2bdi

Human Kallikrein 4 complex with cobalt and p-aminobenzamidine

Method: X-RAY DIFFRACTION
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1. 蛋白身份与相关结构 Protein Identity & Related Structures

Kallikrein-4

Homo sapiens

UniProt Q9Y5K2

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白单体 单体 蛋白 1 COBALT (II) ION × 1 P-AMINO BENZAMIDINE × 1 water × 1 与蛋白数一致
10 蛋白单体 单体 蛋白 1 P-AMINO BENZAMIDINE × 1 water × 1 与蛋白数一致
11 蛋白单体 单体 蛋白 1 P-AMINO BENZAMIDINE × 1 water × 1 与蛋白数一致
12 蛋白单体 单体 蛋白 1 P-AMINO BENZAMIDINE × 1 water × 1 与蛋白数一致
13 蛋白单体 单体 蛋白 1 COBALT (II) ION × 1 P-AMINO BENZAMIDINE × 1 water × 1 与蛋白数一致
14 蛋白单体 单体 蛋白 1 P-AMINO BENZAMIDINE × 1 water × 1 与蛋白数一致
15 蛋白单体 单体 蛋白 1 P-AMINO BENZAMIDINE × 1 water × 1 与蛋白数一致
16 蛋白单体 单体 蛋白 1 P-AMINO BENZAMIDINE × 1 water × 1 与蛋白数一致
2 蛋白单体 单体 蛋白 1 P-AMINO BENZAMIDINE × 1 water × 1 与蛋白数一致
3 蛋白单体 单体 蛋白 1 P-AMINO BENZAMIDINE × 1 water × 1 与蛋白数一致
4 蛋白单体 单体 蛋白 1 P-AMINO BENZAMIDINE × 1 water × 1 与蛋白数一致
5 蛋白单体 单体 蛋白 1 COBALT (II) ION × 1 P-AMINO BENZAMIDINE × 1 water × 1 与蛋白数一致
6 蛋白单体 单体 蛋白 1 P-AMINO BENZAMIDINE × 1 water × 1 与蛋白数一致
7 蛋白单体 单体 蛋白 1 P-AMINO BENZAMIDINE × 1 water × 1 与蛋白数一致
8 蛋白单体 单体 蛋白 1 P-AMINO BENZAMIDINE × 1 water × 1 与蛋白数一致
9 蛋白单体 单体 蛋白 1 COBALT (II) ION × 1 P-AMINO BENZAMIDINE × 1 water × 1 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 KLK4_HUMAN
Isoform —
PDB实体 1
链与序列区间 作者链 A; PDB构建体 1–217; UniProt 27–45 作者链 B; PDB构建体 1–217; UniProt 27–45 作者链 C; PDB构建体 1–217; UniProt 27–45 作者链 D; PDB构建体 1–217; UniProt 27–45 作者链 E; PDB构建体 1–217; UniProt 27–45 作者链 F; PDB构建体 1–217; UniProt 27–45 作者链 G; PDB构建体 1–217; UniProt 27–45 作者链 H; PDB构建体 1–217; UniProt 27–45 作者链 I; PDB构建体 1–217; UniProt 27–45 作者链 J; PDB构建体 1–217; UniProt 27–45 作者链 K; PDB构建体 1–217; UniProt 27–45 作者链 L; PDB构建体 1–217; UniProt 27–45 作者链 M; PDB构建体 1–217; UniProt 27–45 作者链 N; PDB构建体 1–217; UniProt 27–45 作者链 O; PDB构建体 1–217; UniProt 27–45 作者链 P; PDB构建体 1–217; UniProt 27–45

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中;数据库内部编号、导入时间和 assembly 操作表达式仅用于维护,因此不在读者页面展示。

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2. 结构基本信息 2. Structure Basics

条目编号 entry_id2bdi
沉积日期 deposition_date2005-10-20
结构标题 titleHuman Kallikrein 4 complex with cobalt and p-aminobenzamidine
关键词 keywordsserine proteinase, s1 subsite, 70-80 loop, Structural Proteomics in Europe, SPINE, Structural Genomics, Hydrolase; HYDROLASE
实验方法 methodX-RAY DIFFRACTION
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3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

