SAXSdb — 2avu

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1. Protein Identity and Related Structures Protein Identity & Related Structures

Transcriptional activator flhD

Escherichia coli

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 6	Flagellar transcriptional activator flhC × 2 （P0ABY7） ZINC ION × 2	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	FLHD_ECOLI
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain A； PDBConstruct 1–116； UniProt 1–116 Author chain B； PDBConstruct 1–116； UniProt 1–116 Author chain C； PDBConstruct 1–116； UniProt 1–116 Author chain D； PDBConstruct 1–116； UniProt 1–116

Flagellar transcriptional activator flhC

Escherichia coli

UniProt P0ABY7

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 6	Transcriptional activator flhD × 4 （P0A8S9） ZINC ION × 2	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	FLHC_ECOLI
Isoform	—
PDB entities	2
Chains and sequence ranges	Author chain E； PDBConstruct 1–192； UniProt 1–192 Author chain F； PDBConstruct 1–192； UniProt 1–192

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	2avu
Deposition date deposition_date	2005-08-30
Structure title title	Structure of the Escherichia coli FlhDC complex, a prokaryotic heteromeric regulator of transcription
Keywords keywords	C4-type Zinc finger, TRANSCRIPTION ACTIVATOR; TRANSCRIPTION ACTIVATOR
Experimental Method method	X-RAY DIFFRACTION

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

2avu__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

2avu__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

2avu__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	30.40 Å
Rg (electron density)	29.31 Å
Total Rg	30.05 Å
Atom count	5316
Residues	672
Excluded volume	95549 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`2avu__assembly_1__model_1`	hexameric （6）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

Entity 1 Entity 1 polymer

Description description	Transcriptional activator flhD
Molecular weight formula_weight	13333.4 kDa
Source method src_method	man
Copy count entity_count	4

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	A,B,C,D
Atom count atom_count	5316

MHTSELLKHIYDINLSYLLLAQRLIVQDKASAMFRLGINEEMATTLAALTLPQMVKLAETNQLVCHFRFDSHQTITQLTQDSRVDDLQQIHTGIMLSTRLLNDVNQPEEALRKKRA

Source Source

Source organism organism	Escherichia coli
NCBI taxonomy ID ncbi_taxonomy_id	562
Host organism host_organism	Escherichia coli BL21(DE3)

Entity 2 Entity 2 polymer

Description description	Flagellar transcriptional activator flhC
Molecular weight formula_weight	21589.1 kDa
Source method src_method	man
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	E,F

MSEKSIVQEARDIQLAMELITLGARLQMLESETQLSRGRLIKLYKELRGSPPPKGMLPFSTDWFMTWEQNVHASMFCNAWQFLLKTGLCNGVDAVIKAYRLYLEQCPQAEEGPLLALTRAWTLVRFVESGLLQLSSCNCCGGNFITHAHQPVGSFACSLCQPPSRAVKRRKLSQNPADIIPQLLDEQRVQAV

Source Source

Source organism organism	Escherichia coli
NCBI taxonomy ID ncbi_taxonomy_id	562
Host organism host_organism	Escherichia coli BL21(DE3)

Entity 3 Entity 3 non-polymer

Description description	ZINC ION
Molecular weight formula_weight	65.4 kDa
Source method src_method	syn
Copy count entity_count	2

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6. Fold Classification (SCOP + CATH) 10 domains

SCOP 2.08 (6 domains)

Domain ID domain_id	d2avua_
Class class	a — All alpha proteins
Fold Fold fold	a.145 — Flagellar transcriptional activator FlhD
Superfamily Superfamily superfamily	a.145.1 — Flagellar transcriptional activator FlhD
Family Family family	a.145.1.1 — Flagellar transcriptional activator FlhD

Domain ID domain_id	d2avub_
Class class	a — All alpha proteins
Fold Fold fold	a.145 — Flagellar transcriptional activator FlhD
Superfamily Superfamily superfamily	a.145.1 — Flagellar transcriptional activator FlhD
Family Family family	a.145.1.1 — Flagellar transcriptional activator FlhD

