2eze

SOLUTION STRUCTURE OF A COMPLEX OF THE SECOND DNA BINDING DOMAIN OF HUMAN HMG-I(Y) BOUND TO DNA DODECAMER CONTAINING THE PRDII SITE OF THE INTERFERON-BETA PROMOTER, NMR, 35 STRUCTURES

Method: SOLUTION NMR

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1. Protein Identity and Related Structures Protein Identity & Related Structures

HIGH MOBILITY GROUP PROTEIN HMG-I/HMG-Y

Homo sapiens

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–DNA	Monomer	Protein 1 DNA 2	;DNA (5'-D(GPGPGPAPAPAPTPTPCPCPTPC)-3') ; × 1 ;DNA (5'-D(GPAPGPGPAPAPTPTPTPCPCPC)-3') ; × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	HMGIY_HUMAN
Isoform	—
PDB entities	3
Chains and sequence ranges	Author chain A； PDBConstruct 1–25； UniProt 39–63

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	2eze
Deposition date deposition_date	1997-06-04
Structure title title	SOLUTION STRUCTURE OF A COMPLEX OF THE SECOND DNA BINDING DOMAIN OF HUMAN HMG-I(Y) BOUND TO DNA DODECAMER CONTAINING THE PRDII SITE OF THE INTERFERON-BETA PROMOTER, NMR, 35 STRUCTURES
Keywords keywords	;DNA BINDING PROTEIN, MINOR GROOVE DNA BINDING, TRANSCRIPTIONAL CO-ACTIVATOR, ARCHITECTURAL FACTOR, COMPLEX (DNA-BINDING PROTEIN-DNA), DNA BINDING PROTEIN-DNA COMPLEX ;; DNA BINDING PROTEIN/DNA
Experimental Method method	SOLUTION NMR

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

2eze__assembly_1__model_27

Assembly 1 · Model 27 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

2eze__assembly_1__model_27 | I(q)

100 plotted points; both axes use logarithmic scales.

2eze__assembly_1__model_27 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	15.64 Å
Rg (electron density)	15.36 Å
Total Rg	16.11 Å
Atom count	1168
Residues	49
Excluded volume	10521 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`2eze__assembly_1__model_1`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	2	`2eze__assembly_1__model_2`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	3	`2eze__assembly_1__model_3`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	4	`2eze__assembly_1__model_4`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	5	`2eze__assembly_1__model_5`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	6	`2eze__assembly_1__model_6`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	7	`2eze__assembly_1__model_7`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	8	`2eze__assembly_1__model_8`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	9	`2eze__assembly_1__model_9`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	10	`2eze__assembly_1__model_10`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	11	`2eze__assembly_1__model_11`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	12	`2eze__assembly_1__model_12`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	13	`2eze__assembly_1__model_13`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	14	`2eze__assembly_1__model_14`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	15	`2eze__assembly_1__model_15`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	16	`2eze__assembly_1__model_16`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	17	`2eze__assembly_1__model_17`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	18	`2eze__assembly_1__model_18`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	19	`2eze__assembly_1__model_19`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	20	`2eze__assembly_1__model_20`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	21	`2eze__assembly_1__model_21`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	22	`2eze__assembly_1__model_22`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	23	`2eze__assembly_1__model_23`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	24	`2eze__assembly_1__model_24`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	25	`2eze__assembly_1__model_25`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	26	`2eze__assembly_1__model_26`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	27	`2eze__assembly_1__model_27`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	28	`2eze__assembly_1__model_28`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	29	`2eze__assembly_1__model_29`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	30	`2eze__assembly_1__model_30`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	31	`2eze__assembly_1__model_31`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	32	`2eze__assembly_1__model_32`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	33	`2eze__assembly_1__model_33`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	34	`2eze__assembly_1__model_34`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download
1	35	`2eze__assembly_1__model_35`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

