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1yvl

Structure of Unphosphorylated STAT1

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Signal transducer and activator of transcription 1-alpha/beta

Homo sapiens

UniProt P42224

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 2 5-residue peptide × 1 GOLD ION × 1 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 2 5-residue peptide × 1 GOLD ION × 1 Consistent with protein count
3 Protein heterocomplex Heteromer Protein 8 5-residue peptide × 4 GOLD ION × 4 Consistent with protein count
4 Protein heterocomplex Heteromer Protein 4 5-residue peptide × 2 GOLD ION × 2 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1bf5 1yvl 1yvl 1yvl 1yvl 2ka6 3wwt 7nuf 8d3f 8yyu 8yyu 8yyu

17 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name STAT1_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–683； UniProt 1–683 Author chain B； PDBConstruct 1–683； UniProt 1–683

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id1yvl
Deposition date deposition_date2005-02-16
Structure title titleStructure of Unphosphorylated STAT1
Keywords keywordsSIGNALING PROTEIN; SIGNALING PROTEIN
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

1yvl__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

1yvl__assembly_1__model_1 | I(q)

10-2 10-1 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

1yvl__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）35.71 Å
Rg (electron density)35.69 Å
Total Rg35.86 Å
Atom count5424
Residues656
Excluded volume96869 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 1yvl__assembly_1__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 1yvl__assembly_2__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
3 1 1yvl__assembly_3__model_1 octameric （8） Success 4.1.3-1-20251215 (887e7ef) View Download
4 1 1yvl__assembly_4__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

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6. Fold Classification (SCOP + CATH) 10 domains

CATH v4.4 (10 domains)

Domain ID domain_id1yvlA01
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology532 — Transcription Factor, Stat-4
Homologous superfamily homologous superfamily10 — STAT transcription factor, N-terminal domain
Domain ID domain_id1yvlA02
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology1050 — Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2
Homologous superfamily homologous superfamily20 — STAT transcription factor, all-alpha domain
Domain ID domain_id1yvlA03
Class class2 — Mainly Beta
Architecture architecture60 — Sandwich
Topology topology40 — Immunoglobulin-like
Homologous superfamily homologous superfamily630 — STAT transcription factor, DNA-binding domain
Domain ID domain_id1yvlA04
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology238 — Recoverin; domain 1
Homologous superfamily homologous superfamily10 — EF-hand
Domain ID domain_id1yvlA05
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology505 — SHC Adaptor Protein
Homologous superfamily homologous superfamily10 — SH2 domain
Domain ID domain_id1yvlB01
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology532 — Transcription Factor, Stat-4
Homologous superfamily homologous superfamily10 — STAT transcription factor, N-terminal domain
Domain ID domain_id1yvlB02
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology1050 — Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2
Homologous superfamily homologous superfamily20 — STAT transcription factor, all-alpha domain
Domain ID domain_id1yvlB03
Class class2 — Mainly Beta
Architecture architecture60 — Sandwich
Topology topology40 — Immunoglobulin-like
Homologous superfamily homologous superfamily630 — STAT transcription factor, DNA-binding domain
Domain ID domain_id1yvlB04
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology238 — Recoverin; domain 1
Homologous superfamily homologous superfamily10 — EF-hand
Domain ID domain_id1yvlB05
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology505 — SHC Adaptor Protein
Homologous superfamily homologous superfamily10 — SH2 domain
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7. Citations (1)