异源复合物 | 蛋白 4 | Rho-associated, coiled-coil containing protein kinase 1 × 2 （Q13464） MAGNESIUM ION × 2 PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER × 2 water × 4 | 与蛋白数一致 |
| UniProt名称 | RHOA_HUMAN |
| Isoform | — |
| PDB实体 | 1 |
| 链与序列区间 | 作者链 A； PDB构建体 3–183； UniProt 1–181 作者链 B； PDB构建体 3–183； UniProt 1–181 |
Homo sapiens
| Assembly | 物理组成 | 蛋白状态 | 分子拷贝数 | 共同组分 | 数据核对 |
|---|---|---|---|---|---|
| 1 | 蛋白异源复合物 | 异源复合物 | 蛋白 4 | Transforming protein RhoA × 2 （P61586） MAGNESIUM ION × 2 PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER × 2 water × 4 | 与蛋白数一致 |
| UniProt名称 | ROCK1_HUMAN |
| Isoform | — |
| PDB实体 | 2 |
| 链与序列区间 | 作者链 X； PDB构建体 3–71； UniProt 946–1015 作者链 Y； PDB构建体 3–71； UniProt 946–1015 |
页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。
| 条目编号 entry_id | 1s1c |
| 沉积日期 deposition_date | 2004-01-06 |
| 结构标题 title | Crystal structure of the complex between the human RhoA and Rho-binding domain of human ROCKI |
| 关键词 keywords | coiled-coil, GTPase, Rho kinase, ROCK, SIGNALING PROTEIN; SIGNALING PROTEIN |
| 实验方法 method | X-RAY DIFFRACTION |
页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 33.53 Å |
| Rg（电子密度） | 33.61 Å |
| 总 Rg | 34.01 Å |
| 原子数 | 4017 |
| 残基数 | 497 |
| 排除体积 | 71369 ų |
| 最大 q | 0.500 Å⁻¹ |
| 结构域编号 domain_id | d1s1ca_ |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.37 — P-loop containing nucleoside triphosphate hydrolases |
| 超家族 Superfamily superfamily | c.37.1 — P-loop containing nucleoside triphosphate hydrolases |
| 家族 Family family | c.37.1.8 — G proteins |
| 结构域编号 domain_id | d1s1cb_ |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.37 — P-loop containing nucleoside triphosphate hydrolases |
| 超家族 Superfamily superfamily | c.37.1 — P-loop containing nucleoside triphosphate hydrolases |
| 家族 Family family | c.37.1.8 — G proteins |
| 结构域编号 domain_id | d1s1cx1 |
| 类 Class class | h — Coiled coil proteins |
| 折叠类型 Fold fold | h.1 — Parallel coiled-coil |
| 超家族 Superfamily superfamily | h.1.27 — G protein-binding domain |
| 家族 Family family | h.1.27.1 — RhoA-binding domain |
| 结构域编号 domain_id | d1s1cx2 |
| 类 Class class | l — Artifacts |
| 折叠类型 Fold fold | l.1 — Tags |
| 超家族 Superfamily superfamily | l.1.1 — Tags |
| 家族 Family family | l.1.1.1 — Tags |
| 结构域编号 domain_id | d1s1cy1 |
| 类 Class class | h — Coiled coil proteins |
| 折叠类型 Fold fold | h.1 — Parallel coiled-coil |
| 超家族 Superfamily superfamily | h.1.27 — G protein-binding domain |
| 家族 Family family | h.1.27.1 — RhoA-binding domain |
| 结构域编号 domain_id | d1s1cy2 |
| 类 Class class | l — Artifacts |
| 折叠类型 Fold fold | l.1 — Tags |
| 超家族 Superfamily superfamily | l.1.1 — Tags |
| 家族 Family family | l.1.1.1 — Tags |
| 结构域编号 domain_id | 1s1cA00 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 300 — P-loop containing nucleotide triphosphate hydrolases |
| 结构域编号 domain_id | 1s1cB00 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 300 — P-loop containing nucleotide triphosphate hydrolases |
| 结构域编号 domain_id | 1s1cX00 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 20 — Up-down Bundle |
| 拓扑 Topology topology | 5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces |
| 同源超家族 H-superfamily homologous superfamily | 730 — Single helix bin |
| 结构域编号 domain_id | 1s1cY00 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 20 — Up-down Bundle |
| 拓扑 Topology topology | 5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces |
| 同源超家族 H-superfamily homologous superfamily | 730 — Single helix bin |