Entity 1 Entity 1 polymer

Description description	;DNA (5'-D(GPGPGPAPAPAPTPTPCPCPTPC)-3') ;
Molecular weight formula_weight	3662.4 kDa
Source method src_method	syn
Copy count entity_count	1

Polymer Polymer

Polymer type type	polydeoxyribonucleotide
Chain IDs strand_id	B
Atom count atom_count	40880

GGGAAATTCCTC

Entity 2 Entity 2 polymer

Description description	;DNA (5'-D(GPAPGPGPAPAPTPTPTPCPCPC)-3') ;
Molecular weight formula_weight	3662.4 kDa
Source method src_method	syn
Copy count entity_count	1

Polymer Polymer

Polymer type type	polydeoxyribonucleotide
Chain IDs strand_id	C

GAGGAATTTCCC

Entity 3 Entity 3 polymer

Description description	HIGH MOBILITY GROUP PROTEIN HMG-I/HMG-Y
Molecular weight formula_weight	2727.3 kDa
Source method src_method	man
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	A

VPTPKRPRGRPKGSKNKGAAKTRKT

Source Source

Source organism organism	Homo sapiens
Common name common_name	human
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	Escherichia coli

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6. Fold Classification (SCOP + CATH) 1 domains

SCOP 2.08 (1 domains)

Domain ID domain_id	d2ezea_
Class class	j — Peptides
Fold Fold fold	j.10 — DNA-binding domains of HMG-I(Y)
Superfamily Superfamily superfamily	j.10.1 — DNA-binding domains of HMG-I(Y)
Family Family family	j.10.1.1 — DNA-binding domains of HMG-I(Y)

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Unit-cell length a length_a	1.000 Å
Unit-cell length b length_b	1.000 Å
Unit-cell length c length_c	1.000 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	1

Space group space_group	P 1
Space-group number int_tables_number	1
Crystal system crystal_system	—

SOLUTION STRUCTURE OF A COMPLEX OF THE SECOND DNA BINDING DOMAIN OF HUMAN HMG-I(Y) BOUND TO DNA DODECAMER CONTAINING THE PRDII SITE OF THE INTERFERON-BETA PROMOTER, NMR, 35 STRUCTURES

1. Protein Identity and Related Structures Protein Identity & Related Structures

HIGH MOBILITY GROUP PROTEIN HMG-I/HMG-Y

State in the Current Structure

Other States of the Same Protein in the Database

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

2eze__assembly_1__model_27

2eze__assembly_1__model_27 | I(q)

2eze__assembly_1__model_27 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

5. Entities and Polymers Entities & Polymers (3)

Entity 1 Entity 1 polymer

Polymer Polymer

Entity 2 Entity 2 polymer

Polymer Polymer

Entity 3 Entity 3 polymer

Polymer Polymer

Source Source

6. Fold Classification (SCOP + CATH) 1 domains

SCOP 2.08 (1 domains)

7. Citations (1)

SOLUTION STRUCTURE OF A COMPLEX OF THE SECOND DNA BINDING DOMAIN OF HUMAN HMG-I(Y) BOUND TO DNA DODECAMER CONTAINING THE PRDII SITE OF THE INTERFERON-BETA PROMOTER, NMR, 35 STRUCTURES

1. Protein Identity and Related Structures Protein Identity & Related Structures

HIGH MOBILITY GROUP PROTEIN HMG-I/HMG-Y

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

2eze__assembly_1__model_27

2eze__assembly_1__model_27 | I(q)

2eze__assembly_1__model_27 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

5. Entities and Polymers Entities & Polymers (3)

Entity 1 Entity 1 polymer

Polymer Polymer

Entity 2 Entity 2 polymer

Polymer Polymer

Entity 3 Entity 3 polymer

Polymer Polymer

Source Source

6. Fold Classification (SCOP + CATH) 1 domains

SCOP 2.08 (1 domains)

7. Citations (1)