2kbo
Structure, interaction, and real-time monitoring of the enzymatic reaction of wild type APOBEC3G
SAXS 散射曲线 SAXS Profile
P(r) 距离分布 P(r) Distribution
1. 结构基本信息 1. Structure Basics
| 条目编号 entry_id | 2kbo |
| 沉积日期 deposition_date | 2008-12-04 |
| 结构标题 title | Structure, interaction, and real-time monitoring of the enzymatic reaction of wild type APOBEC3G |
| 关键词 keywords | ;Cytidine deaminase, HIV, APOBEC3G, Alternative splicing, Antiviral defense, Cytoplasm, Host-virus interaction, Hydrolase, Metal-binding, Nucleus, Polymorphism, Ubl conjugation, Zinc ;; HYDROLASE |
| 实验方法 method | SOLUTION NMR |
2. SAXS 参数 (CRYSOL 理论计算) 2. SAXS Parameters (CRYSOL)
| 回转半径 Rg (Guinier) rg_guinier | 18.48 Å |
| 回转半径 Rg (电子) rg_electron | 17.93 Å |
| 零角强度 I(0) i0 | 810652000.00 |
| 分子量 molecular_weight | 229560.0 kDa |
| 排除体积 excluded_volume | 282080 ų |
| 包络体积 envelope_volume | 53383 ų |
| 水化壳体积 shell_volume | 22241 ų |
| 包络直径 envelope_diameter | 69.6 Å |
| 壳层 Rg shell_rg | 26.75 Å |
| 包络 Rg envelope_rg | 20.12 Å |
| 形状 Rg shape_rg | 17.97 Å |
| 总 Rg total_rg | 18.02 Å |
| 总原子数 total_atoms | 31280 |
| 残基数 n_residues | 1940 |
| 球谐函数阶数 n_harmonics | 20 |
| q 范围 q_range | — – 0.5000 Å−1 |
| 数据点数 n_points | 101 |
| 壳层类型 shell_type | directional |
| 溶剂电子密度 solvent_density | 0.3340 e/ų |
| 壳层衬度 contrast_shell | 0.0300 e/ų |
| CRYSOL 版本 crysol_version | 4.1.3 |
3. P(r) 距离分布 (GNOM 反演) 3. P(r) Analysis (GNOM)
| 最大尺寸 Dmax dmax | 63.7 Å |
| Rg (实空间) rg_real | 18.40 Å |
| Rg 误差 (实空间) rg_real_error | 0.56 Å |
| I(0) (实空间) i0_real | 8.1070e+08 |
| I(0) 误差 (实空间) i0_real_error | 1.0420e+07 |
| Rg (倒空间) rg_reciprocal | 18.41 Å |
| I(0) (倒空间) i0_reciprocal | 810700000.0000 |
| 解质量估计 total_estimate | 0.7869 |
| 解质量评级 solution_quality | GOOD a GOOD solution |
| P(r) 峰数 n_peaks | 3 |
| 主峰位置 r_peak_primary | 24.4 Å |
| 偏度 Skewness skewness | 0.170 |
| 峰度 Kurtosis kurtosis | -0.388 |
| 角度范围 angular_range | — – 0.4300 Å−1 |
| 当前正则化参数 α current_alpha | 0.0000 |
| 最高正则化参数 α highest_alpha | 1214000.0000 |
| 实空间数据点数 n_real_points | 74 |
| GNOM 版本 gnom_version | 4.1.3 |
| 质量判据 quality_criteria | AN1: 0.000; Oscil: 0.747; Stabil: 0.995; Sysdev: 1.000; Positv: 1.000; Valcen: 0.997; Smooth: 0.000 |
4. 晶体学与实验 4. Crystallography & Experiment
5. 实体与聚合体信息 (2)
6. 折叠分类 (SCOP + CATH) 2 domains
SCOP 2.08 (2 domains)
| 结构域编号 domain_id | d2kboa1 |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.97 — Cytidine deaminase-like |
| 超家族 Superfamily superfamily | c.97.1 — Cytidine deaminase-like |
| 家族 Family family | c.97.1.6 — apolipoprotein B messenger RNA-editing enzyme catalytic (APOBEC) cytidine deaminase domains |
| 结构域编号 domain_id | d2kboa2 |
| 类 Class class | l — Artifacts |
| 折叠类型 Fold fold | l.1 — Tags |
| 超家族 Superfamily superfamily | l.1.1 — Tags |
| 家族 Family family | l.1.1.1 — Tags |