Homo sapiens
| Assembly | Physical composition | Protein state | Molecular copy count | Associated components | Data consistency |
|---|---|---|---|---|---|
| 1 | Protein heterocomplex | Heteromer | Protein 2 | MCo-PMI × 1 | Consistent with protein count |
| UniProt name | MDM2_HUMAN |
| Isoform | — |
| PDB entities | 2 |
| Chains and sequence ranges | Author chain B； PDBConstruct 21–129； UniProt 17–125 |
The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.
| Entry ID entry_id | 2m86 |
| Deposition date deposition_date | 2013-05-07 |
| Structure title title | Solution structure of Hdm2 with engineered cyclotide |
| Keywords keywords | Hdm2 oncoprotein, MCoTI-I cyclotide, p53 tumor suppressor, PROTEIN BINDING-SIGNALING PROTEIN complex; PROTEIN BINDING/SIGNALING PROTEIN |
| Experimental Method method | SOLUTION NMR |
This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.
Assembly 1 · Model 9 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 16.46 Å |
| Rg (electron density) | 15.13 Å |
| Total Rg | 16.46 Å |
| Atom count | 2126 |
| Residues | 134 |
| Excluded volume | 19011 ų |
| Maximum q | 0.500 Å⁻¹ |
| Assembly | Model | Structure unit | Oligomeric description | Status | CRYSOL | Actions |
|---|---|---|---|---|---|---|
| 1 | 1 | 2m86__assembly_1__model_1 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 2 | 2m86__assembly_1__model_2 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 3 | 2m86__assembly_1__model_3 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 4 | 2m86__assembly_1__model_4 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 5 | 2m86__assembly_1__model_5 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 6 | 2m86__assembly_1__model_6 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 7 | 2m86__assembly_1__model_7 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 8 | 2m86__assembly_1__model_8 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 9 | 2m86__assembly_1__model_9 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| 1 | 10 | 2m86__assembly_1__model_10 |
dimeric （2） | Success | 4.1.3-1-20251215 (887e7ef) | View Download |
| Domain ID domain_id | 2m86A00 |
| Class class | 4 — Few Secondary Structures |
| Architecture architecture | 10 — Irregular |
| Topology topology | 75 — R-elafin |
| Homologous superfamily homologous superfamily | 20 — |
| Domain ID domain_id | 2m86B00 |
| Class class | 1 — Mainly Alpha |
| Architecture architecture | 10 — Orthogonal Bundle |
| Topology topology | 245 — MDM2 |
| Homologous superfamily homologous superfamily | 10 — SWIB/MDM2 domain |