2bdi__assembly_6__model_1

Assembly 6 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

2bdi__assembly_6__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 个绘图点;横轴和纵轴均采用对数尺度。

2bdi__assembly_6__model_1 | P(r) · Pending

新版 assembly/model P(r) 尚未计算 此处仅保留位置,不展示旧数据 r (Angstrom) P(r)
P(r) 将按相同 assembly/model 分别计算和展示。
Rg(Guinier)17.44 Å
Rg(电子密度)16.23 Å
总 Rg17.23 Å
原子数1680
残基数223
排除体积29692 ų
最大 q0.500 Å⁻¹
Assembly Model 结构单元 聚集说明 状态 CRYSOL 操作
1 1 2bdi__assembly_1__model_1 monomeric (1) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
2 1 2bdi__assembly_2__model_1 monomeric (1) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
3 1 2bdi__assembly_3__model_1 monomeric (1) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
4 1 2bdi__assembly_4__model_1 monomeric (1) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
5 1 2bdi__assembly_5__model_1 monomeric (1) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
6 1 2bdi__assembly_6__model_1 monomeric (1) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
7 1 2bdi__assembly_7__model_1 monomeric (1) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
8 1 2bdi__assembly_8__model_1 monomeric (1) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
9 1 2bdi__assembly_9__model_1 monomeric (1) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
10 1 2bdi__assembly_10__model_1 monomeric (1) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
11 1 2bdi__assembly_11__model_1 monomeric (1) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
12 1 2bdi__assembly_12__model_1 monomeric (1) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
13 1 2bdi__assembly_13__model_1 monomeric (1) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
14 1 2bdi__assembly_14__model_1 monomeric (1) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
15 1 2bdi__assembly_15__model_1 monomeric (1) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
16 1 2bdi__assembly_16__model_1 monomeric (1) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
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4. 晶体学与实验 4. Crystallography & Experiment

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5. 实体与聚合物信息 Entities & Polymers (4)

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6. 折叠分类 (SCOP + CATH) 48 domains

SCOP 2.08 (16 domains)

