1ukl

Crystal structure of Importin-beta and SREBP-2 complex

Method: X-RAY DIFFRACTION Dmax: 142.0 Å Quality: GOOD

SAXS 散射曲线 SAXS Profile

SAXS profile for 1ukl

P(r) 距离分布 P(r) Distribution

P(r) distribution for 1ukl
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1. 结构基本信息 1. Structure Basics

条目编号 entry_id1ukl
沉积日期 deposition_date2003-08-26
结构标题 titleCrystal structure of Importin-beta and SREBP-2 complex
关键词 keywords;Transcription factor, Nuclear transport factor, HEAT repeat, Helix-Loop-Helix Leucine zipper, PROTEIN TRANSPORT-DNA BINDING PROTEIN COMPLEX ;; PROTEIN TRANSPORT/DNA BINDING PROTEIN
实验方法 methodX-RAY DIFFRACTION

2. SAXS 参数 (CRYSOL 理论计算) 2. SAXS Parameters (CRYSOL)

回转半径 Rg (Guinier) rg_guinier43.37
回转半径 Rg (电子) rg_electron43.03
零角强度 I(0) i0745647000.00
分子量 molecular_weight223360.0 kDa
排除体积 excluded_volume279400 ų
包络体积 envelope_volume403370 ų
水化壳体积 shell_volume77350 ų
包络直径 envelope_diameter151.8
壳层 Rg shell_rg48.76
包络 Rg envelope_rg42.22
形状 Rg shape_rg43.07
总 Rg total_rg43.17
总原子数 total_atoms15606
残基数 n_residues1984
球谐函数阶数 n_harmonics20
q 范围 q_range— – 0.5000 −1
数据点数 n_points101
壳层类型 shell_typedirectional
溶剂电子密度 solvent_density0.3340 e/ų
壳层衬度 contrast_shell0.0300 e/ų
CRYSOL 版本 crysol_version4.1.3

3. P(r) 距离分布 (GNOM 反演) 3. P(r) Analysis (GNOM)

最大尺寸 Dmax dmax142.0
Rg (实空间) rg_real43.24
Rg 误差 (实空间) rg_real_error0.91
I(0) (实空间) i0_real7.4560e+08
I(0) 误差 (实空间) i0_real_error1.1760e+07
Rg (倒空间) rg_reciprocal43.37
I(0) (倒空间) i0_reciprocal745800000.0000
解质量估计 total_estimate0.8712
解质量评级 solution_quality GOOD a GOOD solution
P(r) 峰数 n_peaks1
主峰位置 r_peak_primary55.2
偏度 Skewness skewness0.272
峰度 Kurtosis kurtosis-0.227
角度范围 angular_range— – 0.1800 −1
当前正则化参数 α current_alpha0.0001
最高正则化参数 α highest_alpha64630000.0000
实空间数据点数 n_real_points37
GNOM 版本 gnom_version4.1.3
质量判据 quality_criteria AN1: 0.000; Oscil: 0.826; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.989; Smooth: 0.852

4. 晶体学与实验 4. Crystallography & Experiment

5. 实体与聚合体信息 (2)

6. 折叠分类 (SCOP + CATH) 12 domains

SCOP 2.08 (6 domains)

结构域编号 domain_idd1ukla_
类 Class classa — All alpha proteins
折叠类型 Fold folda.118 — alpha-alpha superhelix
超家族 Superfamily superfamilya.118.1 — ARM repeat
家族 Family familya.118.1.1 — Armadillo repeat
结构域编号 domain_idd1uklb_
类 Class classa — All alpha proteins
折叠类型 Fold folda.118 — alpha-alpha superhelix
超家族 Superfamily superfamilya.118.1 — ARM repeat
家族 Family familya.118.1.1 — Armadillo repeat
结构域编号 domain_idd1uklc_
类 Class classa — All alpha proteins
折叠类型 Fold folda.38 — HLH-like
超家族 Superfamily superfamilya.38.1 — HLH, helix-loop-helix DNA-binding domain
家族 Family familya.38.1.1 — HLH, helix-loop-helix DNA-binding domain
结构域编号 domain_idd1ukld_
类 Class classa — All alpha proteins
折叠类型 Fold folda.38 — HLH-like
超家族 Superfamily superfamilya.38.1 — HLH, helix-loop-helix DNA-binding domain
家族 Family familya.38.1.1 — HLH, helix-loop-helix DNA-binding domain
结构域编号 domain_idd1ukle_
类 Class classa — All alpha proteins
折叠类型 Fold folda.38 — HLH-like
超家族 Superfamily superfamilya.38.1 — HLH, helix-loop-helix DNA-binding domain
家族 Family familya.38.1.1 — HLH, helix-loop-helix DNA-binding domain
结构域编号 domain_idd1uklf_
类 Class classa — All alpha proteins
折叠类型 Fold folda.38 — HLH-like
超家族 Superfamily superfamilya.38.1 — HLH, helix-loop-helix DNA-binding domain
家族 Family familya.38.1.1 — HLH, helix-loop-helix DNA-binding domain

CATH v4.4 (6 domains)

结构域编号 domain_id1uklA00
类 Class class1 — Mainly Alpha
架构 Architecture architecture25 — Alpha Horseshoe
拓扑 Topology topology10 — Leucine-rich Repeat Variant
同源超家族 H-superfamily homologous superfamily10 — Leucine-rich Repeat Variant
结构域编号 domain_id1uklB00
类 Class class1 — Mainly Alpha
架构 Architecture architecture25 — Alpha Horseshoe
拓扑 Topology topology10 — Leucine-rich Repeat Variant
同源超家族 H-superfamily homologous superfamily10 — Leucine-rich Repeat Variant
结构域编号 domain_id1uklC00
类 Class class4 — Few Secondary Structures
架构 Architecture architecture10 — Irregular
拓扑 Topology topology280 — MYOD Basic-Helix-Loop-Helix Domain, subunit B
同源超家族 H-superfamily homologous superfamily10 — Helix-loop-helix DNA-binding domain
结构域编号 domain_id1uklD00
类 Class class4 — Few Secondary Structures
架构 Architecture architecture10 — Irregular
拓扑 Topology topology280 — MYOD Basic-Helix-Loop-Helix Domain, subunit B
同源超家族 H-superfamily homologous superfamily10 — Helix-loop-helix DNA-binding domain
结构域编号 domain_id1uklE00
类 Class class4 — Few Secondary Structures
架构 Architecture architecture10 — Irregular
拓扑 Topology topology280 — MYOD Basic-Helix-Loop-Helix Domain, subunit B
同源超家族 H-superfamily homologous superfamily10 — Helix-loop-helix DNA-binding domain
结构域编号 domain_id1uklF00
类 Class class4 — Few Secondary Structures
架构 Architecture architecture10 — Irregular
拓扑 Topology topology280 — MYOD Basic-Helix-Loop-Helix Domain, subunit B
同源超家族 H-superfamily homologous superfamily10 — Helix-loop-helix DNA-binding domain

7. 引用文献 (1)

8. 文件与曲线 (10)