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2ly0

Solution NMR structure of the influenza A virus S31N mutant (19-49) in presence of drug M2WJ332

Method: SOLUTION NMR
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Membrane ion channel M2

OrganismNot specified

UniProt Q6XT21

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 4 (3S,5S,7S)-N-{[5-(thiophen-2-yl)-1,2-oxazol-3-yl]methyl}tricyclo[3.3.1.1~3,7~]decan-1-aminium × 1 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer
2ly0

1 assemblies

Other homooligomers

None

Heteromeric or nucleic-acid complex

None

View Construct and Data Evidence
UniProt name Q6XT21_9INFA
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–31； UniProt 19–49 Author chain B； PDBConstruct 1–31； UniProt 19–49 Author chain C； PDBConstruct 1–31； UniProt 19–49 Author chain D； PDBConstruct 1–31； UniProt 19–49

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id2ly0
Deposition date deposition_date2012-09-10
Structure title titleSolution NMR structure of the influenza A virus S31N mutant (19-49) in presence of drug M2WJ332
Keywords keywordsinfluenza A virus, M2 channel, S31N inhibitor, VIRAL PROTEIN; VIRAL PROTEIN
Experimental Method methodSOLUTION NMR
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

2ly0__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

2ly0__assembly_1__model_1 | I(q)

10-2 10-1 104 105 106 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

2ly0__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）17.43 Å
Rg (electron density)16.33 Å
Total Rg17.51 Å
Atom count2081
Residues124
Excluded volume18671 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 2ly0__assembly_1__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 2 2ly0__assembly_1__model_2 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 3 2ly0__assembly_1__model_3 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 4 2ly0__assembly_1__model_4 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 5 2ly0__assembly_1__model_5 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 6 2ly0__assembly_1__model_6 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 7 2ly0__assembly_1__model_7 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 8 2ly0__assembly_1__model_8 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 9 2ly0__assembly_1__model_9 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 10 2ly0__assembly_1__model_10 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 11 2ly0__assembly_1__model_11 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 12 2ly0__assembly_1__model_12 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 13 2ly0__assembly_1__model_13 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 14 2ly0__assembly_1__model_14 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 15 2ly0__assembly_1__model_15 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 16 2ly0__assembly_1__model_16 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 17 2ly0__assembly_1__model_17 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 18 2ly0__assembly_1__model_18 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 19 2ly0__assembly_1__model_19 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 20 2ly0__assembly_1__model_20 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (2)

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7. Citations (1)