Homo sapiens
| Assembly | Physical composition | Protein state | Molecular copy count | Associated components | Data consistency |
|---|---|---|---|---|---|
| 1 | Protein monomer | Monomer | Protein 1 | water × 1 | Consistent with protein count |
| UniProt name | IL1B_HUMAN |
| Isoform | — |
| PDB entities | 1 |
| Chains and sequence ranges | Author chain A； PDBConstruct 1–153； UniProt 117–269 |
The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.
| Entry ID entry_id | 1tp0 |
| Deposition date deposition_date | 2004-06-15 |
| Structure title title | Triple mutation in interleukin 1 beta cavity:replacement of phenylalanines with tryptophan. |
| Keywords keywords | hydrophobic cavity, hydrophobicity, IMMUNE SYSTEM; IMMUNE SYSTEM |
| Experimental Method method | X-RAY DIFFRACTION |
This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 16.31 Å |
| Rg (electron density) | 14.82 Å |
| Total Rg | 16.03 Å |
| Atom count | 1228 |
| Residues | 153 |
| Excluded volume | 21933 ų |
| Maximum q | 0.500 Å⁻¹ |
| Domain ID domain_id | d1tp0a_ |
| Class class | b — All beta proteins |
| Fold Fold fold | b.42 — beta-Trefoil |
| Superfamily Superfamily superfamily | b.42.1 — Cytokine |
| Family Family family | b.42.1.2 — Interleukin-1 (IL-1) |
| Domain ID domain_id | 1tp0A00 |
| Class class | 2 — Mainly Beta |
| Architecture architecture | 80 — Trefoil |
| Topology topology | 10 — Trefoil (Acidic Fibroblast Growth Factor, subunit A) |
| Homologous superfamily homologous superfamily | 50 — |