2ww9

Cryo-EM structure of the active yeast Ssh1 complex bound to the yeast 80S ribosome

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

SEC SIXTY-ONE PROTEIN HOMOLOG

OrganismNot specified

UniProt P38353

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 11 RNA 4 PROTEIN TRANSPORT PROTEIN SSS1 × 1 (P35179) PROTEIN TRANSPORT PROTEIN SEB2 × 1 (P52871) 25S RRNA × 1 25S RRNA × 1 25S RRNA × 1 25S RRNA × 1 60S RIBOSOMAL PROTEIN L4-B × 1 (P49626) 60S RIBOSOMAL PROTEIN L17-A × 1 (P05740) 60S RIBOSOMAL PROTEIN L19 × 1 (P05735) 60S RIBOSOMAL PROTEIN L25 × 1 (P04456) 60S RIBOSOMAL PROTEIN L26-A × 1 (P05743) 60S RIBOSOMAL PROTEIN L31-A × 1 (P0C2H8) 60S RIBOSOMAL PROTEIN L35 × 1 (P39741) 60S RIBOSOMAL PROTEIN L39 × 1 (P04650) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SSH1_YEAST
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 1–490; UniProt 1–490

PROTEIN TRANSPORT PROTEIN SSS1

OrganismNot specified

UniProt P35179

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 11 RNA 4 SEC SIXTY-ONE PROTEIN HOMOLOG × 1 (P38353) PROTEIN TRANSPORT PROTEIN SEB2 × 1 (P52871) 25S RRNA × 1 25S RRNA × 1 25S RRNA × 1 25S RRNA × 1 60S RIBOSOMAL PROTEIN L4-B × 1 (P49626) 60S RIBOSOMAL PROTEIN L17-A × 1 (P05740) 60S RIBOSOMAL PROTEIN L19 × 1 (P05735) 60S RIBOSOMAL PROTEIN L25 × 1 (P04456) 60S RIBOSOMAL PROTEIN L26-A × 1 (P05743) 60S RIBOSOMAL PROTEIN L31-A × 1 (P0C2H8) 60S RIBOSOMAL PROTEIN L35 × 1 (P39741) 60S RIBOSOMAL PROTEIN L39 × 1 (P04650) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SC61G_YEAST
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B; PDBConstruct 1–80; UniProt 1–80

PROTEIN TRANSPORT PROTEIN SEB2

OrganismNot specified

UniProt P52871

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 11 RNA 4 SEC SIXTY-ONE PROTEIN HOMOLOG × 1 (P38353) PROTEIN TRANSPORT PROTEIN SSS1 × 1 (P35179) 25S RRNA × 1 25S RRNA × 1 25S RRNA × 1 25S RRNA × 1 60S RIBOSOMAL PROTEIN L4-B × 1 (P49626) 60S RIBOSOMAL PROTEIN L17-A × 1 (P05740) 60S RIBOSOMAL PROTEIN L19 × 1 (P05735) 60S RIBOSOMAL PROTEIN L25 × 1 (P04456) 60S RIBOSOMAL PROTEIN L26-A × 1 (P05743) 60S RIBOSOMAL PROTEIN L31-A × 1 (P0C2H8) 60S RIBOSOMAL PROTEIN L35 × 1 (P39741) 60S RIBOSOMAL PROTEIN L39 × 1 (P04650) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SC6B2_YEAST
Isoform —
PDB entities 3
Chains and sequence ranges Author chain C; PDBConstruct 1–87; UniProt 1–87

60S RIBOSOMAL PROTEIN L4-B

OrganismNot specified

UniProt P49626

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 11 RNA 4 SEC SIXTY-ONE PROTEIN HOMOLOG × 1 (P38353) PROTEIN TRANSPORT PROTEIN SSS1 × 1 (P35179) PROTEIN TRANSPORT PROTEIN SEB2 × 1 (P52871) 25S RRNA × 1 25S RRNA × 1 25S RRNA × 1 25S RRNA × 1 60S RIBOSOMAL PROTEIN L17-A × 1 (P05740) 60S RIBOSOMAL PROTEIN L19 × 1 (P05735) 60S RIBOSOMAL PROTEIN L25 × 1 (P04456) 60S RIBOSOMAL PROTEIN L26-A × 1 (P05743) 60S RIBOSOMAL PROTEIN L31-A × 1 (P0C2H8) 60S RIBOSOMAL PROTEIN L35 × 1 (P39741) 60S RIBOSOMAL PROTEIN L39 × 1 (P04650) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RL4B_YEAST
Isoform —
PDB entities 8
Chains and sequence ranges Author chain H; PDBConstruct 1–362; UniProt 1–362

