DENGUE VIRUS 4
| Assembly | 物理组成 | 蛋白状态 | 分子拷贝数 | 共同组分 | 数据核对 |
|---|---|---|---|---|---|
| 1 | 蛋白–RNA | 单体 | 蛋白 1 RNA 1 | 5'-R(*UP*AP*GP*AP*CP*UP*AP*AP*CP*AP*AP*CP*U)-3' × 1 PHOSPHATE ION × 1 water × 2 | 与全部聚合物一致 |
| 2 | 蛋白–RNA | 单体 | 蛋白 1 RNA 1 | 5'-R(*UP*AP*GP*AP*CP*UP*AP*AP*CP*AP*AP*CP*U)-3' × 1 PHOSPHATE ION × 1 GLYCEROL × 1 water × 1 | 与全部聚合物一致 |
| UniProt名称 | POLG_DEN4T |
| Isoform | — |
| PDB实体 | 1 |
| 链与序列区间 | 作者链 A； PDB构建体 5–451； UniProt 1646–2092 作者链 B； PDB构建体 5–451； UniProt 1646–2092 |
页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。
| 条目编号 entry_id | 2jlw |
| 沉积日期 deposition_date | 2008-09-15 |
| 结构标题 title | Dengue virus 4 NS3 helicase in complex with ssRNA2 |
| 关键词 keywords | ;HYDROLASE-RNA COMPLEX, RNA-BINDING, FLAVIVIRUSES, GLYCOPROTEIN, DENGUE VIRUS, TRANSCRIPTION REGULATION, RNA-DIRECTED RNA POLYMERASE, NUCLEOTIDE-BINDING, VIRAL NUCLEOPROTEIN, CLEAVAGE ON PAIR OF BASIC RESIDUES, PROTEASE, HYDROLASE, TRANSFERASE, ATP-BINDING, ENDOPLASMIC RETICULUM, NUCLEOTIDYLTRANSFERASE, PHOSPHOPROTEIN, CAPSID PROTEIN, RNA REPLICATION, SERINE PROTEASE, ENVELOPE PROTEIN, RIBONUCLEOPROTEIN, NS3 HELICASE STRUCTURE, MULTIFUNCTIONAL ENZYME, SSRNA, VIRION, NUCLEUS, MEMBRANE, SECRETED, HELICASE, METAL-BINDING, TRANSMEMBRANE, TRANSCRIPTION ;; HYDROLASE/RNA |
| 实验方法 method | X-RAY DIFFRACTION |
页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。
Assembly 2 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 23.74 Å |
| Rg（电子密度） | 22.77 Å |
| 总 Rg | 23.57 Å |
| 原子数 | 3711 |
| 残基数 | 456 |
| 排除体积 | 65385 ų |
| 最大 q | 0.500 Å⁻¹ |
| 结构域编号 domain_id | d2jlwa1 |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.37 — P-loop containing nucleoside triphosphate hydrolases |
| 超家族 Superfamily superfamily | c.37.1 — P-loop containing nucleoside triphosphate hydrolases |
| 家族 Family family | c.37.1.14 — RNA helicase |
| 结构域编号 domain_id | d2jlwa2 |
| 类 Class class | l — Artifacts |
| 折叠类型 Fold fold | l.1 — Tags |
| 超家族 Superfamily superfamily | l.1.1 — Tags |
| 家族 Family family | l.1.1.1 — Tags |
| 结构域编号 domain_id | d2jlwb1 |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.37 — P-loop containing nucleoside triphosphate hydrolases |
| 超家族 Superfamily superfamily | c.37.1 — P-loop containing nucleoside triphosphate hydrolases |
| 家族 Family family | c.37.1.14 — RNA helicase |
| 结构域编号 domain_id | d2jlwb2 |
| 类 Class class | l — Artifacts |
| 折叠类型 Fold fold | l.1 — Tags |
| 超家族 Superfamily superfamily | l.1.1 — Tags |
| 家族 Family family | l.1.1.1 — Tags |
| 结构域编号 domain_id | 2jlwA01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 300 — P-loop containing nucleotide triphosphate hydrolases |
| 结构域编号 domain_id | 2jlwA02 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 300 — P-loop containing nucleotide triphosphate hydrolases |
| 结构域编号 domain_id | 2jlwB01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 300 — P-loop containing nucleotide triphosphate hydrolases |
| 结构域编号 domain_id | 2jlwB02 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 300 — P-loop containing nucleotide triphosphate hydrolases |