1vyh
PAF-AH Holoenzyme: Lis1/Alfa2
SAXS 散射曲线 SAXS Profile
P(r) 距离分布 P(r) Distribution
1. 结构基本信息 1. Structure Basics
| 条目编号 entry_id | 1vyh |
| 沉积日期 deposition_date | 2004-04-30 |
| 结构标题 title | PAF-AH Holoenzyme: Lis1/Alfa2 |
| 关键词 keywords | ;LISSENCEPHALY, ACETYLHYDROLASE, PLATELET ACTIVACTING FACTOR, REGULATOR OF CYTOPLASMIC DYNEIN, HYDROLASE, CELL DIVISION, MITOSIS, NEUROGENESIS, CYTOSKELETON ;; HYDROLASE |
| 实验方法 method | X-RAY DIFFRACTION |
2. SAXS 参数 (CRYSOL 理论计算) 2. SAXS Parameters (CRYSOL)
| 回转半径 Rg (Guinier) rg_guinier | 81.39 Å |
| 回转半径 Rg (电子) rg_electron | 81.97 Å |
| 零角强度 I(0) i0 | 4989300000.00 |
| 分子量 molecular_weight | 591470.0 kDa |
| 排除体积 excluded_volume | 737140 ų |
| 包络体积 envelope_volume | 1208600 ų |
| 水化壳体积 shell_volume | 132570 ų |
| 包络直径 envelope_diameter | 302.6 Å |
| 壳层 Rg shell_rg | 69.00 Å |
| 包络 Rg envelope_rg | 79.10 Å |
| 形状 Rg shape_rg | 81.96 Å |
| 总 Rg total_rg | 81.84 Å |
| 总原子数 total_atoms | 41590 |
| 残基数 n_residues | 5280 |
| 球谐函数阶数 n_harmonics | 20 |
| q 范围 q_range | — – 0.5000 Å−1 |
| 数据点数 n_points | 101 |
| 壳层类型 shell_type | directional |
| 溶剂电子密度 solvent_density | 0.3340 e/ų |
| 壳层衬度 contrast_shell | 0.0300 e/ų |
| CRYSOL 版本 crysol_version | 4.1.3 |
3. P(r) 距离分布 (GNOM 反演) 3. P(r) Analysis (GNOM)
| 最大尺寸 Dmax dmax | 234.7 Å |
| Rg (实空间) rg_real | 79.59 Å |
| Rg 误差 (实空间) rg_real_error | 1.06 Å |
| I(0) (实空间) i0_real | 4.8810e+09 |
| I(0) 误差 (实空间) i0_real_error | 9.9280e+07 |
| Rg (倒空间) rg_reciprocal | 79.63 Å |
| I(0) (倒空间) i0_reciprocal | 4965000000.0000 |
| 解质量估计 total_estimate | 0.8674 |
| 解质量评级 solution_quality | GOOD a GOOD solution |
| P(r) 峰数 n_peaks | 1 |
| 主峰位置 r_peak_primary | 86.5 Å |
| 偏度 Skewness skewness | 0.242 |
| 峰度 Kurtosis kurtosis | -0.654 |
| 角度范围 angular_range | — – 0.0950 Å−1 |
| 当前正则化参数 α current_alpha | 0.8189 |
| 最高正则化参数 α highest_alpha | 114800000.0000 |
| 实空间数据点数 n_real_points | 20 |
| GNOM 版本 gnom_version | 4.1.3 |
| 质量判据 quality_criteria | AN1: 0.000; Oscil: 1.000; Stabil: 0.984; Sysdev: 1.000; Positv: 1.000; Valcen: 1.000; Smooth: 0.001 |
4. 晶体学与实验 4. Crystallography & Experiment
5. 实体与聚合体信息 (2)
6. 折叠分类 (SCOP + CATH) 40 domains
SCOP 2.08 (20 domains)
| 结构域编号 domain_id | d1vyha1 |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.23 — Flavodoxin-like |
| 超家族 Superfamily superfamily | c.23.10 — SGNH hydrolase |
| 家族 Family family | c.23.10.3 — Acetylhydrolase |
| 结构域编号 domain_id | d1vyhb1 |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.23 — Flavodoxin-like |
| 超家族 Superfamily superfamily | c.23.10 — SGNH hydrolase |
| 家族 Family family | c.23.10.3 — Acetylhydrolase |
| 结构域编号 domain_id | d1vyhc1 |
| 类 Class class | b — All beta proteins |
| 折叠类型 Fold fold | b.69 — 7-bladed beta-propeller |
| 超家族 Superfamily superfamily | b.69.4 — WD40 repeat-like |
| 家族 Family family | b.69.4.1 — WD40-repeat |
| 结构域编号 domain_id | d1vyhd1 |
| 类 Class class | b — All beta proteins |
| 折叠类型 Fold fold | b.69 — 7-bladed beta-propeller |
| 超家族 Superfamily superfamily | b.69.4 — WD40 repeat-like |
| 家族 Family family | b.69.4.1 — WD40-repeat |
| 结构域编号 domain_id | d1vyhe1 |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.23 — Flavodoxin-like |
| 超家族 Superfamily superfamily | c.23.10 — SGNH hydrolase |
| 家族 Family family | c.23.10.3 — Acetylhydrolase |
| 结构域编号 domain_id | d1vyhf1 |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.23 — Flavodoxin-like |
| 超家族 Superfamily superfamily | c.23.10 — SGNH hydrolase |
| 家族 Family family | c.23.10.3 — Acetylhydrolase |
| 结构域编号 domain_id | d1vyhg1 |
| 类 Class class | b — All beta proteins |
| 折叠类型 Fold fold | b.69 — 7-bladed beta-propeller |
| 超家族 Superfamily superfamily | b.69.4 — WD40 repeat-like |
| 家族 Family family | b.69.4.1 — WD40-repeat |
| 结构域编号 domain_id | d1vyhh1 |
| 类 Class class | b — All beta proteins |
| 折叠类型 Fold fold | b.69 — 7-bladed beta-propeller |
| 超家族 Superfamily superfamily | b.69.4 — WD40 repeat-like |
| 家族 Family family | b.69.4.1 — WD40-repeat |
| 结构域编号 domain_id | d1vyhi1 |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.23 — Flavodoxin-like |
| 超家族 Superfamily superfamily | c.23.10 — SGNH hydrolase |
| 家族 Family family | c.23.10.3 — Acetylhydrolase |
| 结构域编号 domain_id | d1vyhj1 |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.23 — Flavodoxin-like |
| 超家族 Superfamily superfamily | c.23.10 — SGNH hydrolase |
| 家族 Family family | c.23.10.3 — Acetylhydrolase |
| 结构域编号 domain_id | d1vyhk1 |
| 类 Class class | b — All beta proteins |
| 折叠类型 Fold fold | b.69 — 7-bladed beta-propeller |
| 超家族 Superfamily superfamily | b.69.4 — WD40 repeat-like |
| 家族 Family family | b.69.4.1 — WD40-repeat |
| 结构域编号 domain_id | d1vyhl1 |
| 类 Class class | b — All beta proteins |
| 折叠类型 Fold fold | b.69 — 7-bladed beta-propeller |
| 超家族 Superfamily superfamily | b.69.4 — WD40 repeat-like |
| 家族 Family family | b.69.4.1 — WD40-repeat |
| 结构域编号 domain_id | d1vyhm1 |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.23 — Flavodoxin-like |
| 超家族 Superfamily superfamily | c.23.10 — SGNH hydrolase |
| 家族 Family family | c.23.10.3 — Acetylhydrolase |
| 结构域编号 domain_id | d1vyhn1 |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.23 — Flavodoxin-like |
| 超家族 Superfamily superfamily | c.23.10 — SGNH hydrolase |
| 家族 Family family | c.23.10.3 — Acetylhydrolase |
| 结构域编号 domain_id | d1vyho1 |
| 类 Class class | b — All beta proteins |
| 折叠类型 Fold fold | b.69 — 7-bladed beta-propeller |
| 超家族 Superfamily superfamily | b.69.4 — WD40 repeat-like |
| 家族 Family family | b.69.4.1 — WD40-repeat |
| 结构域编号 domain_id | d1vyhp1 |
| 类 Class class | b — All beta proteins |
| 折叠类型 Fold fold | b.69 — 7-bladed beta-propeller |
| 超家族 Superfamily superfamily | b.69.4 — WD40 repeat-like |
| 家族 Family family | b.69.4.1 — WD40-repeat |
| 结构域编号 domain_id | d1vyhq1 |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.23 — Flavodoxin-like |
| 超家族 Superfamily superfamily | c.23.10 — SGNH hydrolase |
| 家族 Family family | c.23.10.3 — Acetylhydrolase |
| 结构域编号 domain_id | d1vyhr1 |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.23 — Flavodoxin-like |
| 超家族 Superfamily superfamily | c.23.10 — SGNH hydrolase |
| 家族 Family family | c.23.10.3 — Acetylhydrolase |
| 结构域编号 domain_id | d1vyhs1 |
| 类 Class class | b — All beta proteins |
| 折叠类型 Fold fold | b.69 — 7-bladed beta-propeller |
| 超家族 Superfamily superfamily | b.69.4 — WD40 repeat-like |
| 家族 Family family | b.69.4.1 — WD40-repeat |
| 结构域编号 domain_id | d1vyht1 |
| 类 Class class | b — All beta proteins |
| 折叠类型 Fold fold | b.69 — 7-bladed beta-propeller |
| 超家族 Superfamily superfamily | b.69.4 — WD40 repeat-like |
| 家族 Family family | b.69.4.1 — WD40-repeat |
CATH v4.4 (20 domains)
| 结构域编号 domain_id | 1vyhA00 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 1110 — SGNH hydrolase |
| 结构域编号 domain_id | 1vyhB00 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 1110 — SGNH hydrolase |
| 结构域编号 domain_id | 1vyhC01 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 130 — 7 Propeller |