60S RIBOSOMAL PROTEIN L17-A

OrganismNot specified

UniProt P05740

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 11 RNA 4 SEC SIXTY-ONE PROTEIN HOMOLOG × 1 (P38353) PROTEIN TRANSPORT PROTEIN SSS1 × 1 (P35179) PROTEIN TRANSPORT PROTEIN SEB2 × 1 (P52871) 25S RRNA × 1 25S RRNA × 1 25S RRNA × 1 25S RRNA × 1 60S RIBOSOMAL PROTEIN L4-B × 1 (P49626) 60S RIBOSOMAL PROTEIN L19 × 1 (P05735) 60S RIBOSOMAL PROTEIN L25 × 1 (P04456) 60S RIBOSOMAL PROTEIN L26-A × 1 (P05743) 60S RIBOSOMAL PROTEIN L31-A × 1 (P0C2H8) 60S RIBOSOMAL PROTEIN L35 × 1 (P39741) 60S RIBOSOMAL PROTEIN L39 × 1 (P04650) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RL17A_YEAST
Isoform —
PDB entities 9
Chains and sequence ranges Author chain I; PDBConstruct 1–184; UniProt 1–184

60S RIBOSOMAL PROTEIN L19

OrganismNot specified

UniProt P05735

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 11 RNA 4 SEC SIXTY-ONE PROTEIN HOMOLOG × 1 (P38353) PROTEIN TRANSPORT PROTEIN SSS1 × 1 (P35179) PROTEIN TRANSPORT PROTEIN SEB2 × 1 (P52871) 25S RRNA × 1 25S RRNA × 1 25S RRNA × 1 25S RRNA × 1 60S RIBOSOMAL PROTEIN L4-B × 1 (P49626) 60S RIBOSOMAL PROTEIN L17-A × 1 (P05740) 60S RIBOSOMAL PROTEIN L25 × 1 (P04456) 60S RIBOSOMAL PROTEIN L26-A × 1 (P05743) 60S RIBOSOMAL PROTEIN L31-A × 1 (P0C2H8) 60S RIBOSOMAL PROTEIN L35 × 1 (P39741) 60S RIBOSOMAL PROTEIN L39 × 1 (P04650) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RL19_YEAST
Isoform —
PDB entities 10
Chains and sequence ranges Author chain J; PDBConstruct 1–189; UniProt 1–189

60S RIBOSOMAL PROTEIN L25

OrganismNot specified

UniProt P04456

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 11 RNA 4 SEC SIXTY-ONE PROTEIN HOMOLOG × 1 (P38353) PROTEIN TRANSPORT PROTEIN SSS1 × 1 (P35179) PROTEIN TRANSPORT PROTEIN SEB2 × 1 (P52871) 25S RRNA × 1 25S RRNA × 1 25S RRNA × 1 25S RRNA × 1 60S RIBOSOMAL PROTEIN L4-B × 1 (P49626) 60S RIBOSOMAL PROTEIN L17-A × 1 (P05740) 60S RIBOSOMAL PROTEIN L19 × 1 (P05735) 60S RIBOSOMAL PROTEIN L26-A × 1 (P05743) 60S RIBOSOMAL PROTEIN L31-A × 1 (P0C2H8) 60S RIBOSOMAL PROTEIN L35 × 1 (P39741) 60S RIBOSOMAL PROTEIN L39 × 1 (P04650) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RL25_YEAST
Isoform —
PDB entities 11
Chains and sequence ranges Author chain K; PDBConstruct 1–142; UniProt 1–142

60S RIBOSOMAL PROTEIN L26-A

OrganismNot specified

UniProt P05743

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 11 RNA 4 SEC SIXTY-ONE PROTEIN HOMOLOG × 1 (P38353) PROTEIN TRANSPORT PROTEIN SSS1 × 1 (P35179) PROTEIN TRANSPORT PROTEIN SEB2 × 1 (P52871) 25S RRNA × 1 25S RRNA × 1 25S RRNA × 1 25S RRNA × 1 60S RIBOSOMAL PROTEIN L4-B × 1 (P49626) 60S RIBOSOMAL PROTEIN L17-A × 1 (P05740) 60S RIBOSOMAL PROTEIN L19 × 1 (P05735) 60S RIBOSOMAL PROTEIN L25 × 1 (P04456) 60S RIBOSOMAL PROTEIN L31-A × 1 (P0C2H8) 60S RIBOSOMAL PROTEIN L35 × 1 (P39741) 60S RIBOSOMAL PROTEIN L39 × 1 (P04650) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RL26A_YEAST
Isoform —
PDB entities 12
Chains and sequence ranges Author chain L; PDBConstruct 1–127; UniProt 1–127

