1skz

PROTEASE INHIBITOR

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

ANTISTASIN

Haementeria officinalis

UniProt P15358

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 2 CHLORIDE ION × 2 water × 2 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name ANTA_HAEOF
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 1–119; UniProt 1–119

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id1skz
Deposition date deposition_date1997-04-16
Structure title titlePROTEASE INHIBITOR
Keywords keywordsANTISTASIN, FACTOR XA INHIBITOR, SERINE PROTEASE INHIBITOR, THROMBOSIS; SERINE PROTEASE INHIBITOR
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

1skz__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

1skz__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

1skz__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)20.07 Å
Rg (electron density)19.43 Å
Total Rg20.19 Å
Atom count1580
Residues208
Excluded volume27659 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 1skz__assembly_1__model_1 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

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6. Fold Classification (SCOP + CATH) 4 domains

SCOP 2.08 (2 domains)

Domain ID domain_idd1skza1
Class classg — Small proteins
Fold Fold foldg.3 — Knottins (small inhibitors, toxins, lectins)
Superfamily Superfamily superfamilyg.3.15 — Leech antihemostatic proteins
Family Family familyg.3.15.1 — Huristasin-like
Domain ID domain_idd1skza2
Class classg — Small proteins
Fold Fold foldg.3 — Knottins (small inhibitors, toxins, lectins)
Superfamily Superfamily superfamilyg.3.15 — Leech antihemostatic proteins
Family Family familyg.3.15.1 — Huristasin-like

CATH v4.4 (2 domains)

Domain ID domain_id1skzA01
Class class2 — Mainly Beta
Architecture architecture10 — Ribbon
Topology topology22 — Antistasin; domain 1
Homologous superfamily homologous superfamily10 — Antistasin; domain 1
Domain ID domain_id1skzA02
Class class2 — Mainly Beta
Architecture architecture10 — Ribbon
Topology topology22 — Antistasin; domain 1
Homologous superfamily homologous superfamily10 — Antistasin; domain 1
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7. Citations (3)