结构域编号 domain_idd2bdia_
类 Class classb — All beta proteins
折叠类型 Fold foldb.47 — Trypsin-like serine proteases
超家族 Superfamily superfamilyb.47.1 — Trypsin-like serine proteases
家族 Family familyb.47.1.0 — automated matches
结构域编号 domain_idd2bdib_
类 Class classb — All beta proteins
折叠类型 Fold foldb.47 — Trypsin-like serine proteases
超家族 Superfamily superfamilyb.47.1 — Trypsin-like serine proteases
家族 Family familyb.47.1.0 — automated matches
结构域编号 domain_idd2bdic_
类 Class classb — All beta proteins
折叠类型 Fold foldb.47 — Trypsin-like serine proteases
超家族 Superfamily superfamilyb.47.1 — Trypsin-like serine proteases
家族 Family familyb.47.1.0 — automated matches
结构域编号 domain_idd2bdid_
类 Class classb — All beta proteins
折叠类型 Fold foldb.47 — Trypsin-like serine proteases
超家族 Superfamily superfamilyb.47.1 — Trypsin-like serine proteases
家族 Family familyb.47.1.0 — automated matches
结构域编号 domain_idd2bdie_
类 Class classb — All beta proteins
折叠类型 Fold foldb.47 — Trypsin-like serine proteases
超家族 Superfamily superfamilyb.47.1 — Trypsin-like serine proteases
家族 Family familyb.47.1.0 — automated matches
结构域编号 domain_idd2bdif_
类 Class classb — All beta proteins
折叠类型 Fold foldb.47 — Trypsin-like serine proteases
超家族 Superfamily superfamilyb.47.1 — Trypsin-like serine proteases
家族 Family familyb.47.1.0 — automated matches
结构域编号 domain_idd2bdig_
类 Class classb — All beta proteins
折叠类型 Fold foldb.47 — Trypsin-like serine proteases
超家族 Superfamily superfamilyb.47.1 — Trypsin-like serine proteases
家族 Family familyb.47.1.0 — automated matches
结构域编号 domain_idd2bdih_
类 Class classb — All beta proteins
折叠类型 Fold foldb.47 — Trypsin-like serine proteases
超家族 Superfamily superfamilyb.47.1 — Trypsin-like serine proteases
家族 Family familyb.47.1.0 — automated matches
结构域编号 domain_idd2bdii_
类 Class classb — All beta proteins
折叠类型 Fold foldb.47 — Trypsin-like serine proteases
超家族 Superfamily superfamilyb.47.1 — Trypsin-like serine proteases
家族 Family familyb.47.1.0 — automated matches
结构域编号 domain_idd2bdij_
类 Class classb — All beta proteins
折叠类型 Fold foldb.47 — Trypsin-like serine proteases
超家族 Superfamily superfamilyb.47.1 — Trypsin-like serine proteases
家族 Family familyb.47.1.0 — automated matches
结构域编号 domain_idd2bdik_
类 Class classb — All beta proteins
折叠类型 Fold foldb.47 — Trypsin-like serine proteases
超家族 Superfamily superfamilyb.47.1 — Trypsin-like serine proteases
家族 Family familyb.47.1.0 — automated matches
结构域编号 domain_idd2bdil_
类 Class classb — All beta proteins
折叠类型 Fold foldb.47 — Trypsin-like serine proteases
超家族 Superfamily superfamilyb.47.1 — Trypsin-like serine proteases
家族 Family familyb.47.1.0 — automated matches
结构域编号 domain_idd2bdim_
类 Class classb — All beta proteins
折叠类型 Fold foldb.47 — Trypsin-like serine proteases
超家族 Superfamily superfamilyb.47.1 — Trypsin-like serine proteases
家族 Family familyb.47.1.0 — automated matches
结构域编号 domain_idd2bdin_
类 Class classb — All beta proteins
折叠类型 Fold foldb.47 — Trypsin-like serine proteases
超家族 Superfamily superfamilyb.47.1 — Trypsin-like serine proteases
家族 Family familyb.47.1.0 — automated matches
结构域编号 domain_idd2bdio_
类 Class classb — All beta proteins
折叠类型 Fold foldb.47 — Trypsin-like serine proteases
超家族 Superfamily superfamilyb.47.1 — Trypsin-like serine proteases
家族 Family familyb.47.1.0 — automated matches
结构域编号 domain_idd2bdip_
类 Class classb — All beta proteins
折叠类型 Fold foldb.47 — Trypsin-like serine proteases
超家族 Superfamily superfamilyb.47.1 — Trypsin-like serine proteases
家族 Family familyb.47.1.0 — automated matches

CATH v4.4 (32 domains)

