1u00

HscA substrate binding domain complexed with the IscU recognition peptide ELPPVKIHC

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Chaperone protein hscA

Escherichia coli

UniProt P0A6Z1

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 2 IscU recognition peptide × 1 water × 2 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name HSCA_ECOLI
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 1–227; UniProt 389–615

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id1u00
Deposition date deposition_date2004-07-12
Structure title titleHscA substrate binding domain complexed with the IscU recognition peptide ELPPVKIHC
Keywords keywordsHscA, Hsc66, DnaK, Hsp70, IscU, CHAPERONE; CHAPERONE
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

1u00__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

1u00__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

1u00__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)22.53 Å
Rg (electron density)21.80 Å
Total Rg22.52 Å
Atom count1738
Residues236
Excluded volume30739 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 1u00__assembly_1__model_1 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

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6. Fold Classification (SCOP + CATH) 4 domains

SCOP 2.08 (2 domains)

Domain ID domain_idd1u00a1
Class classa — All alpha proteins
Fold Fold folda.8 — immunoglobulin/albumin-binding domain-like
Superfamily Superfamily superfamilya.8.4 — Heat shock protein 70kD (HSP70), C-terminal subdomain
Family Family familya.8.4.1 — Heat shock protein 70kD (HSP70), C-terminal subdomain
Domain ID domain_idd1u00a2
Class classb — All beta proteins
Fold Fold foldb.130 — Heat shock protein 70kD (HSP70), peptide-binding domain
Superfamily Superfamily superfamilyb.130.1 — Heat shock protein 70kD (HSP70), peptide-binding domain
Family Family familyb.130.1.1 — Heat shock protein 70kD (HSP70), peptide-binding domain

CATH v4.4 (2 domains)

Domain ID domain_id1u00A01
Class class2 — Mainly Beta
Architecture architecture60 — Sandwich
Topology topology34 — Substrate Binding Domain Of DNAk; Chain A, domain 1
Homologous superfamily homologous superfamily10 — Substrate Binding Domain Of DNAk; Chain A, domain 1
Domain ID domain_id1u00A02
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology1270 — Substrate Binding Domain Of Dnak; Chain:A; Domain 2
Homologous superfamily homologous superfamily10 —
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7. Citations (1)