Homo sapiens
| Assembly | Physical composition | Protein state | Molecular copy count | Associated components | Data consistency |
|---|---|---|---|---|---|
| 1 | Protein monomer | Monomer | Protein 1 | CHLORIDE ION × 1 water × 1 | Consistent with protein count |
| UniProt name | ITCH_HUMAN |
| Isoform | — |
| PDB entities | 1 |
| Chains and sequence ranges | Author chain A； PDBConstruct 19–173； UniProt 1–155 |
The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.
| Entry ID entry_id | 2nq3 |
| Deposition date deposition_date | 2006-10-30 |
| Structure title title | Crystal structure of the C2 Domain of Human Itchy Homolog E3 Ubiquitin Protein Ligase |
| Keywords keywords | C2 DOMAIN, LIGASE, UBL CONJUGATION PATHWAY, STRUCTURAL GENOMICS CONSORTIUM, SGC; LIGASE |
| Experimental Method method | X-RAY DIFFRACTION |
This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 16.55 Å |
| Rg (electron density) | 15.53 Å |
| Total Rg | 16.62 Å |
| Atom count | 1015 |
| Residues | 131 |
| Excluded volume | 18292 ų |
| Maximum q | 0.500 Å⁻¹ |
| Domain ID domain_id | d2nq3a1 |
| Class class | b — All beta proteins |
| Fold Fold fold | b.7 — C2 domain-like |
| Superfamily Superfamily superfamily | b.7.1 — C2 domain (Calcium/lipid-binding domain, CaLB) |
| Family Family family | b.7.1.1 — PLC-like (P variant) |
| Domain ID domain_id | 2nq3A00 |
| Class class | 2 — Mainly Beta |
| Architecture architecture | 60 — Sandwich |
| Topology topology | 40 — Immunoglobulin-like |
| Homologous superfamily homologous superfamily | 150 — C2 domain |