;Crystal structure of human factor XA complexed with 3-chloro-N-(4-chloro-2-{[(5-chloropyridin-2-yl)amino]carbonyl}-6-methoxyphenyl)-4-[(1-methyl-1H-imidazol-2-yl)methyl]thiophene-2-carboxamide {Pfizer 320663}
;
Not Published
PRIMARY
Substituted thiophene-anthranilamides as potent inhibitors of human factor Xa
Bioorg.Med.Chem. (2007)
Structure-activity relationships of substituted benzothiophene-anthranilamide factor Xa inhibitors
Bioorg.Med.Chem.Lett. (2003)
Crystal Structures of Two Potent Nonamidine Inhibitors Bound to Factor Xa
Biochemistry (2002)
Preparation, Characterization and the Crystal Structure of the Inhibitor ZK-807834 (Ci-1031) Complexed with Factor Xa
Biochemistry (2000)
Crystal Structures of Human Factor Xa Complexed with Potent Inhibitors
J.Med.Chem. (2000)
;Discovery of N-[2-[5-[Amino(Imino)Methyl]-2-Hydroxyphenoxy]-3,5-Difluoro- 6-[3-(4,5-Dihydro-1-Methyl-1H-Imidazol-2-Yl)Phenoxy]Pyridin-4-Yl]-N-Methylglycine (Zk-807834): A Potent, Selective, and Orally Active Inhibitor of the Blood Coagulation Enzyme Factor Xa
;
J.Med.Chem. (1998)
Discovery of Highly Potent and Orally Available Thiophene-Anthranilamide-Based Factor Xa Inhibitors
TO BE PUBLISHED