2ice

CRIg bound to C3c

Method: X-RAY DIFFRACTION
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1. 蛋白身份与相关结构 Protein Identity & Related Structures

Complement C3 beta chain

物种未注明

UniProt P01024

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 其他组合 异源复合物 蛋白 4 其他聚合物 1 V-set and immunoglobulin domain-containing protein 4 × 1 (Q9Y279) 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 1 CALCIUM ION × 1 与蛋白数一致
2 蛋白异源复合物 异源复合物 蛋白 4 V-set and immunoglobulin domain-containing protein 4 × 1 (Q9Y279) CALCIUM ION × 1 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 CO3_HUMAN
Isoform —
PDB实体 1, 2, 3
链与序列区间 作者链 A; PDB构建体 1–642; UniProt 23–664 作者链 D; PDB构建体 1–642; UniProt 23–664 作者链 B; PDB构建体 1–206; UniProt 749–954 作者链 E; PDB构建体 1–206; UniProt 749–954 作者链 C; PDB构建体 1–343; UniProt 1321–1663 作者链 F; PDB构建体 1–343; UniProt 1321–1663

V-set and immunoglobulin domain-containing protein 4

Homo sapiens

UniProt Q9Y279

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 其他组合 异源复合物 蛋白 4 其他聚合物 1 Complement C3 beta chain × 1 (P01024) Complement C3 alpha chain × 1 (P01024) Complement C3 alpha chain × 1 (P01024) 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 1 CALCIUM ION × 1 与蛋白数一致
2 蛋白异源复合物 异源复合物 蛋白 4 Complement C3 beta chain × 1 (P01024) Complement C3 alpha chain × 1 (P01024) Complement C3 alpha chain × 1 (P01024) CALCIUM ION × 1 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 VSIG4_HUMAN
Isoform —
PDB实体 4
链与序列区间 作者链 S; PDB构建体 1–119; UniProt 19–137 作者链 T; PDB构建体 1–119; UniProt 19–137

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中;数据库内部编号、导入时间和 assembly 操作表达式仅用于维护,因此不在读者页面展示。

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2. 结构基本信息 2. Structure Basics

条目编号 entry_id2ice
沉积日期 deposition_date2006-09-12
结构标题 titleCRIg bound to C3c
关键词 keywordsAlternative Pathway, Complement, C3, CRIg, Complement Receptor, Immune System; IMMUNE SYSTEM
实验方法 methodX-RAY DIFFRACTION
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3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

2ice__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

2ice__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 个绘图点;横轴和纵轴均采用对数尺度。

2ice__assembly_1__model_1 | P(r) · Pending

新版 assembly/model P(r) 尚未计算 此处仅保留位置,不展示旧数据 r (Angstrom) P(r)
P(r) 将按相同 assembly/model 分别计算和展示。
Rg(Guinier)40.70 Å
Rg(电子密度)40.41 Å
总 Rg40.60 Å
原子数9874
残基数1240
排除体积176410 ų
最大 q0.500 Å⁻¹
Assembly Model 结构单元 聚集说明 状态 CRYSOL 操作
1 1 2ice__assembly_1__model_1 tetrameric (4) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
2 1 2ice__assembly_2__model_1 tetrameric (4) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
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4. 晶体学与实验 4. Crystallography & Experiment

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5. 实体与聚合物信息 Entities & Polymers (6)

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6. 折叠分类 (SCOP + CATH) 22 domains

CATH v4.4 (22 domains)

结构域编号 domain_id2iceA01
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology40 — Immunoglobulin-like
同源超家族 H-superfamily homologous superfamily1930 — Macroglobulin (MG2) domain
结构域编号 domain_id2iceA02
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology40 — Immunoglobulin-like
同源超家族 H-superfamily homologous superfamily1930 — Macroglobulin (MG2) domain
结构域编号 domain_id2iceA03
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology40 — Immunoglobulin-like
同源超家族 H-superfamily homologous superfamily1940 —
结构域编号 domain_id2iceA04
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology40 — Immunoglobulin-like
同源超家族 H-superfamily homologous superfamily10 — Immunoglobulins
结构域编号 domain_id2iceA05
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology40 — Immunoglobulin-like
同源超家族 H-superfamily homologous superfamily1930 — Macroglobulin (MG2) domain
结构域编号 domain_id2iceA06
类 Class class6 — Special
架构 Architecture architecture20 — Other non-globular
拓扑 Topology topology50 — N-terminal domain of TfIIb
同源超家族 H-superfamily homologous superfamily160 —
结构域编号 domain_id2iceB01
类 Class class2 — Mainly Beta
架构 Architecture architecture20 — Single Sheet
拓扑 Topology topology130 — S-adenosyl-L-methionine-dependent methyltransferases
同源超家族 H-superfamily homologous superfamily20 —
结构域编号 domain_id2iceB02
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology40 — Immunoglobulin-like
同源超家族 H-superfamily homologous superfamily10 — Immunoglobulins
结构域编号 domain_id2iceC01
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology40 — Immunoglobulin-like
同源超家族 H-superfamily homologous superfamily690 — Alpha-macroglobulin, receptor-binding domain
结构域编号 domain_id2iceC02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily120 —
结构域编号 domain_id2iceD01
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology40 — Immunoglobulin-like
同源超家族 H-superfamily homologous superfamily1930 — Macroglobulin (MG2) domain
结构域编号 domain_id2iceD02
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology40 — Immunoglobulin-like
同源超家族 H-superfamily homologous superfamily1930 — Macroglobulin (MG2) domain
结构域编号 domain_id2iceD03
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology40 — Immunoglobulin-like
同源超家族 H-superfamily homologous superfamily1940 —
结构域编号 domain_id2iceD04
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology40 — Immunoglobulin-like
同源超家族 H-superfamily homologous superfamily10 — Immunoglobulins
结构域编号 domain_id2iceD05
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology40 — Immunoglobulin-like
同源超家族 H-superfamily homologous superfamily1930 — Macroglobulin (MG2) domain
结构域编号 domain_id2iceD06
类 Class class6 — Special
架构 Architecture architecture20 — Other non-globular
拓扑 Topology topology50 — N-terminal domain of TfIIb
同源超家族 H-superfamily homologous superfamily160 —
结构域编号 domain_id2iceE01
类 Class class2 — Mainly Beta
架构 Architecture architecture20 — Single Sheet
拓扑 Topology topology130 — S-adenosyl-L-methionine-dependent methyltransferases
同源超家族 H-superfamily homologous superfamily20 —
结构域编号 domain_id2iceE02
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology40 — Immunoglobulin-like
同源超家族 H-superfamily homologous superfamily10 — Immunoglobulins
结构域编号 domain_id2iceF01
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology40 — Immunoglobulin-like
同源超家族 H-superfamily homologous superfamily690 — Alpha-macroglobulin, receptor-binding domain
结构域编号 domain_id2iceF02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily120 —
结构域编号 domain_id2iceS00
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology40 — Immunoglobulin-like
同源超家族 H-superfamily homologous superfamily10 — Immunoglobulins
结构域编号 domain_id2iceT00
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology40 — Immunoglobulin-like
同源超家族 H-superfamily homologous superfamily10 — Immunoglobulins
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7. 引用文献 (1)