| 拓扑 Topology topology | 10 — Methylamine Dehydrogenase; Chain H |
| 同源超家族 H-superfamily homologous superfamily | 10 — YVTN repeat-like/Quinoprotein amine dehydrogenase |
| 结构域编号 domain_id | 1vyhD01 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 130 — 7 Propeller |
| 拓扑 Topology topology | 10 — Methylamine Dehydrogenase; Chain H |
| 同源超家族 H-superfamily homologous superfamily | 10 — YVTN repeat-like/Quinoprotein amine dehydrogenase |
| 结构域编号 domain_id | 1vyhE00 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 1110 — SGNH hydrolase |
| 结构域编号 domain_id | 1vyhF00 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 1110 — SGNH hydrolase |
| 结构域编号 domain_id | 1vyhG01 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 130 — 7 Propeller |
| 拓扑 Topology topology | 10 — Methylamine Dehydrogenase; Chain H |
| 同源超家族 H-superfamily homologous superfamily | 10 — YVTN repeat-like/Quinoprotein amine dehydrogenase |
| 结构域编号 domain_id | 1vyhH01 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 130 — 7 Propeller |
| 拓扑 Topology topology | 10 — Methylamine Dehydrogenase; Chain H |
| 同源超家族 H-superfamily homologous superfamily | 10 — YVTN repeat-like/Quinoprotein amine dehydrogenase |
| 结构域编号 domain_id | 1vyhI00 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 1110 — SGNH hydrolase |
| 结构域编号 domain_id | 1vyhJ00 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 1110 — SGNH hydrolase |
| 结构域编号 domain_id | 1vyhK01 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 130 — 7 Propeller |
| 拓扑 Topology topology | 10 — Methylamine Dehydrogenase; Chain H |
| 同源超家族 H-superfamily homologous superfamily | 10 — YVTN repeat-like/Quinoprotein amine dehydrogenase |
| 结构域编号 domain_id | 1vyhL01 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 130 — 7 Propeller |
| 拓扑 Topology topology | 10 — Methylamine Dehydrogenase; Chain H |
| 同源超家族 H-superfamily homologous superfamily | 10 — YVTN repeat-like/Quinoprotein amine dehydrogenase |
| 结构域编号 domain_id | 1vyhM00 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 1110 — SGNH hydrolase |
| 结构域编号 domain_id | 1vyhN00 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 1110 — SGNH hydrolase |
| 结构域编号 domain_id | 1vyhO01 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 130 — 7 Propeller |
| 拓扑 Topology topology | 10 — Methylamine Dehydrogenase; Chain H |
| 同源超家族 H-superfamily homologous superfamily | 10 — YVTN repeat-like/Quinoprotein amine dehydrogenase |
| 结构域编号 domain_id | 1vyhP01 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 130 — 7 Propeller |
| 拓扑 Topology topology | 10 — Methylamine Dehydrogenase; Chain H |
| 同源超家族 H-superfamily homologous superfamily | 10 — YVTN repeat-like/Quinoprotein amine dehydrogenase |
| 结构域编号 domain_id | 1vyhQ00 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 1110 — SGNH hydrolase |
| 结构域编号 domain_id | 1vyhR00 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 1110 — SGNH hydrolase |
| 结构域编号 domain_id | 1vyhS01 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 130 — 7 Propeller |
| 拓扑 Topology topology | 10 — Methylamine Dehydrogenase; Chain H |
| 同源超家族 H-superfamily homologous superfamily | 10 — YVTN repeat-like/Quinoprotein amine dehydrogenase |
| 结构域编号 domain_id | 1vyhT01 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 130 — 7 Propeller |
| 拓扑 Topology topology | 10 — Methylamine Dehydrogenase; Chain H |
| 同源超家族 H-superfamily homologous superfamily | 10 — YVTN repeat-like/Quinoprotein amine dehydrogenase |