2hv2

Crystal Structure of Conserved Protein of Unknown Function from Enterococcus faecalis V583 at 2.4 A Resolution, Probable N-Acyltransferase

Method: X-RAY DIFFRACTION

▼

1. 蛋白身份与相关结构 Protein Identity & Related Structures

Hypothetical protein

Enterococcus faecalis

当前结构中的状态

Assembly	物理组成	蛋白状态	分子拷贝数	共同组分	数据核对
1	蛋白同源多聚体	同源多聚体	蛋白 6	4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID × 5 TETRAETHYLENE GLYCOL × 6 water × 6	与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据

UniProt名称	Q836T6_ENTFA
Isoform	—
PDB实体	1
链与序列区间	作者链 A； PDB构建体 4–400； UniProt 1–397 作者链 B； PDB构建体 4–400； UniProt 1–397 作者链 C； PDB构建体 4–400； UniProt 1–397 作者链 D； PDB构建体 4–400； UniProt 1–397 作者链 E； PDB构建体 4–400； UniProt 1–397 作者链 F； PDB构建体 4–400； UniProt 1–397

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。

▼

2. 结构基本信息 2. Structure Basics

条目编号 entry_id	2hv2
沉积日期 deposition_date	2006-07-27
结构标题 title	Crystal Structure of Conserved Protein of Unknown Function from Enterococcus faecalis V583 at 2.4 A Resolution, Probable N-Acyltransferase
关键词 keywords	PSI, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, Structural Genomics, UNKNOWN FUNCTION; STRUCTURAL GENOMICS, UNKNOWN FUNCTION
实验方法 method	X-RAY DIFFRACTION

▼

3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

2hv2__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

2hv2__assembly_1__model_1 | I(q)

100 个绘图点；横轴和纵轴均采用对数尺度。

2hv2__assembly_1__model_1 | P(r) · Pending

P(r) 将按相同 assembly/model 分别计算和展示。

Rg（Guinier）	42.78 Å
Rg（电子密度）	42.01 Å
总 Rg	42.48 Å
原子数	19146
残基数	2279
排除体积	342650 Å³
最大 q	0.500 Å⁻¹

Assembly	Model	结构单元	聚集说明	状态	CRYSOL	操作
1	1	`2hv2__assembly_1__model_1`	hexameric （6）	成功	4.1.3-1-20251215 (887e7ef)	查看下载

▶

4. 晶体学与实验 4. Crystallography & Experiment

▶

5. 实体与聚合物信息 Entities & Polymers (4)

实体 1 Entity 1 polymer

描述 description	Hypothetical protein
分子量 formula_weight	46251.3 kDa
来源方法 src_method	man
拷贝数 entity_count	6

聚合物 Polymer

聚合物类型 type	polypeptide(L)
链编号 strand_id	A,B,C,D,E,F
原子数 atom_count	19692

SNAMTTKRVKKMGKEEMKEMFDLVIYAFNQEPTAERQERFEKLLSHTQSYGFLIDEQLTSQVMATPFQVNFHGVRYPMAGIGYVASYPEYRGEGGISAIMKEMLADLAKQKVALSYLAPFSYPFYRQYGYEQTFEQAEYTIKTEDWPRVKRVPGTIKRVSWADGKEVIKDVYLENQRAHSGGVIRETWWLDYTLNRASKPNNQAIYYSSEGKAEGYVIYRIAAGTFEIVEWNYLTNTAFKALAGFIGSHSGSVQSFHWINGFAGKDLNDLMPTPAASVKILPYMMARIVELQTFLEKYPFQSGEKETYSLEIEDSYGPWNEGIWTITIDEQGKATVTKGAAEKEGTAALKADIQTWTQLFLGYRSAETLSFYERLQGDATIAQRLGQRLVKGMPILEDYF

来源 Source

来源生物 organism	Enterococcus faecalis
NCBI 分类编号 ncbi_taxonomy_id	1351
宿主生物 host_organism	Escherichia coli

实体 2 Entity 2 non-polymer

描述 description	4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
分子量 formula_weight	238.3 kDa
来源方法 src_method	syn
拷贝数 entity_count	5

实体 3 Entity 3 non-polymer

描述 description	TETRAETHYLENE GLYCOL
分子量 formula_weight	194.2 kDa
来源方法 src_method	syn
拷贝数 entity_count	6

实体 4 Entity 4 water

描述 description	water
分子量 formula_weight	18.0 kDa
来源方法 src_method	nat
拷贝数 entity_count	541

▼

6. 折叠分类 (SCOP + CATH) 30 domains

SCOP 2.08 (12 domains)

结构域编号 domain_id	d2hv2a1
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.106 — SCP-like
超家族 Superfamily superfamily	d.106.1 — SCP-like
家族 Family family	d.106.1.4 — EF1021 C-terminal domain-like