结构域编号 domain_id2bdiA01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology10 — Thrombin, subunit H
同源超家族 H-superfamily homologous superfamily10 — Trypsin-like serine proteases
结构域编号 domain_id2bdiA02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology10 — Thrombin, subunit H
同源超家族 H-superfamily homologous superfamily10 — Trypsin-like serine proteases
结构域编号 domain_id2bdiB01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology10 — Thrombin, subunit H
同源超家族 H-superfamily homologous superfamily10 — Trypsin-like serine proteases
结构域编号 domain_id2bdiB02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology10 — Thrombin, subunit H
同源超家族 H-superfamily homologous superfamily10 — Trypsin-like serine proteases
结构域编号 domain_id2bdiC01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology10 — Thrombin, subunit H
同源超家族 H-superfamily homologous superfamily10 — Trypsin-like serine proteases
结构域编号 domain_id2bdiC02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology10 — Thrombin, subunit H
同源超家族 H-superfamily homologous superfamily10 — Trypsin-like serine proteases
结构域编号 domain_id2bdiD01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology10 — Thrombin, subunit H
同源超家族 H-superfamily homologous superfamily10 — Trypsin-like serine proteases
结构域编号 domain_id2bdiD02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology10 — Thrombin, subunit H
同源超家族 H-superfamily homologous superfamily10 — Trypsin-like serine proteases
结构域编号 domain_id2bdiE01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology10 — Thrombin, subunit H
同源超家族 H-superfamily homologous superfamily10 — Trypsin-like serine proteases
结构域编号 domain_id2bdiE02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology10 — Thrombin, subunit H
同源超家族 H-superfamily homologous superfamily10 — Trypsin-like serine proteases
结构域编号 domain_id2bdiF01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology10 — Thrombin, subunit H
同源超家族 H-superfamily homologous superfamily10 — Trypsin-like serine proteases
结构域编号 domain_id2bdiF02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology10 — Thrombin, subunit H
同源超家族 H-superfamily homologous superfamily10 — Trypsin-like serine proteases
结构域编号 domain_id2bdiG01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology10 — Thrombin, subunit H
同源超家族 H-superfamily homologous superfamily10 — Trypsin-like serine proteases
结构域编号 domain_id2bdiG02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology10 — Thrombin, subunit H
同源超家族 H-superfamily homologous superfamily10 — Trypsin-like serine proteases
结构域编号 domain_id2bdiH01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology10 — Thrombin, subunit H
同源超家族 H-superfamily homologous superfamily10 — Trypsin-like serine proteases
结构域编号 domain_id2bdiH02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology10 — Thrombin, subunit H
同源超家族 H-superfamily homologous superfamily10 — Trypsin-like serine proteases
结构域编号 domain_id2bdiI01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology10 — Thrombin, subunit H
同源超家族 H-superfamily homologous superfamily10 — Trypsin-like serine proteases
结构域编号 domain_id2bdiI02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology10 — Thrombin, subunit H
同源超家族 H-superfamily homologous superfamily10 — Trypsin-like serine proteases
结构域编号 domain_id2bdiJ01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology10 — Thrombin, subunit H
同源超家族 H-superfamily homologous superfamily10 — Trypsin-like serine proteases
结构域编号 domain_id2bdiJ02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology10 — Thrombin, subunit H
同源超家族 H-superfamily homologous superfamily10 — Trypsin-like serine proteases
结构域编号 domain_id2bdiK01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology10 — Thrombin, subunit H
同源超家族 H-superfamily homologous superfamily10 — Trypsin-like serine proteases
结构域编号 domain_id2bdiK02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology10 — Thrombin, subunit H
同源超家族 H-superfamily homologous superfamily10 — Trypsin-like serine proteases
结构域编号 domain_id2bdiL01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology10 — Thrombin, subunit H
同源超家族 H-superfamily homologous superfamily10 — Trypsin-like serine proteases
结构域编号 domain_id2bdiL02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology10 — Thrombin, subunit H
同源超家族 H-superfamily homologous superfamily10 — Trypsin-like serine proteases
结构域编号 domain_id2bdiM01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology10 — Thrombin, subunit H
同源超家族 H-superfamily homologous superfamily10 — Trypsin-like serine proteases
结构域编号 domain_id2bdiM02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology10 — Thrombin, subunit H
同源超家族 H-superfamily homologous superfamily10 — Trypsin-like serine proteases
结构域编号 domain_id2bdiN01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology10 — Thrombin, subunit H
同源超家族 H-superfamily homologous superfamily10 — Trypsin-like serine proteases
结构域编号 domain_id2bdiN02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology10 — Thrombin, subunit H
同源超家族 H-superfamily homologous superfamily10 — Trypsin-like serine proteases
结构域编号 domain_id2bdiO01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology10 — Thrombin, subunit H
同源超家族 H-superfamily homologous superfamily10 — Trypsin-like serine proteases
结构域编号 domain_id2bdiO02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology10 — Thrombin, subunit H
同源超家族 H-superfamily homologous superfamily10 — Trypsin-like serine proteases
结构域编号 domain_id2bdiP01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology10 — Thrombin, subunit H
同源超家族 H-superfamily homologous superfamily10 — Trypsin-like serine proteases
结构域编号 domain_id2bdiP02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology10 — Thrombin, subunit H
同源超家族 H-superfamily homologous superfamily10 — Trypsin-like serine proteases
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7. 引用文献 (1)