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2r7c

Crystallographic and biochemical analysis of rotavirus NSP2 with nucleotides reveals an NDP kinase like activity

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Non-structural RNA-binding protein 35

Simian 11 rotavirus (serotype 3 / strain SA11-Ramig)

UniProt Q03243

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 8 PHOSPHATE ION × 8 water × 8 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
4g0j 4g0j 4g0j 4g0j 4g0j 4g0j 4g0j 4g0j 4g0j 4g0j

10 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers
1l9v 2r7c 2r7j 2r7p 2r8f 9ogq

6 assemblies

Heteromeric or nucleic-acid complex
4g0a

1 assemblies

View Construct and Data Evidence
UniProt name VN35_ROTSR
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–317； UniProt 1–317

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id2r7c
Deposition date deposition_date2007-09-07
Structure title titleCrystallographic and biochemical analysis of rotavirus NSP2 with nucleotides reveals an NDP kinase like activity
Keywords keywordsRotavirus, NDP Kinase, non structural protein, NTPase, RNA binding protein, RNA-binding; RNA BINDING PROTEIN
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

2r7c__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

2r7c__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

2r7c__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）46.62 Å
Rg (electron density)45.65 Å
Total Rg46.11 Å
Atom count20160
Residues2456
Excluded volume361800 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 2r7c__assembly_1__model_1 octameric （8） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

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6. Fold Classification (SCOP + CATH) 4 domains

SCOP 2.08 (2 domains)

Domain ID domain_idd2r7ca1
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.13 — HIT-like
Superfamily Superfamily superfamilyd.13.2 — Rotavirus NSP2 fragment, C-terminal domain
Family Family familyd.13.2.1 — Rotavirus NSP2 fragment, C-terminal domain
Domain ID domain_idd2r7ca2
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.216 — Rotavirus NSP2 fragment, N-terminal domain
Superfamily Superfamily superfamilyd.216.1 — Rotavirus NSP2 fragment, N-terminal domain
Family Family familyd.216.1.1 — Rotavirus NSP2 fragment, N-terminal domain

CATH v4.4 (2 domains)

Domain ID domain_id2r7cA01
Class class3 — Alpha Beta
Architecture architecture90 — Alpha-Beta Complex
Topology topology1400 — Rotavirus NSP2 fragment, N-terminal domain
Homologous superfamily homologous superfamily10 — Rotavirus NSP2 fragment, N-terminal domain
Domain ID domain_id2r7cA02
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology428 — HIT family, subunit A
Homologous superfamily homologous superfamily20 — Rotavirus NSP2 fragment, C-terminal domain
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7. Citations (2)