Thermus thermophilus
| Assembly | 物理组成 | 蛋白状态 | 分子拷贝数 | 共同组分 | 数据核对 |
|---|---|---|---|---|---|
| 1 | 蛋白同源多聚体 | 同源多聚体 | 蛋白 2 | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE × 2 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL × 4 water × 2 | 与蛋白数一致 |
| UniProt名称 | MDH_THETH |
| Isoform | — |
| PDB实体 | 1 |
| 链与序列区间 | 作者链 A； PDB构建体 1–321； UniProt 1–327 作者链 B； PDB构建体 1–321； UniProt 1–327 |
页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。
| 条目编号 entry_id | 2cvq |
| 沉积日期 deposition_date | 2005-06-13 |
| 结构标题 title | Crystal structure of NAD(H)-dependent malate dehydrogenase complexed with NADPH |
| 关键词 keywords | NAD-dependent-MDH NADP+ complex, OXIDOREDUCTASE; OXIDOREDUCTASE |
| 实验方法 method | X-RAY DIFFRACTION |
页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 26.94 Å |
| Rg（电子密度） | 26.19 Å |
| 总 Rg | 26.92 Å |
| 原子数 | 5088 |
| 残基数 | 654 |
| 排除体积 | 90777 ų |
| 最大 q | 0.500 Å⁻¹ |
| 结构域编号 domain_id | d2cvqa1 |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.2 — NAD(P)-binding Rossmann-fold domains |
| 超家族 Superfamily superfamily | c.2.1 — NAD(P)-binding Rossmann-fold domains |
| 家族 Family family | c.2.1.5 — LDH N-terminal domain-like |
| 结构域编号 domain_id | d2cvqa2 |
| 类 Class class | d — Alpha and beta proteins (a+b) |
| 折叠类型 Fold fold | d.162 — LDH C-terminal domain-like |
| 超家族 Superfamily superfamily | d.162.1 — LDH C-terminal domain-like |
| 家族 Family family | d.162.1.1 — Lactate & malate dehydrogenases, C-terminal domain |
| 结构域编号 domain_id | d2cvqb1 |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.2 — NAD(P)-binding Rossmann-fold domains |
| 超家族 Superfamily superfamily | c.2.1 — NAD(P)-binding Rossmann-fold domains |
| 家族 Family family | c.2.1.5 — LDH N-terminal domain-like |
| 结构域编号 domain_id | d2cvqb2 |
| 类 Class class | d — Alpha and beta proteins (a+b) |
| 折叠类型 Fold fold | d.162 — LDH C-terminal domain-like |
| 超家族 Superfamily superfamily | d.162.1 — LDH C-terminal domain-like |
| 家族 Family family | d.162.1.1 — Lactate & malate dehydrogenases, C-terminal domain |
| 结构域编号 domain_id | 2cvqA01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 720 — NAD(P)-binding Rossmann-like Domain |
| 结构域编号 domain_id | 2cvqA02 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 90 — Alpha-Beta Complex |
| 拓扑 Topology topology | 110 — L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2 |
| 同源超家族 H-superfamily homologous superfamily | 10 — Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal |
| 结构域编号 domain_id | 2cvqB01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 720 — NAD(P)-binding Rossmann-like Domain |
| 结构域编号 domain_id | 2cvqB02 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 90 — Alpha-Beta Complex |
| 拓扑 Topology topology | 110 — L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2 |
| 同源超家族 H-superfamily homologous superfamily | 10 — Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal |