← Back to search
2uyx

metallo-beta-lactamase (1BC2) single point mutant D120S

Method: X-RAY DIFFRACTION
▼

1. Protein Identity and Related Structures Protein Identity & Related Structures

BETA-LACTAMASE II

BACILLUS CEREUS

UniProt P04190

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein monomer Monomer Protein 1 GLYCEROL × 4 ZINC ION × 2 water × 1 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1bmc 1bvt 1dxk 1mqo 2bc2 2bc2 2bfk 2bfk 2bfl 2bfl 2bfz 2bfz

60 assemblies; showing the first 12

Homodimer
1bc2 2bc2 2nze

3 assemblies

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex

None

View Construct and Data Evidence
UniProt name BLA2_BACCE
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–20； UniProt 30–49 Author chain A； PDBConstruct 21–38； UniProt 50–67 Author chain A； PDBConstruct 39–73； UniProt 68–102 Author chain A； PDBConstruct 74–79； UniProt 103–108 Author chain A； PDBConstruct 80–102； UniProt 109–131 Author chain A； PDBConstruct 103–120； UniProt 132–149 Author chain A； PDBConstruct 121–159； UniProt 150–188 Author chain A； PDBConstruct 160–162； UniProt 189–191 Author chain A； PDBConstruct 163–213； UniProt 192–242 Author chain A； PDBConstruct 214–228； UniProt 243–257

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

▼

2. Structure Basics 2. Structure Basics

Entry ID entry_id2uyx
Deposition date deposition_date2007-04-20
Structure title titlemetallo-beta-lactamase (1BC2) single point mutant D120S
Keywords keywordsHYDROLASE, PENICILLINASE, METAL-BINDING, ANTIBIOTIC RESISTANCE, METALLO BETA- LACTAMASE; HYDROLASE
Experimental Method methodX-RAY DIFFRACTION
▼

3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

2uyx__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

2uyx__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

2uyx__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）17.29 Å
Rg (electron density)16.12 Å
Total Rg17.27 Å
Atom count1701
Residues218
Excluded volume30575 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 2uyx__assembly_1__model_1 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
▶

4. Crystallography and Experiment 4. Crystallography & Experiment

▶

5. Entities and Polymers Entities & Polymers (4)

▼

6. Fold Classification (SCOP + CATH) 2 domains

SCOP 2.08 (1 domains)

Domain ID domain_idd2uyxa_
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.157 — Metallo-hydrolase/oxidoreductase
Superfamily Superfamily superfamilyd.157.1 — Metallo-hydrolase/oxidoreductase
Family Family familyd.157.1.1 — Zn metallo-beta-lactamase

CATH v4.4 (1 domains)

Domain ID domain_id2uyxA00
Class class3 — Alpha Beta
Architecture architecture60 — 4-Layer Sandwich
Topology topology15 — Metallo-beta-lactamase; Chain A
Homologous superfamily homologous superfamily10 — Ribonuclease Z/Hydroxyacylglutathione hydrolase-like
▶

7. Citations (1)