Escherichia coli
| Assembly | Physical composition | Protein state | Molecular copy count | Associated components | Data consistency |
|---|---|---|---|---|---|
| 1 | Protein homooligomer | Homooligomer | Protein 2 | SULFATE ION × 16 water × 2 | Consistent with protein count |
| UniProt name | TYSY_ECOLI |
| Isoform | — |
| PDB entities | 1 |
| Chains and sequence ranges | Author chain A； PDBConstruct 1–264； UniProt 1–264 |
The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.
| Entry ID entry_id | 2ftn |
| Deposition date deposition_date | 2006-01-24 |
| Structure title title | E. coli thymidylate synthase Y94F mutant |
| Keywords keywords | methyltransferase, TRANSFERASE; TRANSFERASE |
| Experimental Method method | X-RAY DIFFRACTION |
This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 24.94 Å |
| Rg (electron density) | 23.28 Å |
| Total Rg | 24.31 Å |
| Atom count | 4384 |
| Residues | 526 |
| Excluded volume | 77143 ų |
| Maximum q | 0.500 Å⁻¹ |
| Domain ID domain_id | d2ftna_ |
| Class class | d — Alpha and beta proteins (a+b) |
| Fold Fold fold | d.117 — Thymidylate synthase/dCMP hydroxymethylase |
| Superfamily Superfamily superfamily | d.117.1 — Thymidylate synthase/dCMP hydroxymethylase |
| Family Family family | d.117.1.1 — Thymidylate synthase/dCMP hydroxymethylase |
| Domain ID domain_id | 2ftnA00 |
| Class class | 3 — Alpha Beta |
| Architecture architecture | 30 — 2-Layer Sandwich |
| Topology topology | 572 — Thymidylate Synthase; Chain A |
| Homologous superfamily homologous superfamily | 10 — Thymidylate synthase/dCMP hydroxymethylase domain |