结构域编号 domain_id	d2hv2a2
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.108 — Acyl-CoA N-acyltransferases (Nat)
超家族 Superfamily superfamily	d.108.1 — Acyl-CoA N-acyltransferases (Nat)
家族 Family family	d.108.1.10 — EF1021-like

结构域编号 domain_id	d2hv2b1
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.106 — SCP-like
超家族 Superfamily superfamily	d.106.1 — SCP-like
家族 Family family	d.106.1.4 — EF1021 C-terminal domain-like

结构域编号 domain_id	d2hv2b2
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.108 — Acyl-CoA N-acyltransferases (Nat)
超家族 Superfamily superfamily	d.108.1 — Acyl-CoA N-acyltransferases (Nat)
家族 Family family	d.108.1.10 — EF1021-like

结构域编号 domain_id	d2hv2c1
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.106 — SCP-like
超家族 Superfamily superfamily	d.106.1 — SCP-like
家族 Family family	d.106.1.4 — EF1021 C-terminal domain-like

结构域编号 domain_id	d2hv2c2
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.108 — Acyl-CoA N-acyltransferases (Nat)
超家族 Superfamily superfamily	d.108.1 — Acyl-CoA N-acyltransferases (Nat)
家族 Family family	d.108.1.10 — EF1021-like

结构域编号 domain_id	d2hv2d1
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.106 — SCP-like
超家族 Superfamily superfamily	d.106.1 — SCP-like
家族 Family family	d.106.1.4 — EF1021 C-terminal domain-like

结构域编号 domain_id	d2hv2d2
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.108 — Acyl-CoA N-acyltransferases (Nat)
超家族 Superfamily superfamily	d.108.1 — Acyl-CoA N-acyltransferases (Nat)
家族 Family family	d.108.1.10 — EF1021-like

结构域编号 domain_id	d2hv2e1
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.106 — SCP-like
超家族 Superfamily superfamily	d.106.1 — SCP-like
家族 Family family	d.106.1.4 — EF1021 C-terminal domain-like

结构域编号 domain_id	d2hv2e2
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.108 — Acyl-CoA N-acyltransferases (Nat)
超家族 Superfamily superfamily	d.108.1 — Acyl-CoA N-acyltransferases (Nat)
家族 Family family	d.108.1.10 — EF1021-like

结构域编号 domain_id	d2hv2f1
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.106 — SCP-like
超家族 Superfamily superfamily	d.106.1 — SCP-like
家族 Family family	d.106.1.4 — EF1021 C-terminal domain-like

结构域编号 domain_id	d2hv2f2
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.108 — Acyl-CoA N-acyltransferases (Nat)
超家族 Superfamily superfamily	d.108.1 — Acyl-CoA N-acyltransferases (Nat)
家族 Family family	d.108.1.10 — EF1021-like

CATH v4.4 (18 domains)

结构域编号 domain_id	2hv2A01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	630 — Aminopeptidase
同源超家族 H-superfamily homologous superfamily	30 — Gcn5-related N-acetyltransferase (GNAT)

结构域编号 domain_id	2hv2A02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	1050 — Nonspecific Lipid-transfer Protein; Chain A
同源超家族 H-superfamily homologous superfamily	10 — SCP2 sterol-binding domain

结构域编号 domain_id	2hv2A03
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	630 — Aminopeptidase
同源超家族 H-superfamily homologous superfamily	30 — Gcn5-related N-acetyltransferase (GNAT)

结构域编号 domain_id	2hv2B01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	630 — Aminopeptidase
同源超家族 H-superfamily homologous superfamily	30 — Gcn5-related N-acetyltransferase (GNAT)

结构域编号 domain_id	2hv2B02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	1050 — Nonspecific Lipid-transfer Protein; Chain A
同源超家族 H-superfamily homologous superfamily	10 — SCP2 sterol-binding domain

结构域编号 domain_id	2hv2B03
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	630 — Aminopeptidase
同源超家族 H-superfamily homologous superfamily	30 — Gcn5-related N-acetyltransferase (GNAT)

结构域编号 domain_id	2hv2C01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	630 — Aminopeptidase
同源超家族 H-superfamily homologous superfamily	30 — Gcn5-related N-acetyltransferase (GNAT)

结构域编号 domain_id	2hv2C02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	1050 — Nonspecific Lipid-transfer Protein; Chain A
同源超家族 H-superfamily homologous superfamily	10 — SCP2 sterol-binding domain

结构域编号 domain_id	2hv2C03
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	630 — Aminopeptidase
同源超家族 H-superfamily homologous superfamily	30 — Gcn5-related N-acetyltransferase (GNAT)

