HOMO SAPIENS
| Assembly | 物理组成 | 蛋白状态 | 分子拷贝数 | 共同组分 | 数据核对 |
|---|---|---|---|---|---|
| 1 | 蛋白–DNA | 同源多聚体 | 蛋白 2 DNA 1 | ;5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP *TP*TP*TP*TP*TP*TP*TP*TP*TP*G)-3' ; × 1 SULFATE ION × 2 water × 3 | 与全部聚合物一致 |
| UniProt名称 | TCP4_HUMAN |
| Isoform | — |
| PDB实体 | 1 |
| 链与序列区间 | 作者链 A； PDB构建体 2–66； UniProt 62–126 作者链 B； PDB构建体 2–66； UniProt 62–126 |
页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。
| 条目编号 entry_id | 2c62 |
| 沉积日期 deposition_date | 2005-11-07 |
| 结构标题 title | Crystal Structure of the Human Transcription Cofactor PC4 in Complex with Single-Stranded DNA |
| 关键词 keywords | ;TRANSCRIPTION COFACTOR, SINGLE-STRANDED DNA, PROTEIN-DNA COMPLEX, DNA UNWINDING, ACTIVATOR, DNA-BINDING, NUCLEAR PROTEIN, PHOSPHORYLATION, TRANSCRIPTION, TRANSCRIPTION REGULATION ;; TRANSCRIPTION |
| 实验方法 method | X-RAY DIFFRACTION |
页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 16.92 Å |
| Rg（电子密度） | 15.75 Å |
| 总 Rg | 16.74 Å |
| 原子数 | 1423 |
| 残基数 | 148 |
| 排除体积 | 24647 ų |
| 最大 q | 0.500 Å⁻¹ |
| 结构域编号 domain_id | d2c62a2 |
| 类 Class class | d — Alpha and beta proteins (a+b) |
| 折叠类型 Fold fold | d.18 — ssDNA-binding transcriptional regulator domain |
| 超家族 Superfamily superfamily | d.18.1 — ssDNA-binding transcriptional regulator domain |
| 家族 Family family | d.18.1.1 — Transcriptional coactivator PC4 C-terminal domain |
| 结构域编号 domain_id | d2c62a3 |
| 类 Class class | l — Artifacts |
| 折叠类型 Fold fold | l.1 — Tags |
| 超家族 Superfamily superfamily | l.1.1 — Tags |
| 家族 Family family | l.1.1.1 — Tags |
| 结构域编号 domain_id | d2c62b2 |
| 类 Class class | d — Alpha and beta proteins (a+b) |
| 折叠类型 Fold fold | d.18 — ssDNA-binding transcriptional regulator domain |
| 超家族 Superfamily superfamily | d.18.1 — ssDNA-binding transcriptional regulator domain |
| 家族 Family family | d.18.1.1 — Transcriptional coactivator PC4 C-terminal domain |
| 结构域编号 domain_id | d2c62b3 |
| 类 Class class | l — Artifacts |
| 折叠类型 Fold fold | l.1 — Tags |
| 超家族 Superfamily superfamily | l.1.1 — Tags |
| 家族 Family family | l.1.1.1 — Tags |
| 结构域编号 domain_id | 2c62A00 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 30 — Roll |
| 拓扑 Topology topology | 31 — Transcriptional Co-activator pc4; Chain A |
| 同源超家族 H-superfamily homologous superfamily | 10 — Transcriptional Coactivator Pc4; Chain A |
| 结构域编号 domain_id | 2c62B00 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 30 — Roll |
| 拓扑 Topology topology | 31 — Transcriptional Co-activator pc4; Chain A |
| 同源超家族 H-superfamily homologous superfamily | 10 — Transcriptional Coactivator Pc4; Chain A |