2hnw

Crystal Structure of the F91STOP mutant of des1-6 Bovine Neurophysin-I, unliganded state

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Oxytocin-neurophysin 1

Bos taurus

UniProt P01175

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 2 No other associated polymer Consistent with protein count
2 Protein homooligomer Homooligomer Protein 2 No other associated polymer Consistent with protein count
3 Protein homooligomer Homooligomer Protein 2 No other associated polymer Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name NEU1_BOVIN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 1–80; UniProt 38–117 Author chain B; PDBConstruct 1–80; UniProt 38–117 Author chain C; PDBConstruct 1–80; UniProt 38–117 Author chain D; PDBConstruct 1–80; UniProt 38–117 Author chain E; PDBConstruct 1–80; UniProt 38–117

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id2hnw
Deposition date deposition_date2006-07-13
Structure title titleCrystal Structure of the F91STOP mutant of des1-6 Bovine Neurophysin-I, unliganded state
Keywords keywords;unliganded bovine neurophysin-I, des1-6, F91STOP mutations, inter-domain loop, disulfides, beta sheet, 3, 10 helix, subunit interface, PEPTIDE BINDING PROTEIN ;; PEPTIDE BINDING PROTEIN
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

2hnw__assembly_3__model_1

Assembly 3 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

2hnw__assembly_3__model_1 | I(q)

10-2 10-1 105 106 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

2hnw__assembly_3__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)15.80 Å
Rg (electron density)15.26 Å
Total Rg16.02 Å
Atom count1102
Residues160
Excluded volume19058 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 2hnw__assembly_1__model_1 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 2hnw__assembly_2__model_1 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
3 1 2hnw__assembly_3__model_1 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (1)

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6. Fold Classification (SCOP + CATH) 10 domains

SCOP 2.08 (5 domains)

Domain ID domain_idd2hnwa_
Class classb — All beta proteins
Fold Fold foldb.9 — Neurophysin II
Superfamily Superfamily superfamilyb.9.1 — Neurophysin II
Family Family familyb.9.1.1 — Neurophysin II
Domain ID domain_idd2hnwb_
Class classb — All beta proteins
Fold Fold foldb.9 — Neurophysin II
Superfamily Superfamily superfamilyb.9.1 — Neurophysin II
Family Family familyb.9.1.1 — Neurophysin II
Domain ID domain_idd2hnwc_
Class classb — All beta proteins
Fold Fold foldb.9 — Neurophysin II
Superfamily Superfamily superfamilyb.9.1 — Neurophysin II
Family Family familyb.9.1.1 — Neurophysin II
Domain ID domain_idd2hnwd_
Class classb — All beta proteins
Fold Fold foldb.9 — Neurophysin II
Superfamily Superfamily superfamilyb.9.1 — Neurophysin II
Family Family familyb.9.1.1 — Neurophysin II
Domain ID domain_idd2hnwe_
Class classb — All beta proteins
Fold Fold foldb.9 — Neurophysin II
Superfamily Superfamily superfamilyb.9.1 — Neurophysin II
Family Family familyb.9.1.1 — Neurophysin II

CATH v4.4 (5 domains)

Domain ID domain_id2hnwA00
Class class2 — Mainly Beta
Architecture architecture60 — Sandwich
Topology topology9 — Neurophysin II; Chain A
Homologous superfamily homologous superfamily10 — Neurohypophysial hormone domain
Domain ID domain_id2hnwB00
Class class2 — Mainly Beta
Architecture architecture60 — Sandwich
Topology topology9 — Neurophysin II; Chain A
Homologous superfamily homologous superfamily10 — Neurohypophysial hormone domain
Domain ID domain_id2hnwC00
Class class2 — Mainly Beta
Architecture architecture60 — Sandwich
Topology topology9 — Neurophysin II; Chain A
Homologous superfamily homologous superfamily10 — Neurohypophysial hormone domain
Domain ID domain_id2hnwD00
Class class2 — Mainly Beta
Architecture architecture60 — Sandwich
Topology topology9 — Neurophysin II; Chain A
Homologous superfamily homologous superfamily10 — Neurohypophysial hormone domain
Domain ID domain_id2hnwE00
Class class2 — Mainly Beta
Architecture architecture60 — Sandwich
Topology topology9 — Neurophysin II; Chain A
Homologous superfamily homologous superfamily10 — Neurohypophysial hormone domain
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7. Citations (1)