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2hb5

Crystal Structure of the Moloney Murine Leukemia Virus RNase H Domain

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Reverse transcriptase/ribonuclease H

Moloney murine leukemia virus

UniProt P03355

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein monomer Monomer Protein 1 MAGNESIUM ION × 1 SULFATE ION × 1 water × 1 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1nnd 2hb5 2m9u 4mh8

4 assemblies

Homodimer
1mml 4nzg 4nzg

3 assemblies

Homotetramer
3nnq 4nzg

2 assemblies

Other homooligomers

None

Heteromeric or nucleic-acid complex
1d0e 1d1u 1i6j 1n4l 1qai 1qaj 1ztt 1ztw 2fjv 2fjw 2fjx 2fvp

38 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name POL_MLVMO
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 2–164； UniProt 618–791

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id2hb5
Deposition date deposition_date2006-06-13
Structure title titleCrystal Structure of the Moloney Murine Leukemia Virus RNase H Domain
Keywords keywordsRNase H, HYDROLASE; HYDROLASE
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

2hb5__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

2hb5__assembly_1__model_1 | I(q)

10-2 10-1 105 106 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

2hb5__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）16.22 Å
Rg (electron density)15.11 Å
Total Rg16.18 Å
Atom count1139
Residues148
Excluded volume20149 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 2hb5__assembly_1__model_1 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (4)

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6. Fold Classification (SCOP + CATH) 2 domains

SCOP 2.08 (1 domains)

Domain ID domain_idd2hb5a_
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.55 — Ribonuclease H-like motif
Superfamily Superfamily superfamilyc.55.3 — Ribonuclease H-like
Family Family familyc.55.3.0 — automated matches

CATH v4.4 (1 domains)

Domain ID domain_id2hb5A00
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology420 — Nucleotidyltransferase; domain 5
Homologous superfamily homologous superfamily10 — Ribonuclease H-like superfamily/Ribonuclease H
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7. Citations (1)