Domain ID domain_id	d2avuc_
Class class	a — All alpha proteins
Fold Fold fold	a.145 — Flagellar transcriptional activator FlhD
Superfamily Superfamily superfamily	a.145.1 — Flagellar transcriptional activator FlhD
Family Family family	a.145.1.1 — Flagellar transcriptional activator FlhD

Domain ID domain_id	d2avud_
Class class	a — All alpha proteins
Fold Fold fold	a.145 — Flagellar transcriptional activator FlhD
Superfamily Superfamily superfamily	a.145.1 — Flagellar transcriptional activator FlhD
Family Family family	a.145.1.1 — Flagellar transcriptional activator FlhD

Domain ID domain_id	d2avue1
Class class	e — Multi-domain proteins (alpha and beta)
Fold Fold fold	e.64 — FlhC-like
Superfamily Superfamily superfamily	e.64.1 — FlhC-like
Family Family family	e.64.1.1 — FlhC-like

Domain ID domain_id	d2avuf_
Class class	e — Multi-domain proteins (alpha and beta)
Fold Fold fold	e.64 — FlhC-like
Superfamily Superfamily superfamily	e.64.1 — FlhC-like
Family Family family	e.64.1.1 — FlhC-like

CATH v4.4 (4 domains)

Domain ID domain_id	2avuA00
Class class	1 — Mainly Alpha
Architecture architecture	10 — Orthogonal Bundle
Topology topology	4000 — Flagellar transcriptional activator fold
Homologous superfamily homologous superfamily	10 — Flagellar transcriptional activator FlhD

Domain ID domain_id	2avuB00
Class class	1 — Mainly Alpha
Architecture architecture	10 — Orthogonal Bundle
Topology topology	4000 — Flagellar transcriptional activator fold
Homologous superfamily homologous superfamily	10 — Flagellar transcriptional activator FlhD

Domain ID domain_id	2avuC00
Class class	1 — Mainly Alpha
Architecture architecture	10 — Orthogonal Bundle
Topology topology	4000 — Flagellar transcriptional activator fold
Homologous superfamily homologous superfamily	10 — Flagellar transcriptional activator FlhD

Domain ID domain_id	2avuD00
Class class	1 — Mainly Alpha
Architecture architecture	10 — Orthogonal Bundle
Topology topology	4000 — Flagellar transcriptional activator fold
Homologous superfamily homologous superfamily	10 — Flagellar transcriptional activator FlhD

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Unit-cell length a length_a	151.137 Å
Unit-cell length b length_b	151.137 Å
Unit-cell length c length_c	114.160 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	120.00 °
Molecules per unit cell Z z_pdb	24

Space group space_group	P 61
Space-group number int_tables_number	169
Crystal system crystal_system	—

Resolution resolution	3.000 Å
Low-resolution limit resolution_low	37.790 Å
R factor r_factor	0.2170
R_work r_work	0.2170
R_free r_free	0.2550

Structure of the Escherichia coli FlhDC complex, a prokaryotic heteromeric regulator of transcription

1. Protein Identity and Related Structures Protein Identity & Related Structures

Transcriptional activator flhD

State in the Current Structure

Other States of the Same Protein in the Database

Flagellar transcriptional activator flhC

State in the Current Structure

Other States of the Same Protein in the Database

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

2avu__assembly_1__model_1

2avu__assembly_1__model_1 | I(q)

2avu__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

5. Entities and Polymers Entities & Polymers (3)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 polymer

Polymer Polymer

Source Source

Entity 3 Entity 3 non-polymer

6. Fold Classification (SCOP + CATH) 10 domains

SCOP 2.08 (6 domains)

CATH v4.4 (4 domains)

7. Citations (1)

Structure of the Escherichia coli FlhDC complex, a prokaryotic heteromeric regulator of transcription

1. Protein Identity and Related Structures Protein Identity & Related Structures

Transcriptional activator flhD

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Flagellar transcriptional activator flhC

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

2avu__assembly_1__model_1

2avu__assembly_1__model_1 | I(q)

2avu__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

5. Entities and Polymers Entities & Polymers (3)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 polymer

Polymer Polymer

Source Source

Entity 3 Entity 3 non-polymer

6. Fold Classification (SCOP + CATH) 10 domains

SCOP 2.08 (6 domains)

CATH v4.4 (4 domains)

7. Citations (1)