1ycr

MDM2 BOUND TO THE TRANSACTIVATION DOMAIN OF P53

Method: X-RAY DIFFRACTION
▼

1. Protein Identity and Related Structures Protein Identity & Related Structures

MDM2

Homo sapiens

UniProt Q00987

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 2 P53 × 1 (P04637) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name MDM2_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 1–109; UniProt 17–125

P53

OrganismNot specified

UniProt P04637

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 2 MDM2 × 1 (Q00987) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name P53_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B; PDBConstruct 1–15; UniProt 15–29

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

▼

2. Structure Basics 2. Structure Basics

Entry ID entry_id1ycr
Deposition date deposition_date1996-09-30
Structure title titleMDM2 BOUND TO THE TRANSACTIVATION DOMAIN OF P53
Keywords keywords;ANTI-ONCOGENE, DNA-BINDING, TRANSCRIPTION REGULATION, NUCLEAR PROTEIN, COMPLEX (ONCOGENE PROTEIN-PEPTIDE), PHOSPHORYLATION, ACTIVATOR, COMPLEX (ONCOGENE PROTEIN-PEPTIDE) complex ;; COMPLEX (ONCOGENE PROTEIN/PEPTIDE)
Experimental Method methodX-RAY DIFFRACTION
▼

3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

1ycr__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

1ycr__assembly_1__model_1 | I(q)

10-2 10-1 105 106 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

1ycr__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)14.22 Å
Rg (electron density)12.73 Å
Total Rg14.15 Å
Atom count818
Residues98
Excluded volume14940 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 1ycr__assembly_1__model_1 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
▶

4. Crystallography and Experiment 4. Crystallography & Experiment

▶

5. Entities and Polymers Entities & Polymers (2)

▼

6. Fold Classification (SCOP + CATH) 2 domains

SCOP 2.08 (1 domains)

Domain ID domain_idd1ycra_
Class classa — All alpha proteins
Fold Fold folda.42 — SWIB/MDM2 domain
Superfamily Superfamily superfamilya.42.1 — SWIB/MDM2 domain
Family Family familya.42.1.1 — SWIB/MDM2 domain

CATH v4.4 (1 domains)

Domain ID domain_id1ycrA00
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology245 — MDM2
Homologous superfamily homologous superfamily10 — SWIB/MDM2 domain
▶

7. Citations (1)