SAXSdb — 1t10

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1. Protein Identity and Related Structures Protein Identity & Related Structures

Glucose-6-phosphate isomerase

Leishmania mexicana mexicana

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein homooligomer	Homooligomer	Protein 2	6-O-phosphono-beta-D-fructofuranose × 2 water × 2	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	G6PI_LEIME
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain A； PDBConstruct 1–605； UniProt 1–605

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	1t10
Deposition date deposition_date	2004-04-14
Structure title title	Phosphoglucose isomerase from Leishmania mexicana in complex with substrate D-fructose-6-phosphate
Keywords keywords	phosphoglucose isomerase; substrate; D-fructose-6-phosphate, ISOMERASE; ISOMERASE
Experimental Method method	X-RAY DIFFRACTION

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

1t10__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

1t10__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

1t10__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	30.50 Å
Rg (electron density)	29.11 Å
Total Rg	29.99 Å
Atom count	8742
Residues	1112
Excluded volume	154940 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`1t10__assembly_1__model_1`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

Entity 1 Entity 1 polymer

Description description	Glucose-6-phosphate isomerase
Molecular weight formula_weight	67362.2 kDa
EC 编号 ec_number	5.3.1.9
Source method src_method	man
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	A
Atom count atom_count	4551

MSDYFSKLKEHVVESTEINGCTPSIATATFNAPYEVARKTKMLGVTDSSLLNLPAWKRLQSLYEKYGNDSILSHFEKDHQRFQRYSIEIDLHSDDNFLFLDYSKSHINDEIKDALVALAEERGVRAFAKAMFDGQRVNSTENRAVLHVALRNRSNRPIIVDGKDVMSDVNNVLAQMKDFTERVRSGEWKGQTGKSIYNIVNIGIGGSDLGPVMVTEALKPFSKRDLHCFFVSNVDGTHMAEVLKQVNLEETIFIIASKTFTTQETLTNAMSARNALMSYLKENGISTDGAVAKHFVALSTNTEKVREFGIDTVNMFAFWDWVGGRYSVWSAIGLSVMLSIGYDNFVEFLTGAHVMDNHFASTPTEQNLPMMLALVGIWYNNFFGSETQAVLPYDQYLWRLPAYLQQLDMESNGKGVTKKSGAVAVQTGPIVFGEAGTNGQHAFYQLIHQGTKIIPCDFIGCVQTQNRVGDHHRTLMSNFFAQTEALMVGKNAEEVRQELVKSGMSGDAIENMIPHKTFTGSRPSNSILVNALTPRALGAIIAMYEHKVLVQGAIWGINSYDQWGVELGKVLAKSILPQLKSGNIVSDHDGSTNGLINMFNTRAHL

Source Source

Source organism organism	Leishmania mexicana mexicana
NCBI taxonomy ID ncbi_taxonomy_id	44270
Host organism host_organism	Escherichia coli

Entity 2 Entity 2 non-polymer

Description description	6-O-phosphono-beta-D-fructofuranose
Molecular weight formula_weight	260.1 kDa
Source method src_method	man
Copy count entity_count	1

Entity 3 Entity 3 water

Description description	water
Molecular weight formula_weight	18.0 kDa
Source method src_method	nat
Copy count entity_count	180

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6. Fold Classification (SCOP + CATH) 4 domains

SCOP 2.08 (1 domains)

Domain ID domain_id	d1t10a_
Class class	c — Alpha and beta proteins (a/b)
Fold Fold fold	c.80 — SIS domain
Superfamily Superfamily superfamily	c.80.1 — SIS domain
Family Family family	c.80.1.2 — Phosphoglucose isomerase, PGI

CATH v4.4 (3 domains)

Domain ID domain_id	1t10A01
Class class	3 — Alpha Beta
Architecture architecture	40 — 3-Layer(aba) Sandwich
Topology topology	50 — Rossmann fold
Homologous superfamily homologous superfamily	10490 — Glucose-6-phosphate isomerase like protein; domain 1

Domain ID domain_id	1t10A02
Class class	3 — Alpha Beta
Architecture architecture	40 — 3-Layer(aba) Sandwich
Topology topology	50 — Rossmann fold
Homologous superfamily homologous superfamily	10490 — Glucose-6-phosphate isomerase like protein; domain 1

Domain ID domain_id	1t10A03
Class class	1 — Mainly Alpha
Architecture architecture	10 — Orthogonal Bundle
Topology topology	1390 — Phosphoglucose isomerase, C-terminal domain
Homologous superfamily homologous superfamily	10 —

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Unit-cell length a length_a	85.129 Å
Unit-cell length b length_b	85.129 Å
Unit-cell length c length_c	350.089 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	120.00 °
Molecules per unit cell Z z_pdb	12

Space group space_group	P 61 2 2
Space-group number int_tables_number	178
Crystal system crystal_system	—

Resolution resolution	2.350 Å
Low-resolution limit resolution_low	74.530 Å
R factor r_factor	0.2223
R_work r_work	0.2203
R_free r_free	0.2598

Phosphoglucose isomerase from Leishmania mexicana in complex with substrate D-fructose-6-phosphate

1. Protein Identity and Related Structures Protein Identity & Related Structures

Glucose-6-phosphate isomerase

State in the Current Structure

Other States of the Same Protein in the Database

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

1t10__assembly_1__model_1

1t10__assembly_1__model_1 | I(q)

1t10__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

5. Entities and Polymers Entities & Polymers (3)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 non-polymer

Entity 3 Entity 3 water

6. Fold Classification (SCOP + CATH) 4 domains

SCOP 2.08 (1 domains)

CATH v4.4 (3 domains)

7. Citations (1)

Phosphoglucose isomerase from Leishmania mexicana in complex with substrate D-fructose-6-phosphate

1. Protein Identity and Related Structures Protein Identity & Related Structures

Glucose-6-phosphate isomerase

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

1t10__assembly_1__model_1

1t10__assembly_1__model_1 | I(q)

1t10__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

5. Entities and Polymers Entities & Polymers (3)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 non-polymer

Entity 3 Entity 3 water

6. Fold Classification (SCOP + CATH) 4 domains

SCOP 2.08 (1 domains)

CATH v4.4 (3 domains)

7. Citations (1)