1zro

Crystal structure of EBA-175 Region II (RII) crystallized in the presence of (alpha)2,3-sialyllactose

Method: X-RAY DIFFRACTION Dmax: 139.6 Å Quality: GOOD

SAXS 散射曲线 SAXS Profile

SAXS profile for 1zro

P(r) 距离分布 P(r) Distribution

P(r) distribution for 1zro
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1. 结构基本信息 1. Structure Basics

条目编号 entry_id1zro
沉积日期 deposition_date2005-05-19
结构标题 titleCrystal structure of EBA-175 Region II (RII) crystallized in the presence of (alpha)2,3-sialyllactose
关键词 keywordsEBA-175, RII, DBL, erythrocyte, invasion, host, malaria, disease, glycophorin, glycan, sialic acid, sialyllactose, CELL INVASION; CELL INVASION
实验方法 methodX-RAY DIFFRACTION

2. SAXS 参数 (CRYSOL 理论计算) 2. SAXS Parameters (CRYSOL)

回转半径 Rg (Guinier) rg_guinier40.17
回转半径 Rg (电子) rg_electron39.74
零角强度 I(0) i0324810000.00
分子量 molecular_weight142650.0 kDa
排除体积 excluded_volume176830 ų
包络体积 envelope_volume249350 ų
水化壳体积 shell_volume52173 ų
包络直径 envelope_diameter147.6
壳层 Rg shell_rg45.47
包络 Rg envelope_rg39.14
形状 Rg shape_rg39.68
总 Rg total_rg40.23
总原子数 total_atoms9974
残基数 n_residues1176
球谐函数阶数 n_harmonics20
q 范围 q_range— – 0.5000 −1
数据点数 n_points101
壳层类型 shell_typedirectional
溶剂电子密度 solvent_density0.3340 e/ų
壳层衬度 contrast_shell0.0300 e/ų
CRYSOL 版本 crysol_version4.1.3

3. P(r) 距离分布 (GNOM 反演) 3. P(r) Analysis (GNOM)

最大尺寸 Dmax dmax139.6
Rg (实空间) rg_real40.15
Rg 误差 (实空间) rg_real_error1.36
I(0) (实空间) i0_real3.2480e+08
I(0) 误差 (实空间) i0_real_error6.1630e+06
Rg (倒空间) rg_reciprocal40.17
I(0) (倒空间) i0_reciprocal324800000.0000
解质量估计 total_estimate0.8816
解质量评级 solution_quality GOOD a GOOD solution
P(r) 峰数 n_peaks2
主峰位置 r_peak_primary53.7
偏度 Skewness skewness0.268
峰度 Kurtosis kurtosis-0.400
角度范围 angular_range— – 0.1950 −1
当前正则化参数 α current_alpha0.0000
最高正则化参数 α highest_alpha30780000.0000
实空间数据点数 n_real_points40
GNOM 版本 gnom_version4.1.3
质量判据 quality_criteria AN1: 0.000; Oscil: 0.846; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.952; Smooth: 0.966

4. 晶体学与实验 4. Crystallography & Experiment

5. 实体与聚合体信息 (4)

6. 折叠分类 (SCOP + CATH) 6 domains

SCOP 2.08 (4 domains)

结构域编号 domain_idd1zroa1
类 Class classa — All alpha proteins
折叠类型 Fold folda.264 — Duffy binding domain-like
超家族 Superfamily superfamilya.264.1 — Duffy binding domain-like
家族 Family familya.264.1.1 — Duffy binding domain
结构域编号 domain_idd1zroa2
类 Class classa — All alpha proteins
折叠类型 Fold folda.264 — Duffy binding domain-like
超家族 Superfamily superfamilya.264.1 — Duffy binding domain-like
家族 Family familya.264.1.1 — Duffy binding domain
结构域编号 domain_idd1zrob1
类 Class classa — All alpha proteins
折叠类型 Fold folda.264 — Duffy binding domain-like
超家族 Superfamily superfamilya.264.1 — Duffy binding domain-like
家族 Family familya.264.1.1 — Duffy binding domain
结构域编号 domain_idd1zrob2
类 Class classa — All alpha proteins
折叠类型 Fold folda.264 — Duffy binding domain-like
超家族 Superfamily superfamilya.264.1 — Duffy binding domain-like
家族 Family familya.264.1.1 — Duffy binding domain

CATH v4.4 (2 domains)

结构域编号 domain_id1zroA02
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily1660
结构域编号 domain_id1zroB02
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily1660

7. 引用文献 (1)

8. 文件与曲线 (10)