60S RIBOSOMAL PROTEIN L31-A

OrganismNot specified

UniProt P0C2H8

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 11 RNA 4 SEC SIXTY-ONE PROTEIN HOMOLOG × 1 (P38353) PROTEIN TRANSPORT PROTEIN SSS1 × 1 (P35179) PROTEIN TRANSPORT PROTEIN SEB2 × 1 (P52871) 25S RRNA × 1 25S RRNA × 1 25S RRNA × 1 25S RRNA × 1 60S RIBOSOMAL PROTEIN L4-B × 1 (P49626) 60S RIBOSOMAL PROTEIN L17-A × 1 (P05740) 60S RIBOSOMAL PROTEIN L19 × 1 (P05735) 60S RIBOSOMAL PROTEIN L25 × 1 (P04456) 60S RIBOSOMAL PROTEIN L26-A × 1 (P05743) 60S RIBOSOMAL PROTEIN L35 × 1 (P39741) 60S RIBOSOMAL PROTEIN L39 × 1 (P04650) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RL31A_YEAST
Isoform —
PDB entities 13
Chains and sequence ranges Author chain M; PDBConstruct 1–113; UniProt 1–113

60S RIBOSOMAL PROTEIN L35

OrganismNot specified

UniProt P39741

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 11 RNA 4 SEC SIXTY-ONE PROTEIN HOMOLOG × 1 (P38353) PROTEIN TRANSPORT PROTEIN SSS1 × 1 (P35179) PROTEIN TRANSPORT PROTEIN SEB2 × 1 (P52871) 25S RRNA × 1 25S RRNA × 1 25S RRNA × 1 25S RRNA × 1 60S RIBOSOMAL PROTEIN L4-B × 1 (P49626) 60S RIBOSOMAL PROTEIN L17-A × 1 (P05740) 60S RIBOSOMAL PROTEIN L19 × 1 (P05735) 60S RIBOSOMAL PROTEIN L25 × 1 (P04456) 60S RIBOSOMAL PROTEIN L26-A × 1 (P05743) 60S RIBOSOMAL PROTEIN L31-A × 1 (P0C2H8) 60S RIBOSOMAL PROTEIN L39 × 1 (P04650) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RL35_YEAST
Isoform —
PDB entities 14
Chains and sequence ranges Author chain N; PDBConstruct 1–120; UniProt 1–120

60S RIBOSOMAL PROTEIN L39

OrganismNot specified

UniProt P04650

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 11 RNA 4 SEC SIXTY-ONE PROTEIN HOMOLOG × 1 (P38353) PROTEIN TRANSPORT PROTEIN SSS1 × 1 (P35179) PROTEIN TRANSPORT PROTEIN SEB2 × 1 (P52871) 25S RRNA × 1 25S RRNA × 1 25S RRNA × 1 25S RRNA × 1 60S RIBOSOMAL PROTEIN L4-B × 1 (P49626) 60S RIBOSOMAL PROTEIN L17-A × 1 (P05740) 60S RIBOSOMAL PROTEIN L19 × 1 (P05735) 60S RIBOSOMAL PROTEIN L25 × 1 (P04456) 60S RIBOSOMAL PROTEIN L26-A × 1 (P05743) 60S RIBOSOMAL PROTEIN L31-A × 1 (P0C2H8) 60S RIBOSOMAL PROTEIN L35 × 1 (P39741) Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RL39_YEAST
Isoform —
PDB entities 15
Chains and sequence ranges Author chain O; PDBConstruct 1–51; UniProt 1–51

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id2ww9
Deposition date deposition_date2009-10-22
Structure title titleCryo-EM structure of the active yeast Ssh1 complex bound to the yeast 80S ribosome
Keywords keywords;RIBOSOMAL PROTEIN, RIBONUCLEOPROTEIN, TRANSMEMBRANE, PHOSPHOPROTEIN, SIGNAL SEQUENCE, MEMBRANE, RIBOSOME, TRANSPORT, RNA-BINDING, RRNA-BINDING, TRANSLOCATION, PROTEIN CONDUCTING CHANNEL, PROTEIN EXIT TUNNEL, ENDOPLASMIC RETICULUM, COTRANSLATIONAL PROTEIN TRANSLOCATION, ISOPEPTIDE BOND, PROTEIN TRANSPORT ;; RIBOSOME
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

2ww9__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

2ww9__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

2ww9__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)45.40 Å
Rg (electron density)47.39 Å
Total Rg47.21 Å
Atom count14301
Residues1586
Excluded volume246890 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 2ww9__assembly_1__model_1 pentadecameric (15) Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (15)

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7. Citations (1)