HOMO SAPIENS
| Assembly | Physical composition | Protein state | Molecular copy count | Associated components | Data consistency |
|---|---|---|---|---|---|
| 1 | Protein monomer | Monomer | Protein 1 | ZINC ION × 1 water × 1 | Consistent with protein count |
| UniProt name | P53_HUMAN |
| Isoform | — |
| PDB entities | 1 |
| Chains and sequence ranges | Author chain A； PDBConstruct 1–219； UniProt 94–312 |
The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.
| Entry ID entry_id | 2bip |
| Deposition date deposition_date | 2005-01-25 |
| Structure title title | human p53 core domain mutant M133L-H168R-V203A-N239Y-R249S-N268D |
| Keywords keywords | ;ACTIVATOR, ANTI-ONCOGENE, APOPTOSIS, DISEASE MUTATION, DNA-BINDING, DNA-BINDING PROTEIN, LI-FRAUMENI SYNDROME, NUCLEAR PROTEIN, P53 DNA-BINDING DOMAIN, PHOSPHORYLATION, POLYMORPHISM, SECOND-SITE SUPPRESSOR MUTATION, SUPERSTABLE MUTANT, TRANSCRIPTION REGULATION, TUMOR SUPPRESSOR, TRANSFERASE, ACETYLATION, GLYCOPROTEIN METAL-BINDING, ZINC, DNA BINDING PROTEIN ;; DNA BINDING PROTEIN |
| Experimental Method method | X-RAY DIFFRACTION |
This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 17.39 Å |
| Rg (electron density) | 16.05 Å |
| Total Rg | 17.10 Å |
| Atom count | 1466 |
| Residues | 185 |
| Excluded volume | 25814 ų |
| Maximum q | 0.500 Å⁻¹ |
| Domain ID domain_id | d2bipa_ |
| Class class | b — All beta proteins |
| Fold Fold fold | b.2 — Common fold of diphtheria toxin/transcription factors/cytochrome f |
| Superfamily Superfamily superfamily | b.2.5 — p53-like transcription factors |
| Family Family family | b.2.5.2 — p53 DNA-binding domain-like |
| Domain ID domain_id | 2bipA00 |
| Class class | 2 — Mainly Beta |
| Architecture architecture | 60 — Sandwich |
| Topology topology | 40 — Immunoglobulin-like |
| Homologous superfamily homologous superfamily | 720 — |