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2ihn

Co-crystal of Bacteriophage T4 RNase H with a fork DNA substrate

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Ribonuclease H

Enterobacteria phage T4

UniProt P13319

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Monomer Protein 1 DNA 2 5'-D(*CP*TP*AP*AP*CP*TP*TP*TP*GP*AP*GP*GP*CP*AP*GP*AP*CP*C)-3' × 1 5'-D(*GP*GP*TP*CP*TP*GP*CP*CP*TP*CP*AP*AP*GP*AP*CP*GP*GP*TP*AP*GP*TP*CP*AP*A)-3' × 1 water × 3 Consistent with all polymers

Other States of the Same Protein in the Database

Monomer
1tfr 3h7i 3h8j 3h8s 3h8w

5 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
2ihn

1 assemblies

View Construct and Data Evidence
UniProt name RNH_BPT4
Isoform —
PDB entities 3
Chains and sequence ranges Author chain A； PDBConstruct 1–305； UniProt 1–305

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id2ihn
Deposition date deposition_date2006-09-26
Structure title titleCo-crystal of Bacteriophage T4 RNase H with a fork DNA substrate
Keywords keywords;BPT4 RNase H, protein:DNA complex, 5'-3' exonuclease, Hydrolase (nucleic acid), helix-hairpin-helix motif type 2 (HhH2), fork DNA, HYDROLASE-DNA COMPLEX ;; HYDROLASE/DNA
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

2ihn__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

2ihn__assembly_1__model_1 | I(q)

10-2 10-1 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

2ihn__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）23.29 Å
Rg (electron density)22.11 Å
Total Rg23.05 Å
Atom count3155
Residues333
Excluded volume54356 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 2ihn__assembly_1__model_1 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (4)

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6. Fold Classification (SCOP + CATH) 4 domains

SCOP 2.08 (2 domains)

Domain ID domain_idd2ihna1
Class classa — All alpha proteins
Fold Fold folda.60 — SAM domain-like
Superfamily Superfamily superfamilya.60.7 — 5' to 3' exonuclease, C-terminal subdomain
Family Family familya.60.7.1 — 5' to 3' exonuclease, C-terminal subdomain
Domain ID domain_idd2ihna2
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.120 — PIN domain-like
Superfamily Superfamily superfamilyc.120.1 — PIN domain-like
Family Family familyc.120.1.2 — 5' to 3' exonuclease catalytic domain

CATH v4.4 (2 domains)

Domain ID domain_id2ihnA01
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily1010 — 5'-nuclease
Domain ID domain_id2ihnA02
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology150 — DNA polymerase; domain 1
Homologous superfamily homologous superfamily20 — 5' to 3' exonuclease, C-terminal subdomain
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7. Citations (1)