结构域编号 domain_id	2hv2D01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	630 — Aminopeptidase
同源超家族 H-superfamily homologous superfamily	30 — Gcn5-related N-acetyltransferase (GNAT)

结构域编号 domain_id	2hv2D02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	1050 — Nonspecific Lipid-transfer Protein; Chain A
同源超家族 H-superfamily homologous superfamily	10 — SCP2 sterol-binding domain

结构域编号 domain_id	2hv2D03
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	630 — Aminopeptidase
同源超家族 H-superfamily homologous superfamily	30 — Gcn5-related N-acetyltransferase (GNAT)

结构域编号 domain_id	2hv2E01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	630 — Aminopeptidase
同源超家族 H-superfamily homologous superfamily	30 — Gcn5-related N-acetyltransferase (GNAT)

结构域编号 domain_id	2hv2E02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	1050 — Nonspecific Lipid-transfer Protein; Chain A
同源超家族 H-superfamily homologous superfamily	10 — SCP2 sterol-binding domain

结构域编号 domain_id	2hv2E03
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	630 — Aminopeptidase
同源超家族 H-superfamily homologous superfamily	30 — Gcn5-related N-acetyltransferase (GNAT)

结构域编号 domain_id	2hv2F01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	630 — Aminopeptidase
同源超家族 H-superfamily homologous superfamily	30 — Gcn5-related N-acetyltransferase (GNAT)

结构域编号 domain_id	2hv2F02
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	1050 — Nonspecific Lipid-transfer Protein; Chain A
同源超家族 H-superfamily homologous superfamily	10 — SCP2 sterol-binding domain

结构域编号 domain_id	2hv2F03
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	630 — Aminopeptidase
同源超家族 H-superfamily homologous superfamily	30 — Gcn5-related N-acetyltransferase (GNAT)

▶

晶胞边长 a length_a	189.626 Å
晶胞边长 b length_b	104.277 Å
晶胞边长 c length_c	152.281 Å
晶胞夹角 α angle_alpha	90.00 °
晶胞夹角 β angle_beta	98.26 °
晶胞夹角 γ angle_gamma	90.00 °
晶胞分子数 Z z_pdb	24

空间群 space_group	C 1 2 1
空间群编号 int_tables_number	5
晶系 crystal_system	—

分辨率 resolution	2.400 Å
最低分辨率 resolution_low	20.000 Å
R 因子 r_factor	0.1875
R_work r_work	0.1850
R_free r_free	0.2335

Crystal Structure of Conserved Protein of Unknown Function from Enterococcus faecalis V583 at 2.4 A Resolution, Probable N-Acyltransferase

1. 蛋白身份与相关结构 Protein Identity & Related Structures

Hypothetical protein

当前结构中的状态

数据库中的同蛋白其他状态

2. 结构基本信息 2. Structure Basics

3. Official assembly/model 理论 SAXS Official SAXS Profiles

2hv2__assembly_1__model_1

2hv2__assembly_1__model_1 | I(q)

2hv2__assembly_1__model_1 | P(r) · Pending

4. 晶体学与实验 4. Crystallography & Experiment

晶胞参数 Unit Cell

对称性 Symmetry

精修参数 Refinement

5. 实体与聚合物信息 Entities & Polymers (4)

实体 1 Entity 1 polymer

聚合物 Polymer

来源 Source

实体 2 Entity 2 non-polymer

实体 3 Entity 3 non-polymer

实体 4 Entity 4 water

6. 折叠分类 (SCOP + CATH) 30 domains

SCOP 2.08 (12 domains)

CATH v4.4 (18 domains)

7. 引用文献 (1)

Crystal Structure of Conserved Protein of Unknown Function from Enterococcus faecalis V583 at 2.4 A Resolution, Probable N-Acyltransferase

1. 蛋白身份与相关结构 Protein Identity & Related Structures

Hypothetical protein

当前结构中的状态

数据库中的同蛋白其他状态

单体

同源二聚体

同源四聚体

其他同源多聚体

异源或核酸复合物

2. 结构基本信息 2. Structure Basics

3. Official assembly/model 理论 SAXS Official SAXS Profiles

2hv2__assembly_1__model_1

2hv2__assembly_1__model_1 | I(q)

2hv2__assembly_1__model_1 | P(r) · Pending

4. 晶体学与实验 4. Crystallography & Experiment

晶胞参数 Unit Cell

对称性 Symmetry

精修参数 Refinement

5. 实体与聚合物信息 Entities & Polymers (4)

实体 1 Entity 1 polymer

聚合物 Polymer

来源 Source

实体 2 Entity 2 non-polymer

实体 3 Entity 3 non-polymer

实体 4 Entity 4 water

6. 折叠分类 (SCOP + CATH) 30 domains

SCOP 2.08 (12 domains)

CATH v4.4 (18 domains)

7. 引用文献 (1)