Rattus norvegicus
| Assembly | 物理组成 | 蛋白状态 | 分子拷贝数 | 共同组分 | 数据核对 |
|---|---|---|---|---|---|
| 1 | 蛋白单体 | 单体 | 蛋白 1 | MAGNESIUM ION × 1 SULFATE ION × 2 5'-deoxy-5'-[4-({[(2,3-dihydroxy-5-nitrophenyl)carbonyl]amino}methyl)-1H-1,2,3-triazol-1-yl]adenosine × 1 water × 1 | 与蛋白数一致 |
| UniProt名称 | COMT_RAT |
| Isoform | — |
| PDB实体 | 1 |
| 链与序列区间 | 作者链 A； PDB构建体 3–223； UniProt 44–264 |
页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。
| 条目编号 entry_id | 3a7d |
| 沉积日期 deposition_date | 2009-09-26 |
| 结构标题 title | Crystal Structures of rat Catechol-O-Methyltransferase complexed with new bi-substrate type inhibitor |
| 关键词 keywords | ;Methyltransferase, NEUROTRANSMITTER DEGRADATION, ALTERNATIVE INITIATION, CATECHOLAMINE METABOLISM, S-ADENOSYL-L-METHIONINE, Cell membrane, Magnesium, Membrane, Metal-binding, Phosphoprotein, Signal-anchor, Transferase, Transmembrane ;; TRANSFERASE |
| 实验方法 method | X-RAY DIFFRACTION |
页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 17.33 Å |
| Rg（电子密度） | 16.27 Å |
| 总 Rg | 17.24 Å |
| 原子数 | 1725 |
| 残基数 | 214 |
| 排除体积 | 30714 ų |
| 最大 q | 0.500 Å⁻¹ |
| 结构域编号 domain_id | d3a7da_ |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.66 — S-adenosyl-L-methionine-dependent methyltransferases |
| 超家族 Superfamily superfamily | c.66.1 — S-adenosyl-L-methionine-dependent methyltransferases |
| 家族 Family family | c.66.1.1 — COMT-like |
| 结构域编号 domain_id | 3a7dA00 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 150 — Vaccinia Virus protein VP39 |